Drug information resources

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Transcript Drug information resources

Drug information resources
Done by:Fatimah Al-Shehri
Pharm.D
Tertiary Literature:
It summarizes and interprets the primary literature.
Types of tertiary literature:
Textbooks, compendia, handbooks, articles reviews, manuals, and online
drug databases (UpToDate, Micromedex,Medscape,lexicomp etc…) It
can be either
printed or electronic.
Tertiary Literature:
Advantages:
Convenient, accessible
Inexpensive
Often available online
Presence of reference citation that can be retrieved for more specific
information
Disadvantages:
Lag time (delay in publication)
Lack of details about specific topics
Author’s interpretation
Secondary Literature:
Used to locate primary literature and includes indexing and abstracting
services.
Indexing services :provide bibliographic citations, with or without an
abstract.
Abstracting services :provide summaries of primary literature articles in
addition to the citation of that article.
Examples of secondary literature:
>-MEDLINE / PubMd
.-EMBASE (Elsevier).
-Iowa Drug Information System (IDIS).
Secondary Literature:
Advantages:
Simple search strategies
Very current citation information
Access point for tremendous amount of primary sources
Disadvantages:
Incomplete information
Not specific to researcher needs
Some databases are expensive to access such as EMBASE
MEDLINE/PubMed:
MEDLINE/PubMed:
MEDLINE/PubMed:
Primary literature:
Primary literature is one that provides original work, such as
experimental or observational studies, research abstracts, case reports,
analyses, or observations.
Journals, meetings symposia, and conference proceedings are considered
primary information resource.
Primary literature:
Advantages:
Most current published source.
Useful when specific information is needed.
Disadvantages:
Overwhelming volume.
Necessity for article critical appraisal.
Takes long time to obtain the actual article.
Few articles are available in a free full text format.
Which literature to use?
Micromedex
Micromedex
UpToDate:
UpToDate:
Electronic Medicines Compendium
www.medicines.org.uk/emc
Electronic Medicines Compendium
Electronic Medicines Compendium
Martindale
MHRA Drug Analysis Prints (DAP)
MHRA Drug Analysis Prints (DAP)
Pediatrics
Specific Information:
When calculating a dose on a mg/kg basis never exceed the maximum
recommended
dose (usually the adult dose). If the child is obese consider calculating
using ideal
body weight
Consider if the patient is a young infant (less than 3 months old), were
they premature? If so, what is their gestational age ?
Consider if the route is oral, is the child able to swallow tablets
References:
The Harriet Lane Handbook
Neofax (available as a handbook at the Inpatient Pharmacy)
Micromedex (see pediatric dosing)
UpToDate (see dosing: pediatric)
Electronic Medicines Compendium. www.medicines.org.uk/emc
The Harriet Lane Handbook
Toxicology
Specific Information:
How much of the medication has been taken, and how long ago ?
Consider the circumstances of the exposure, Was this an accidental,
deliberate
overdose, or an administration error
Consider if the patient having any symptoms from poisoning
References:
POISONDEX
UpToDate
Electronic Medicines Compendium. www.medicines.org.uk/emc
(see overdose)
POISONDEX
Click My JAMAevidence
How to use PubMed
http://www.youtube.com/watch?v=MMaPxeM
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