Transcript Slide 1

NIAID-Biodefense Proteomics Research
Programs
Peter McGarvey, Raja Mazumder, Hongzhan Huang, Jian Zhang and Cathy Wu
Protein Information Resource, Georgetown University, Washington, DC 20007
Abstract
PNNL
The National Institute for Allergy and Infectious
Diseases (NIAID) has created a biodefense
Harvard
proteomics program with the goal to “identify and
validate therapeutic drug targets for the next
generation of vaccines, therapeutics, and
diagnostics” for agents of concern in bioterrorism.
Scripps
The program consists of seven Proteomics Research
Centers and an Administrative Resource Center. In
addition to administrative support, the Admin Center
is developing a bioinformatics infrastructure that
includes a web portal for public dissemination, a
central proteomic database hosting the data and
technology protocols generated by each Proteomics
Center, and a protein knowledge system for data
integration, data mining and data analysis.
1: Project Catalog Summary View.
Summarizes all information currently available.
www.proteomicsresource.org/Resources/Catalog.aspx
Albert Einstein
U of Michigan
Myriad
D
A
T
A
Caprion
SSS
PIR
Administrative
Center
VBI
2: Master Protein Directory.
Allows you to browse and search the directory of proteins and reagents identified
by the NIAID Biodefense Proteomics Research Centers. The directory integrates
information from the UniProt, iProClass and PIRSF databases to link protein
sequence and functional annotation to experimental data.
5: Download Data.
Experimental Data can be
downloaded in community
formats (mzData) for further
analysis.
4: Protein Bank.
Protein Bank contains experimental data and
protocols from Proteomics Research Centers
Acknowledgements: Supported by National
Institutes of Allergy and Infectious
Disease/NIH Contract: HHSN266200400061C
Social and Scientific Systems
Protein Information Resource
Virginia Institute of Bioinformatics
3: Master Directory Links to Annotation.
Links proteins to functional family annotation
in PIRSF and other databases
Contact
[email protected]
WWW.PROTEOMICSRESOURCE.ORG