Transcript Slide 1

Explain why digestion of large food
molecules is essential.
What sort/size of food do we normally
eat?
Normally the biggest thing we can fit is a
mouth-full!
http://www.noticiascadadia.com/uploads/pics/burger_king.jpg
Where does our food that we eat get used up?
In order to get into here it has to pass
through a membrane.
http://www.answersingenesis.org/assets/images/articles/nab/human-cell.jpg
Making the food go from this big……
…To molecules able to pass
through a plasma
membrane is called
Digestion.
http://www.noticiascadadia.com/uploads/pics/burger_king.jpg
Lipid
molecule
Amino acid molecule
http://www.reactivereports.com/8/images/nand.jpg
http://www.ncl.ac.uk/bmsu/assets/photos/glucose-molecule.jpg
http://www.solvias.com/documents/Grafiken/images_services/molecule_weiss.jpg
Explain the need for enzymes in
digestion.
Digestion can be split into 2 types:
Mechanical Digestion – The physical breaking of the food.
Chemical digestion – the chemical break down of the food into its constituent parts.
Can you think of where mechanical digestion takes place?
Biting the food
Chewing the food
Churning in the stomach
But even that doesn’t get the food small enough to
pass through a phospholipid bilayer and into a cell!
If we were to wait till the food naturally fell apart into
small enough pieces it would take more than 2
months!
Look at this animation of fruit decaying…….
http://www.youtube.com/watch?v=FgKZp18jJnA&featu
re=related
Or we could always cook it……..
Because our body works best
at 36oC we can’t cook it and
we cant hold it inside us for 2
months so instead….
We use something that speeds up
reactions and reduces the
temperatures that are needed for
reactions……. Enzymes
State the source, substrate, products
and optimum pH conditions for one
amylase, one protease and one lipase.
Type of
enzyme
Name of
enzyme
(pH)
What it
works
on
What it
produces
Where
Amylase
Salivary
Amylase
pH 7
Pepsin
pH 1.5-3
Starch
Maltose
Mouth
Protease
Lipase
Proteins Dipeptides Stomach
(PolyPeptide)
Pancreatic Lipids Fatty acid Duodenum
Lipase
(fats and
and
oils)
Glycerol
pH 7
Some of these reactions need very specific conditions.
What keeps the mouth from becoming acid?
What does the stomach produce to get a pH of 1.5 – 3? Won’t this damage the
stomach? How does the stomach normally defend against this damage?
When this defense goes wrong…….
http://www.helico.com/images/du_gu_1.jpg
What does bile do?
This is called emulsification. Why is it
important to the speed at which
Lipase works?
How are the different regions of the gut kept separate?
There are 2 other sphincters in
the gut where are they?
http://www.sjhsyr.org/sjhhc/hidc07/graphics/images/en/19223.jpg
Diagram of the digestive system.
Learn these labels:
Mouth
Oesophagus
Stomach
Duodenum
Large Intestine
Small intestine
Rectum
Anus
http://www.gutenberg.org/files/18559/18559-h/images/figure10.png
Now test yourself
Mouth
Oesophagus
Stomach
Duodenum
Large Intestine
Small intestine
Rectum
Anus
http://www.gutenberg.org/files/18559/18559-h/images/figure10.png
Outline the function of the stomach,
small intestine and large intestine.
There are several processes you need to know
about; what they are and where they happen.
Ingestion: Taking food into the digestive system.
Normally happens in the mouth.
Digestion: Breaking the food down to soluble bits
Happens between the mouth
and the start of the small
intestine.
http://urbanext.illinois.edu/diabetes/images/food_digestion.gif
Distinguish between absorption and
assimilation.
Absorbtion: This is when the soluble food
particles which have been digested get
passed from the intestines into the
blood stream.
Assimilation: is when the soluble substances are
taken from the blood stream and used
in the body cells.
Egestion: Is the removal of the bits of food that
have not been digested. It normally
occurs at the anus!
So what happens where? Fill in the following
table:
Organ
What process
happens
there?
What makes the organ
good at its job?
Mouth
Ingestion and
Digestion
Stomach
Digestion
Duodenum
Digestion
Pancreatic duct, bile duct.
Absorption of digested
products.
Villus, microvillus, length, blood supply,
Small
Intestine
Large
intestine
Anus
Absorption of water
and minerals
Egestion
Teeth, saliva, biting and chewing
Acid, protease, gastric pits, churning
Explain how the structure of the villus
is related to its role in absorption and
transport of the products of digestion.
http://www.jpp.krakow.pl/journal/archive/0605_s3/gfx/rys0506_9.jpg
http://www.biog1105-1106.org/demos/105/unit6/media/villus.structure.jpg
What makes a villus so good at its job?
Think about Surface Area. What is the effect of surface area on rate of
diffusion? How is the surface area of the gut increased with villi? How is the
surface area of the villus increased with microvilli?
Think about the distance over which products must diffuse. How does a
villus ensure the distance is small?
Think about how the absorbed products of digestion are taken away
from the gut. What is it in a villus that allows this?
The villus is very active. What cellular processes are occurring across
the cell membranes that would require lots of energy. What supplies
this energy?
Find out about a lacteal.