Intro. to Medical Microbiology

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Transcript Intro. to Medical Microbiology

Introduction
BIO 411
Medical Microbiology
The Prophet’s View of Education
• “You are all in school. Do not waste your
time. This is a time of great opportunity
that you will never have again as long as
you live. Make the most of it right now….
• “…you can’t afford to waste your time.
There is so much to learn. Give it the very
best that you have.” – Gordon B. Hinckley
Syllabus
• So what are we going to learn about this
semester?
• Syllabus
• What does it take to succeed in Bro. Wray’s
class?
• First Assignment – Elder Eyring Article
Medical Microbiology
Chapter 1
Intro. to Medical Microbiology
Intro. to Medical Microbiology
• History of Microbiology
– Anton van Leeuwenhoek (1674)
– Friedrich Henle (1840) – Germ Theory of
Disease
– Robert Koch and Louis Pasteur (late 1800’s)
– Alexander Fleming (1928) - Penicillin
Intro. to Medical Microbiology
• Groups of Microorganisms
– Viruses
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DNA or RNA genome
Protein coat (capsid)
Some have a membrane envelope
Obligate intracellular parasites
Pathogenesis
Diseases?
Intro. to Medical Microbiology
– Bacteria
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Prokaryotic organisms
Peptidoglycan cell wall
Gram + and Gram –
Cell shapes and arrangements
Pathogenesis - toxins
Diseases?
Intro. to Medical Microbiology
– Fungi
• Eukaryotic
• Yeasts, molds, dimorphic fungi
• Diseases?
– Parasites
Intro. to Medical Microbiology
• Microbial Disease
– Most organisms don’t cause a single disease
• Staphylococcus aureus, meningitis, etc.
– Few microbes are always pathogenic
– Exogenous infections vs. endogenous infections
• Normal Flora