Transcript Cancer - PharmaEuphoria

Review on Cancer and role of
medicinal plants
PRESENTED BY
Mr. Abhishek Chouhan
M. Pharma* (Industrial Pharmacy)
Introduction
 Cancer is characterized by the uncontrolled growth
and spread of abnormal cells that is caused by
external factors, like tobacco, infectious organisms,
unhealthy diet & internal factors like inherited
genetic mutations, hormones and immune
conditions.
Types of Cancer
 CARCINOMAS- Cells that cover internal and external
parts of the body such as lung, breast and colon
cancer
 SARCOMA- Bone, cartilage, fat, connective tissue and
muscle
 LYMPHOMAS- Lymph nodes and immune system
tissues
 LEUKEMIAS- Bone marrow and often accumulate in
the bloodstream
 ADENOMAS- Thyroid, pituitary gland, adrenal gland
and other glandular tissues
Comparison of cancer rates in India & USA
Rates as per 100,000 Population
Ten Leading Cancer Types for the Estimated New Cancer Cases and Deaths, by Sex, United
States, 2008.
Cancer Statistics for Males, 2008
Ten Leading Cancer Types for the Estimated New Cancer Cases and Deaths, by Sex, United
States, 2008.
Cancer Statistics for Females, 2008
Ten Leading Cancer Types for the Estimated New Cancer Cases and Deaths, by Sex, United
States, 2008.
Risk Factor for Cancer
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Physical activity
Obesity
Smoking
Alcohol consumption
Diet
Dietary fats and fiber
Spices and additives
Micronutrients
Risk Factor for Cancer
Increased risk factor
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Betel quid chewing
High body mass index
Saturated fat intake
Human papillioma virus
Tobacco use
High temperature foods
Chilies & spicy foods
Dry fish
High consumption of rice
H. pylori
Decreased risk factor
 Diet high in vegetables, fruits,
fish, eggs
 Vit. C & E
 Diet high in carotenoids
 Diet high in fish
 High physical activity
 Green tea, Turmeric, Tomato,
Basil
Turmeric
 Curcumin has been studied in multiple human
carcinomas including melanoma, head and neck,
breast, colon, pancreatic, prostate and ovarian
cancers.
 Epidemiological studies attribute the low incidence of
colon cancer in India to the chemopreventive and
antioxidant properties of diets rich in curcumin
Neem
 It has Gallic acid, epicatechin and catechin.
 Recent studies indicated that an ethanolic extract of
neem has been shown to cause cell death of prostate
cancer.
 Different studies indicate its use against buccal
carcinogenesis, skin carcinogenesis, gastric
carcinogenesis & melanoma.
Wheatgrass
 Wheatgrass extract contains
chlorophyll, an antioxidant, may affect
cancer prevention.
 Additionally, selenium and lactrile
present in wheatgrass have anti-cancer
properties. Selenium builds a strong
immune system, and can decrease the
risk of cancer.
References
 Cancer Facts & Figures 2015, American Cancer Society
(ACS) , 2015, 1
 Sinha R. “Cancer Risk and Diet in India” J Postgrad
Med 2003, 49, 222-228
 Ahmedin Jemal et al, “Cancer Statistics, 2008” A
Cancer Journal for Clinicians, 2008, 58 (2) 71-96
 Radha Sharma et al “CANCER TREATMENT: AN
OVERVIEW OF HERBAL MEDICINES” WJPPS, 2014,
Vol. 03 (8) , 222-230
References
 Preeti Singh Sisodiya “PLANT DERIVED ANTICANCER
AGENTS: A REVIEW” IJRDPL, 2013, Vol. 02 (2), 293-308
 Satyavati Rana et al “Living life the natural way –
Wheatgrass and Health” Open Access Functional
Foods in Health and Disease, 2011, 1 (11) 444-456
 Ratnakaram Satya Teja K et al “Anticancer property
of plant products” IJRAP 2011, 2 (1) 111-113
 Reason Wilken et al “Curcumin: A review of anticancer properties and therapeutic activity in head
and neck squamous cell carcinoma” Molecular
Cancer Open Access 2011, 10-12
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