Introduction to the Centre of Forensic Sciences, Toxicology Section
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Transcript Introduction to the Centre of Forensic Sciences, Toxicology Section
Centre of Forensic Sciences
Centre of Forensic Science
Ministry of Public Safety and Security
Public Safety Branch
FMO, EMO, OCC
Centre of Forensic Science
CFS Mandate
Provide excellent scientific laboratory services in
support of the administration of the justice system and
public safety programs
provide scientific examinations and interpretations
present independent objective expert testimony
to provide educational services to our client groups
conduct R&D to improve the quality of our work
Who are our clients?
Pathologists and Coroners
Police
Attorneys
Crown attorneys
Defense attorneys
Other Investigative Agencies (OFM)
Centre of Forensic Sciences
Centre Receiving Office
Biology
Chemistry
Documents and Photoanalysis
Electronics and Gaming
Firearms and Toolmarks
Toxicology
Centre Receiving Office
Responsible for receiving, screening and
distributing all incoming samples to the
various sections throughout the CFS.
Establish chain of custody of evidence
Biology Section
Crimes against people
– sexual assault,assault, homicides, hit and run
Some cases of crimes against property
– burglary, vandalism
DNA profiling
– blood, semen, hair
– for genetic matches in crimes or for identification purposes
Blood stain pattern interpretation
Examination of hair and fibre evidence
Chemistry Section
Conducts chemical and physical analyses
– paint, glass, fire debris, explosives, soils, metals, plastics and
petroleum products
Thermal Desorption GC-MS
– identification of volatile ignitable liquids in fire debris
Manual Headspace GC-MS
– identification of alcohols, ketones, HC gases
Pyrolysis GC-MS
– identification of paints and polymers, lachrymators and
explosives
Metallurgical and mechanical testing
Documents and Photoanalysis
Examine handwriting and machine produced documents
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Authenticity
Handwriting
Alterations
Erasures
Impressions
Signature comparison
Restoration and decipherment of damaged documents
Image enhance photographs and video
Take staff pictures and analyze photographs video
Electronics and Gaming
Examine electrical and electronic equipment
– To establish malfunction, misuse, or criminal use
Check magnetic recordings for tampering
Check mechanical and video gaming machines
– Do they function as games of chance
– Conform to regulations governing gaming devices
Firearms and Toolmarks
Examine firearms and ammunition:
– classify, test and check the mechanical condition of firearms
– identify type of weapon a bullet came from
– cross check items with unsolved cases
– examine wounds and shooting distance determinations
Examine tools and the marks left by them
– prying tools - tire irons, screwdrivers and pry bars
– cutting tools - knives and axes
– pinching tools - pliers, cutters and crimpers
Toxicology Section
5th & 6th floor at CFS in Toronto
NRL in Sault Ste. Marie
Staff of 45
– Clerical
– Managers
– Scientists
– Technologists
4000-5000 cases per year
Toxicology Services
Laboratory analysis of human body tissues
and fluids; non-biological materials
Interpretation of findings
Written and viva voce opinion evidence
Breath testing program in Ontario
Scientific research
Training and Education
Types of Cases
Death Investigations
– No anatomical COD, COD but impairment issue
– SIDS (< 2 years old) with no anatomical COD
– Occupational/Workplace Accidents (Inquest)
– Death in Custody (Inquest)
– Aviation deaths
– Homicides
– Fatal MVA
– Fire Death Investigations
Sexual Assault & Administer noxious substance
Impaired driving
Attempted murder, assaults & poisoning
No analysis cases
Traumatic injuries due to suicide
– Hangings and self-inflicted Gun Shot Wounds
Passengers in fatal MVA
Deaths clearly ascribed to natural causes
– Old age
– Cancer
Deaths in hospitals >24-36 hours after admission
Criminal cases: No history of drugs/alcohol use
No validated method available
Where do samples come from?
Biological
– Autopsies, Sexual Assault and DWI
– Blood, urine, stomach contents, liver,
vitreous, muscle, spleen,
Non-biological
– Crime scene evidence
– Tablets, spoons, syringes, powders, cups,
etc…
Autopsy samples
Blood
heart
peripheral
Urine
Vitreous humour
Stomach contents
Liver
Bile
Sexual Assault/Date Rape
Blood
Urine
No analysis cases
– No history
– > 24 hours
Blood kits
Cannot provide a roadside breath sample
Blood demand is made
Taken by Doctor or Nurse
2 tubes of blood are taken
2nd tube available for defense
Non-Biological samples
Syringes
Pipes
Cans
Bottles
Food
Non-Biological samples
Powders
Liquids
Tablets
Pastes
Oils
Cigarettes
How are analyses ordered?
Amount and type of sample
Drugs to be analyzed
General guidelines
Case history
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Age and sex of victim, medical history, drug use history
Medications recently ingested
Symptoms reported by victim or observed by witnesses
Time of occurrence and time of specimen collection
Hobbies and interests of the victim or suspect
Occupation of the victim or suspect
EXPERIENCE !!!!
IA Analytical group
Immunoassay is a screening technique used
to detect the presence or absence of a drug or
class of drugs in blood, serum and urine.
LC Analytical group
HPLC with diode array detectors (DAD)
Analyze for over 100 drugs
– Acetaminophen, barbiturates, mefenamic acid,
midazolam, oxazepam, salicylate …….
GC Analytical group
Alcohol screen
Carbon Monoxide
General Drug Screen
Single Quants
MS Analytical group
Confirmations
Identifications
Targeted Analysis using deuterated interal
Report Generation
interpretation of toxicological findings
therapeutic, toxic or fatal
Toxicology
Report
impairment
drug interactions
postmortem changes in drug levels
review of toxicological/pharmacological
literature and experience
Training (Scientist)
Educational background (B.Sc., MSc.
Ph.D.)
– toxicology, pharmacology, chemistry,
biochemistry, physiology, biology,
environmental science
On-the-job training
(2-3 years)
Training (Technologist)
Educational background (Diploma, B.Sc.)
On-the-job training
months