Transcript Diapositive 1

PROMOTING THE CREATION,
RELOCATION AND DEVELOPMENT
OF BIOTECH COMPANIES
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Genopole®: From a Bio-Park to a Bio-Cluster ...
A continuum dedicated to Biotechnology
Research
Companies
Hospital
University
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Genopole® : a Biopark fully integrated in the
Medicen Paris Region Bio-cluster
Non-Profitable Organisation
 Incorporated in 1998
 Creation & Development of a Bio-Park : Companies & Research Labs
Micell.
18%
Region
39%
30 Km
State
17%
Council
26%
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Genopole®: Building the most favorable
environment to develop Biotech companies…
International
Scientific
International
environment
Network
Versatile
Pre seed Fund
Real Estate
Offers and Services
Biotech
Companies
Shared
Clinical
Technical platforms
Network
Incubation and
development
Programs
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Genopole®: A stimulating Collaborative Scientific
& Education Environment
20 research labs, incl. 3 national-scale centres
 More than 900 scientists
 From major National Research Agencies
o …
Evry University and 3 engineer schools
 more than 12,000 students (34 % in wet sciences and engineering)
and 400 professors
Ambitious Integrative Programs
 iStem : Institute for Stem Cells (2005)
 iSSB : Institute for Systems and Synthetic Biology (2009)
 Institute for Biomaterials (2010)
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Genopole®: a new hospital and a center for
clinical and translational research
A new hospital is build on Genopole® campus
 Latest & Largest General Hospital build in France
 1,000 beds
 Opening May 2011
Genopole coordinates the construction of a center
for clinical and translational research
 3,000 m²
 New Approaches
 Opening late 2011
Genopole®: more than 83 000 m² dedicated to the
development of life science companies
Our facilities include space from “plug ‘n play” offices for
entrepreneurs to customised tenant lab & office spaces
Business Center (20-50 m²):
 Offices fully furnished, Meeting rooms, ...
Incubator with shared laboratory equipment
 for 50 to 300 m² wet lab & office suites
 Fully equipped with benches, sinks, deionised water,
autoclave, freezers, rt-PCR, …
customized spaces / specific demand and lay out
 for 300 to 2 000 m² and more wet lab, L2 & office suites
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Genopole®: State of the art shared technical
platforms and equipment
Sharing expertise, skills and resources

15 Platforms/Equipments end 2009

Management : 13 public labs, 1
private and 1 Genopole

Genopole investments ~ 20 M€

Headcount : 68 persons

Cumulated surface ~ 4200 m2

5 obtained national quality label

2 ISO 9001 v 2000 certification & 2
planned in 2009-2010
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more than 300 scientific publications

