Transcript Treatment
Shariati Hospital
Endocrinology and Metabolism Research Center (EMRC)
Tehran University of Medical Sciences (TUMS)
02/04/2016
19th Annual Iranian Congress of PM&R
Diabetes Mellitus; the third most populous country
(more than 350 million people)
A chronic metabolic disease of high morbidity and
mortality which has become a public health problem.
Alarm: increasing of Type 2 DM at
younger ages because of lifestyle
behaviors such as limited physical
activity, excessive food intake,
and greater prevalence of obesity.
Upper
extremity
Lower
extremity
Spine
Totally
Adhesive capsulitis, calcific periarthritis
in shoulder,
Dupuytren contracture, limited joint mobility, carpal tunnel
syndrome, flexor tenosyinovitis, complex regional pain
syndrome
Hip avascular necrosis (AVN), restless leg syndrome (RLS),
posterior tibial tendon rupture, Charcot’s arthropathy,
osteoarthritis, diabetic muscle infarction, diabetic foot,
adhesive capsulitis of hip, femoral and peroneal
mononeuropathies,, hammer toe, mallet and claw toe, limb
amputations
Diffuse idiopathic skeletal hyperostosis (DISH), radiculopathies,
Lumbosacral spondylosis (OA)
Osteopenia, sarcopenia
Painful restricted shoulder with normal radiographs
2 to 4 times more common in women than men
Most frequently between 40 and 60 years of age
Usually an idiopathic condition (Primary)
Associated with: DM, inflammatory arthritis, trauma,
prolonged immobilization, thyroid disease, CVA, MI, or
autoimmune disease
Stages 1 and 2:
Physical modalities and acupuncture
Anti-inflammatories and analgesics
Intra-articular or subacromial injections
Activity modification
Postural retraining
Therapeutic exercises
(passive and active assisted ROM, isometrics, & CKC)
Stages 3 and 4:
Advanced exercises
Capsular hydrodilatation, manipulation under anesthesia, and
arthroscopic lysis (refractory cases)
Pain is often aggravated by elevation of the arm above shoulder
level or by lying on the shoulder.
Usually calcific deposits visible on X-ray and ultrasound
Treatment
Dietary calcium restriction
Extracorporeal shock wave therapy
Medications
Physical modalities
Injections, needling, and lavage
Corticosteroid injections
Surgery [with high success rates (around 90%) in refractories]
Fibrosis in and around the palmar fascia, with nodule formation
and contracture of the palmar fascia leading to flexion contractures
of the digits (MCP & PIP).
Mostly fourth and fifth fingers
Associated with: age, sex (men),
duration of diabetes, racial and genetic
factors, chronic liver disease
Approximately 16-42% of adult with DM
Risk factors: repetitive handling tasks or vibration, other localized
fibroses, cigarette smoking and alcohol consumption, use of
anticonvulsants
Alarm: malignant neoplasm
Conventional noninvasive treatment
Physical modalities
Splint
Continuous passive traction
Adaptive equipment
Procedures
Fasciotomy with closed needle and collagenase
injections, prolotherapy, steroid injection
Surgery
Nodule formation, pain and locking phenomena.
Mostly the ring finger, middle finger, and thumb
which is typically at the MCP joint with bilateral
involvement.
Approximately 20% of adult with DM
Rest from provocative activities
Local steroid injection (A-1 pulley)
Splint or buddy taping
(for 4 to 6 weeks)
Wearing padded gloves
Physical modalities
NSAIDs
Surgery
(refractory cases )
Painless stiffening of the joints due to
thickening and waxiness the dorsal surface of
the fingers (like Sclerodermia)
The prevalence in DM: 8 to 58%
Associated with: Age, the duration of diabetes,
glycemic level (A1C), cigarette smoking,
microvascular complications.
Good glycemic control
Physical modalities
Passive palmar stretching
Cessation of smoking
Medications
(penicillamine & aminoguanidine)
Overactivity of
the sympathetic nervous
CRPS I (minor or no injury)
CRPS II (causalgia)
Refers to nerve injury
Stage 1: Mild diffuse pain with inflammation
Stage 2: Moderate pain and pallor
Stage 3: Unyielding pain, atrophia, and
contracture
Prevention:
A 50-day regimen of daily vitamin C of at least 500 mg
Treatment:
Medication (pain reduction)
Intensive PT & OT
Acupuncture, HBOT, and
mirror therapy
Neuromodulation
Pain procedures (blocks)
Percutaneous Surgery
The femoral head is the most common
Caused by various conditions, including trauma, high
doses of corticosteroids, alcohol abuse, diabetes, SLE,
and SCA.
