Transcript DRUG LIST #7 - aj pharmacy

DRUG LIST #7
MOD 500
NSAID COX 2 INHIBITOR
 CELEBREX
 CELECOXIB
 INDICATION





RA
OA
inflammation
mild to moderate pain
Additional uses include primary dysmenorrhea, ankylosing
spondylitis, JRA.
 ACTION
 inhibition of cyclooxygenase
 WARNINGS
 black box warning for drug class concerning cardiovascular and
GI risks.
 Take with food
 Avoid alcohol, APAP and ASA
 D/D
 MISC. NOTES
 Drug interactions:
 ASA
 Biphosphonates
 warfarin
NSAIDS
NON STEROIDAL ANTI-INFLAMATORY DRUG
NSAIDS
 VOLTAREN
 DICLOFENAC
 MOTRIN
 IBUPROFEN
 INDOCIN
 INDOMETHACIN
 MOBIC
 MELOXICAM
 RELAFEN
 NABUMETONE
 NAPROSYN
 NAPROXEN
 FELDENE
 PIROXICAM
 INDICATION
 RA, OA, inflammation, mild to moderate pain
 Ibuprofen: also indicated for migraines.
 Indomethacin: also indicated for gouty arthritis
 ACTION
 inhibition of cyclooxygenase (COX-1 and /or COX-2) which
decreases prostaglandin synthesis
 WARNINGS
 black box warning for drug class concerning cardiovascular and GI
risks. Take with food. Avoid alcohol, APAP and ASA. D/D
 INTERACTIONS
 ASA, biphosphonates, warfarin
BONE GROWTH REGULATOR
biphosphonate
 BONIVA
 IBANDRONATE
 ACTONEL
 RISEDRONATE
 INDICATION
 osteoporosis, glucocorticoid induced osteoporosis.
 Risedronate: pagets disease
 ACTION
 inhibit bone reabsorption
 WARNINGS
 Oral use
 tablets should be swallowed whole with 180-240ml of plain water.
Patient is to remain upright for at least 60minutes after dosing. Weekly:
take on same day each week. Monthly: take on same day each month Jan
10th, Feb 10th etc.
 IV use
 must be given intravenously and not intraarterially to avoid tissue
damage. Not to be mixed with other IV medications.
 adequate calcium and vit D intake essential.
 Report signs of esophageal issues.
CORTICOSTEROIDS
 MEDROL/SOLUMEDROL
 METHYLPREDNISOLONE
 STERAPRED
 PREDNISONE
 INDICATION
 rheumatic disorders, replacement therapy, allergic states,
respiratory diseases and others.
 ACTION
 stimulates the adrenal cortex to secrete cortisol
 WARNINGS
 take with food. Take in the morning. Side effects more
prominent with extended use
 INTERACTIONS
 ASA, diuretics, phenytoin(hydantoins)
 ADDITIONAL NOTES
 Dosing: very individual. Lowest possible dose should be used.
ANTIHISTAMINE/ANTIANXIETY
‘first generation’ antihistamine. Atarax-tab, Vistaril-cap
 VISTARIL
 HYDROXYZINE PAMOATE
 ATARAX
 HYDROXYZINE HCL
 INDICATION
 allergic reactions, sedative, motion sickness. Pruritis, sedation,
anxiety and tension
 ACTION
 competes with histamine for H1 receptor sites in GI tract, blood
vessels and respiratory tract
 WARNINGS
 avoid alcohol. D/D, take with water
 ADDITIONAL NOTES
 INTENSIFIES NARCOTICS
ANTIHISTAMINE
2ND GENERATION
 ZYRTEC
 CITIRIZINE
 ALLEGRA
 FEXOFENADINE
 XYZAL
 LEVCITIRIZINE
 INDICATION
 allergic rhinitis, urticaria, hay fever
 WARNING
 less drowsiness than first generation
 ADDITIONAL NOTES
 ZYRTEC OTC
THYROID REPLACEMENT THERAPY
 SYNTHROID/LEVOXYL
 LEVOTHYROXINE
 CYTOMEL
 LIOTHYRONINE
 INDICATION
 HYPOTHYROIDISM
 ACTION
 hormone replacement levothyroxine; T4. liothyronine: T3
 WARNINGS
 several food interactions, antacids, anticoagulants, phenytoin.
 Black box warning: should not be used alone or in combination
with other therapeutic agents for obesity. May cause serious
or life threatening manifestations of toxicity.
ANTITHROID
 TAPAZOLE
 METHIMAZOLE
 INDICATION
 hyperthyroidism, thyrotoxic crisis
 ACTION
 blocks oxidation of iodine, inhibiting the synthesis of T3 and T4.
 WARNINGS
 may cause bone marrow depression. May cause fetal harm.
 Take with food.
 Drug interactions: include digoxin, warfarin