8 patents/licences
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Genopole®: State of the art shared technical
platforms and equipment
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CERFE and CERFAP(Animal facilities)
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Cell and Small Animal Irradiator
Imaging and cytometry platform
Bioinformatic annotation
DNA chips production
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Mass spectrometry platform
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Evr@Platform (augmented reality and virtual environment)
Plant DNA Microarray platform
Biophotonics Platform
Structural Biology Platform (NMR, AFM)
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15 Platforms
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Transmission electron microscopy
DNA and cells Bank
HTS Platform
Cell sorting station
Incubator shared equipements
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Genopole®: GMP production centers for drugs of
the future
The Present & the Future
 A GMP compliant biomanufacturing center for
proteins from mammalian cells (biotherapy,
monoclonal antibodies)
 A GMP compliant viral vector bioproduction
center (Genethon)
 A production centre of enzymes and
biocatalysis for industrial use.
 A GMP biomanufacturing centre using
alternative techniques : bacteria, yeast,
plants…
 An GMP oligonucleotides production center in
partnership
 A Laboratory to develop and optimise the best
expression systems
 A centre for filling, packaging and delivering
products under GMP compliant
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Genopole®: a team dedicated to foster creation
and development of biotech companies
Incubation
Finance 6
4
2
0
Market
Compet.
Bus Dev IP
Science(s)
Clinic&Reg
Scale up
Team
A Team of 6 multidisciplinary
Project Managers
 Combining solid complementary
backgrounds in pre-incubation, IP,
finance, valuations, biz. dev., fund
raising, licensing, …
Finance 6
4
Market
2
Compet
Bus Dev
0
Science(s)
Clinic&Reg
Scale up
IP
Team
Genopole®: a team dedicated to foster creation
and development of biotech companies…
Incubation
- Tailor-made Incubation Programs -
Development Phase
Incorporation Phase
 Access to the Best R&D tax Credit in Europe
 Cover 50% of all R&D costs in the 1st year
 40% the 2nd year and 30% in subsequent years
up to €100 million and 5% above
 Legal support for corporate
development
 Raise Public Money
 Direct relations with OSEO,
CFI, ANR, Medicen, …
 Drug Development
 Network of preclinical & clinical experts
 Access to French and European
authorities: AFSSAPS or EMEA
 Raise Private Money
 Network of BAs and VCs
 Business Development
 Direct Access to all French Tech Transfer Offices
(CNRS, Inserm, CEA, AP-HP, …)
 Network of business opportunities
 Network of international experts
Genopole®: a list of services to foster the
development of Biotech companies
Incubation
Genopole provides a whole list of services dedicated to
young biotech companies
 Senior administrative officers, Accounting, quality assurance,
onsite IT network support, human resources management, …
Genopole coordinates an European Grant Service
dedicated to SMEs ...
 Brings support to preparation and application phases but also in
the management of funded project
Genopole organises access to :
 Electronic libraries including scientific and competitive databases
 Annual Calls for Equipments and Post-Docs
Genopole®: with G1J IdF access to a pre-seed
Fund
Incubation
G1J - Genopole pre-seed Life Sciences Capital Fund
Initial Capital: 2.1 M€ - 16 private investors
Investment/project: 50 000 – 100 000 €
« From 1st day to 1st round of financing »
Allows access to the Oseo grant system and to National, Regional & EU grants
G1J - Genopole Regional Life Sciences Capital Fund
 Equity raise: 6 M€
 brings G1J to the Proof of Concept Fund level
 Investment/project: 300 000 – 500 000 €
Genopole®: More than 80 currently incorporated
companies and active projects …
GENOPOLE® ENTREPRISES
in 2008
LTK Pharma
69 biotech
Texcell companies
GlobalBio Energy
1023 FTE
207.81 M€ fund raised
144.11 M€ sales / 30 companies
NanoBH
670 granted/penting patents
28 products from IND to Phase III &
market
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Genopole®: an international network oriented to
biotech companies
International
Genopole manages an international network
 with international Cies, pharma laboratories,
foreign bioincubators and international venture
capital institutions,
Genopole is member of several European
consortium with European bioparks
 BioLink (FP5) Oxford, Munich, Cagliari, Jerusalem, Cardiff
 Natibs (FP6) Berlin, Barcelona, Karolinska, Tallinn, Tel Aviv, Inno
 CEBR (FP6) Cambridge, Oxford, Berlin, Munich, Heidelberg, Barcelona, Uppsala, Tallinn, Lyon
 Bio-CT (FP7) Torino, Cambridge (CEBR), Barcelona, Berlin, Debrecen & Inno
Genopole® Campus 1 Today & tomorrow
Centre de
Bioproduction
Restaurant
inter-entreprises
et Résidence
hôtelière
2011
Projet Gamma : production
GM P de lots cliniques de
vecteurs viraux de
Généthon
2011
Genavenir : Pôle
d’entreprises et
de laboratoires
Centre
de
Recherche
Clinique et
Translationnelle
Pépinière
Centre Hospitalier
Sud-Francilien
2011
CCIE
Genopole
Entreprises
Projet Crèche
2011
Genavenir :
Hôtels
d’entreprises
Our achievements ...
 20 research labs - 900 jobs 
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70 biotech companies – 1 000 jobsA comprehensive 83 000 m² real estate offer
A team dedicated to development
Services and a Europe Grant service
 17 platforms and equipments
 Corbeil Evry Hospital & Clinical
and Translational Research Center
 GMP Biomanufacturing Center opening
soon and 4 others biomanufacturing
project running
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For more Informations …
http://www.genopole.fr
Emmanuel DIAZ
Economic Development Director
Place de l’Agora BP 62
91002 EVRY Cedex
Tel + 33 (0)1 69 91 59 38
[email protected]
www.agglo-evry.fr
Caroline Mercier
Head of networks and investments
Essonne Development Agency
6 cours Monseigneur Roméro
91025 Evry Cedex
Fixe : + 33 (0)1 69 91 42 56
mail : [email protected]
Delphine Beau
Life Sciences Director
Paris Region Economic Development Agency
www.paris-region.com
Tel :(+33 (0)1 58 18 69 62
Mob.:+33 (0)6 03 85 66 32
Eric Lameignère
Genopole Entreprises Director
5, rue Henri Desbruères
F-91057 Evry Cedex
Tel.: +33 (0)160 878 306
Tel :(+33 (0)1 58 18 69 62
Mob.:+33 (0)6 03 85 66 32
[email protected]
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