Transcript Hemophilia PPT

Hemophilia
By: Rebecca Peterson, Owen Comer, Quaevon Anderson, and Grace Hodges
Basic Information
• Hemophilia A
• Classic hemophilia
• Factor VIII deficiency
• Hemophilia B
• Christmas disease
• Factor IX deficiency
Grace
The name hemophilia
was chosen because
“hemo” means blood
and “philia” means like.
Discovery of hemophilia
Grace
Hemophilia was discovered in Plymouth, New Hampshire, in 1720. It was not
named until 1828, though. The men who discovered and named hemophilia are
Friedrich Hopff and Dr. John Conrad Otto. The reason this disease was
discovered is because it was traced back through three generations of women in
Plymouth. It was also mentioned in 2nd century AD in a collection of Jewish
Rabbinical writings.
How is Hemophilia cured?
Quaevon
• Hemophilia can’t be cured, but it can be treated and controlled.
• Self treatment: Tranexamic acid by mouth (Lysteda or by injection).
and also common-IV fluids
Hemophilia is treated by injecting the missing factor replace therapy.
Living with hemophilia
Quaevon
If you or your child has hemophilia you can take steps to prevent
bleeding problems. improvements in treatment a child who has
hemophilia today is likely to live a normal lifestyle.
Symptoms and Effects
Owen
Symptoms:
• Large and deep bruises
• Joint pain and swollen joints
• Unexpected bleeding
• Internal bleeding
Effects:
• When injured, you can bleed for a prolonged amount of time.
• Joints don’t function as well as they should.
• Loss of joint space
Diagnosis of Individual
Owen
• Doctors use clotting factor tests. These are required to diagnose a
bleeding disorder, and show the type of the hemophilia and the
severity.
• They also use screening tests, which are blood tests that show if the
blood is clotting properly.
• ⅓ of babies who get hemophilia have no family history of the
disease
• Usually, people have the disease at the start of their life, but in
some rare cases, someone can develop it later in life.
Prognosis of Individual
Quaevon
people who get care are provided with treatment.
A person without proper treatment for their hemophilia may not
live to see adulthood. If the patient is treated, they usually live
about 10 years less than the average male without hemophilia.
People with hemophilia bleed more than people without
hemophilia. If the bleeding is severe enough, the patient may
require medical attention.
Current research
Rebecca
Currently Wake Forest school of medicine is trying to find out how to
use gene therapy to cure people with hemophilia. They think that
they might be able to place a stem cell from an adult into the
patient's body with the ability to make more of the clotting factor
VIII.
Treatments and medications
Rebecca
There is currently no cure to hemophilia but there are some
medications that you can take to help such as lysteda. You can
also have an injections of plasma to help with your clotting. You
can also possibly have gene therapy done to help with the
preventing of hemophilia, but it hasn’t been tested much so the
results are dangerous.
A Famous person with hemophilia
Grace
•Abraham Lincoln, America’s 16th president had hemophilia. The
genetic disease did not stop him from ending slavery and improving
the country. He was still a good president, and did not die because of
his hemophilia (he was assassinated). Lincoln also had a family, and
led our country for a little over one term (killed in office in term two).
Abraham Lincoln also had other illnesses, such as Multiple Endocrine
Neoplasia 2B. In conclusion, this case of hemophilia did not greatly
affect Lincoln.
Bibliography
• Www.google.com/search?q=Hemophilia.
Grace
Www.google.com/search?q=Hemophilia (n.d.): n. pag. Hemophilia.
Google. Web.
• Donald, David H., Deborah Hayden, Samuel A. Schreinen, John G. Sotos,
and Ronald C. White, “Medical and Mental Health of Abraham Lincoln”Wikipedia, the free encyclopedia. n.p. n.d. Web. 14 Mar. 2016
• Chien-Kang Ding, Guest Lecture”-Duke University: Genetics outreachorganization, Durant Road Middle School, 23 Feb. 2016
• "Diagnosis." Centers for Disease Control and Prevention. Centers for
Disease Control and Prevention, 13 Sept. 2011. Web. 04 Apr. 2016.
• "Hemophilia." Centers for Disease Control and Prevention. Centers for
Disease Control and Prevention, 16 Mar. 2016. Web. 04 Apr. 2016.
• Koyfman, Andrew, and Rob Hunter. "Stop the Bleeding: Can Gene
Therapy Finally Cure Hemophilia? | Xconomy." Xconomy RSS. N.p., 22
Mar. 2015. Web. 05 Apr. 2016.