Symptoms: similar to hip OA
Physical findings are largely nonspecific.
In earlier stages:
Plain films and MRI can be normal and
abnormal, respectively
In severe cases: Collapse and OA
The treatment of osteonecrosis remains one
of the most controversial subjects
Nonoperative management
Partial WB with crutches, WB as tolerated
Medication
ESWT, electrical stimulation, and
hyperbaric oxygen
pulsed electromagnetic fields
Joint-preserving procedures
Joint replacement
Mostly are primary with positive FH but associated conditions
as secondary RLS including iron deficiency, uremia, NP, DM,
SCI, MS, PD, carcinoma, and pregnancy
Diagnostic criteria for RLS
1. An urge to move the legs
●The urge to move or unpleasant sensations
2. Begin or worsen during periods of rest or inactivity
3. Partially or totally relieved by movement
4. Worse in the evening or night
5. Symptoms are not solely accounted for by another medical or
behavioral condition
Pharmacologic:
For primary RLS (symptomatic)
For secondary disease
(curative possible).
Nonpharmacologic:
Sleep hygiene measures
Avoidance of caffeine, alcohol, and nicotine
Discontinuation some drugs
Exercise
Physical modalities before bedtime
Acupuncture
Uncommon: 0.1% to 0.4%
Typically in longstanding diabetes (>15 years)
Diabetic neuropathic joint disease most commonly affects foot and
ankle, (in contrast to tabes dorsalis and syringomyelia)
The most frequently tarsus and tarsometatarsal joints
The diagnosis should be considered in any patient with diabetes who
presents with a unilateral warm, swollen, erythematous foot, particularly
in the context of peripheral neuropathy and longstanding disease.
Symptoms often milder than view of X-ray.
X-ray:
Subluxation, bone fragment, osteolysis,
periosteal reaction, deformity, ankylosis
Isotope scan and MRI
In the earlier stages (acute therapy):
Offloading [non WB and Total contact cast or patellar tendon-bearing
(PTB) brace and Charcot’s restraint orthotic walker (CROW)]
Prefabricated walking braces or orthosis and wheelchair
Bisphosphonate
Intranasal calcitonin
In the later stages (irreversible):
The goal of treatment: correction of tightness, good
podiatry and specialized footwear and orthoses is to
maintain a stable plantigrade foot that is free of
ulceration and infection
Disease of the hindfoot and ankle appears to have a worse prognosis
than disease of the midfoot.
Surgical correction is best avoided in most patients
Hammer toe: An abnormal flexion posture at the PIP joint of one
or more of the lesser four toes +/- MTP hyperextension
More commonly in women
The most common of the lesser toe deformities
Claw toe: An abnormal flexion
posture at the DIP and PIP joints
Mallet toe: An abnormal flexion
posture at the DIP joint with normal PIP
and MTP
Contributing factors: long-term wear of poorly fitting shoes,
especially those with tight, narrow toe boxes, overlapping from hallux
valgus, a long second ray, diabetes, connective tissue disease, and
trauma
Foot care education
High heel avoidance
Shoes with wide and deep toe box
Stretching and strengthening exercises
Medication
Debridement of calluses
Orthesis
PIP steroid injection
Surgery
Noninflammatory disease, with calcification and ossification of spinal
ligaments and of peripheral entheses.
Radiographic changes +/- musculoskeletal symptoms.
Thoracic spine most commonly affected.
Tolerable pain with morning stiffness in neck and back
Radiographs of the thoracic spine as the initial
diagnostic study
Treatment:
Medication
Physical modalities
Peripheral orthotics and injections
Functional exercise programs
(stretching, strengthening, aerobics with swimming)
Surgery: dysphagia and cervical spinal cord compression, root lesion and
TOS, Horner's syndrome, recurrent laryngeal nerve palsy, and vertebral
artery insufficiency
Hypoglycemic drugs major interactions:
Methylprednisolone: increased blood glucose
Aspirin: decreased blood sugar
Hyperglycemia after steroid injection:
Intra-articular: peak around 48h, can remain up to 5 days
Epidural: may up to 14 days
Thanks For Your Attention