Transcript Biosensors
Anthony Catalano Any device that analyzes a biological compound into a measurable signal Composed of a bioreceptor, transducer, and an electronic peripheral Bioreceptor: Part of device Enzymes, Antibodies, or nucleic acids. Piezoelectric, Thermal, Electrochemical, and Optical LED Display that interacts with a biological material to identify and interact with a target molecule Transducer: Electronic Peripheral: Part of the device that turns the target molecule into a measured signal Turns the measured signal into a graphical user interface (GUI) utilizing microprocessors Piezoelectric: crystal detector uses the change of frequency to calculate change in mass Thermal: measures change in heat (exothermic, endothermic) Electrochemical: (Amperometric, or potentiometric) uses electrodes to measure current Optical: uses Surface Plasmon Resonance (SPR), or reflectance to identify various biological molecules Measures Mass Measures heat, requires large sample size, complicated devices Amperometric are among the most common transducers for biosensors Great for identifying antigens, or cancerous cells in a solution Current Applications Lab-on-a-chip Pollutant Control Patient Diagnosis Detection of harmful pathogens, bacteria, toxic compounds Future Disposable Low Cost Increased Sensitivity Improved Microprocessors Multipurpose Environmental friendly 1. Pohanka, Miroslave. "Electrochemical Biosensors – Principles and Applications." Journal of Applied Biomedicine (2008): 58-62. Web. 20 Nov. 2012. 2. Mutharasan, Raj. "Biosensors." Engineering Biotechnology. N.p., n.d. Web. 20 Nov. 2012. <http://www.gatewaycoalition.org/files/Hidde n/sensr/ch1/1_1f.htm>. 3. Kumar, Ashok. "Biosensors Based on Piezoelectric Crystal Detectors: Theory and Application." Department of Mechanical Engineering and Center for Microelectronics Research (2010): 1-6. Web. http://www.tms.org/pubs/journals/JOM/0010/ Kumar/Kumar-0010.html 4. Dey, D., and T. Goswami. "Optical Biosensors: A Revolution Towards Quantum Nanoscale Electronics Device Fabrication." Journal of Biomedicine and Biotechnology 2011.348218 (2011): 0-7. Web. 20 Nov. 2012. <http://http://www.hindawi.com/journals/jbb /2011/348218/>.