Transcript Slide 1

Tracking Cancer
Development and
Movement
Interim Presentation
February 19, 2005
Team 004
Albuquerque Academy
Team Members: Punit Shah
Karalyn Baca
Teacher:
Jim Mims
Mentor:
Dr. Gene Wong
Contents
Project Objectives
Research
Math Model
Code & Program
To Do
Questions
February 19, 2005
Tracking Cancer Development and
Movement
2
Project Objectives
To model the development and
propagation of melanoma skin cancer
To see the patterns in the movement of the
melanoma cancer through the body
February 19, 2005
Tracking Cancer Development and
Movement
3
Research
Basic anatomy of skin

Layers
Epidermis, outermost layer of skin
Germinal layer, where new skin is
produced
Dermis, where blood vessels, hair
follicles, and such are

Melanocytes
Between germinal layer and
dermis
Make the pigment that in turn
makes the skin whatever color it is
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Tracking Cancer Development and
Movement
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Research
What causes skin cancer

On a cellular level
Cells are genetically changed by UV rays
As they are unnatural, they thrive and continue to grow
They make greater and greater pigment in the
melanocytes
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There are predetermined factors and
environments that increase the change of getting
cancer
Ways to protect from UV rays
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Movement
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Research
How malignant melanocytes develop
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Their effect on the germinal layer and epidermis
The movement of malignant cells at a local region
The movement of malignant melanocytes through the
body
Their effect on organs
The symptoms of melanoma

The effects of malignant melanocytes on other cells
and tissues
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Movement
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Math Model
Initially, tumor growth
is exponential
As competition
increases, cells start
to die
Cancer growth follows
a sigmoidal curve
A sigmoidal curve
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Tracking Cancer Development and
Movement
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Math Model
Cancer starts as a sphere
When cancer spreads, tends to spread
horizontally rather than vertically
When it continues, smaller tumors are created
that continue the cycle
To compute, we must look at many tumors’
development at once
Uses great computing power, must be simplified
Resource burdening will not be incorporated
initially
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Movement
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Math Model
Will start with taking few factors into
account
Will look at a simple, spherical growth and
may have possible lateral spread in initial
version
When diameter exceeds 5mm, new
tumors created around old tumor
Old tumor will then die
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Movement
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Code & Program
Program’s splash screen
February 19, 2005
Microsoft Visual Basic 6.0
will be used
Basic code has been
developed and windows
have been setup
Plan to have two output
windows
 Skin Model with
cancer
 Time to Cancerous
Cell count graph
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Movement
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Code & Program
Plan to have procedures of classes be the
different properties of a cell in the model
Properties include
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Cancerous on non-cancerous
Location in respect to different cancer tumors
An array will hold the different cells of the
model
The GUI of the model will be updated
periodically to show progress
February 19, 2005
Tracking Cancer Development and
Movement
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Cancerous Cell Count
Code & Program
Time
The cancerous cell
count graph
The cancer
tumor
February 19, 2005
The cancer model
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Movement
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To Do
Complete program
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Develop code to properly graph number of cancerous
cells
Add variables of growth such as partial treatment and
random growth
Show the cancer’s effect on other body parts
Add the growth of satellite nodules
Track general movement and growth throughout the
body
Thoroughly benchmark and test the program
February 19, 2005
Tracking Cancer Development and
Movement
13
Tracking Cancer
Development and
Movement
Interim Presentation
February 19, 2005
Team 004
Albuquerque Academy
Team Members: Punit Shah
Karalyn Baca
Teacher:
Jim Mims
Mentor:
Dr. Gene Wong