Patients Can Be Such “Pills”

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Transcript Patients Can Be Such “Pills”

Dan Lindenmeyer, RPh
Pharmacy Mgr. - Dillons
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6 main categories
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Hypertension
Antidepressants
Pain meds
Cholesterol Reducers
Antibiotics
Antacids-Acid Reducers
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Company has exclusive rights to market drug
for 17 years after a patent has been approved
◦ Most of the time patents are obtained while trials
are being run
◦ By the time drug hits the market only 8 to 10 years
are left on patent
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AB rated generics must be therapeutically
equal
◦ The med must dissolve in the body at the same rate
and produce equivalent levels
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Cardiology
Hypertension
Cholesterol reducers
Antibiotics
Diabetes
Weight Loss
Depression and Alzheimer’s
Acid Reducers-antacids
Herbal Supplements
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Strong Narcotics
◦ Percocet, Oxycontin, Percodan, Demerol
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Mid-Level Narcotics
◦ Lortab, Lorcet
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Non-Narcotic Controlled
◦ Darvocet
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NSAIDS
◦ Ibuprofen, naproxen, diclofenac, etodolac,
indomethacin, tramadol
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COX-II Inhibitors
◦ Celebrex
◦ Mobic
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Anti-arrhythmics
Calcium Channel Blockers
Ace Inhibitors
Angiotensin receptor blockers
Beta blockers
Diuretics
Lanoxin---Antiarrhythmic
Pacerone—Antiarrhythmic
Mexilitine—Antiarrhythmic
Nitroglycerin—angina agent
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Pressure on arterial walls
◦ Blood pressure meds work by blocking
receptors in arterial wall and relaxing
the artery
◦ Diuretics remove fluids to decrease fluid volume of
the body to lower blood pressure.
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Beta blockers
◦ Atenolol, metoprolol, propranolol
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ACE Inhibitors
◦ Lisinopril, enalapril, benazapril
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Calcium channel blockers
◦ Amlodipine, diltiazem
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Angiotensin receptor blockers
◦ Cozaar, Hyzaar, Micardis
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Diuretics
◦ Furosemide, triamterene/HCTZ,
hydrochlorothiazide
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Previously d/c blood thinners 10 days before
dental extraction or scaling and root planing
Rebound effect after antiplatelet interruption
can result in stroke or MI
Minor surgical procedures can be carried out
safely without altering antiplatelet therapy
◦ Simple extractions <3 teeth
 Additional visits for more than 3 teeth
◦ Gingival surgery
◦ Crowns and bridges
◦ Scaling and surgical removal of teeth
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Beta lactam antibiotics
◦ Penicillins
◦ Cephalosporins
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Macrolide
◦ Erythromycins
◦ Zithromax
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Quinolones
◦ Levaquin
◦ Ciprofloxacin
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Sulfonamides
Tetracyclines
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Statins
◦ No Generics
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Lipitor
Zetia
Tricor
Vytorin(combo of Zetia and Simvastatin)
◦ Generics
 Mevacor-Lovastatin
 Zocor-Simvastatin
 Pravachol-Pravastatin
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Niacin
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Injectable Insulins
◦ Humalog--Novolog
◦ Lantus
◦ Humulin—N,R,U,70/30
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Increase Insulins effect
◦ Alcohol, anabolic steroids, beta blockers, MAO
inhibitors, tetracyclines, salicylates
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Decrease Insulins effect
◦ Oral contrceptives, corticosteroids, niacin, smoking,
thiazide diuretics, thyroid hormones
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Metformin
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Glyburide and glipizide
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Glimepiride
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Avandia
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Actos
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Phentermine
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Xenical---Alli
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Natural Supplements
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How it works: Chemical in brain called
serotonin is at higher cellular
levels
Most antidepressants block re-uptake of
serotonin to produce their effects
Very common condition
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Tricyclic
◦ Amitriptyline, nortryptyline, imipramine
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Tetracyclic
◦ Remeron
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SSRI
◦ Prozac, Zoloft, Lexapro, Celexa
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SSRI & Norepinephrine
◦ Effexor and Cymbalta
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MAO-Inhibitors
◦ Parnate, Nardil
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H2 antagonists
◦ Zantac
◦ Tagamet
◦ Axid
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Available OTC and Rx
PPI’s
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Prevacid
Protonix
Aciphex
Nexium
Prilosec –only one available as an OTC
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Namenda
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Aricept
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Non-Sedating
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Zyrtec
Allegra
Clarinex
Claritin—OTC
OTC
◦ Benadryl
◦ Chlorpheniramine
◦ Clemastine
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Not regulated by FDA
◦ No proof of effectiveness
◦ Take at own risk
◦ Products have been proven safe at
recommended doses
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Very popular alternative to getting
prescriptions
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Resources:
◦ Drug information handbook for dentistry-7th
Edition
◦ Clinical pharmacology