Transcript Cancer

Cell Cycle
Control
and
Cancer
Mitosis Gone Wild!
Tan = Sexy, and
Risking Death
Tan = Sexy?
Tan = Sexy?
Naomi
Tumor
Means “swelling”
Come to refer to abnormal
growth of tissue.
Two types of tumors:
Benign
Malignant
Benign
Means “not life
threatening”
Do not invade other
tissues.
Do not break apart and
spread to other parts of
the body (metastasize)
Can grow really big and
become a serious health
problem, possibly life
threatening.
Premalignant
Benign tumors are at
greater risk for
turning into “cancer”
than other tissue.
If they start to
“degenerate” then
they are called
premalignant.
Malignant
 Cells dedifferentiate
– lose
specializations like
cilia and axons.
 Metastasize
 Break away from
tumor move through
blood stream to
other parts of the
body
 Divide and grow into
another cancerous
tumor.
Cancer
Testicle Cells in you Lungs!
Breast Tissue in your Brain!
Contact Inhibition
Cell to cell
contact
usually stops
cell division,
not with
cancerous
cells.
Oncogenes
 Genes control cell
division – produce
checkpoint proteins.
 Proto-oncogenes
 Mutations can cause
cells to go through
mitosis too often =
tumor.
 0 or + signals for
division.
Tumor suppressor gene
Send either 0
or – signals.
Carcinogens
Physical
UV
Heat
Chemical
Bind with DNA
Biological
Viruses
Apoptosis
Cell dies when
damaged
excessively.
Relies on a gene.
When the gene is
mutated apoptosis
does not happen so
the cell can become
a tumor.
Cancer Music Video
http://www.yout
ube.com/watch
?v=mHOX434PvE&feature=re
lated