Transcript ATI Neurostimulation system:

ATI
NEUROSTIMULATION
SYSTEM:
Electronic Aspirin
Presentation by:
Sarah Borges
ATI NEUROSTIMULATION SYSTEM
 Known commonly as “Electronic aspirin”
 Only one company developing this device - ATI
 Consists of 2 separate pieces
• Remote control
• Implantable device
 Designed to treat cluster headaches
CLUSTER HEADACHES
 Also known as “suicide” headaches
 Condition of severe unilateral temporal/orbital pain
 Headaches last 15 min-3 hours
 Symptoms include:
•
•
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Watery eyes
Droopy eyelid
Nasal congestion
Localized swelling
 Associated with the SPG (sphenopalatine ganglion) bundle
 Affects 0.2% of United States population
OTHER TREATMENT METHODS
 Oxygen treatment with a tank
• Cumbersome
 Oral medication
• Run the risk of an allergic reaction
 Sphenopalatine ablation
• Killing local SPG area via heat
• Last resort: can lead to partial facial paralysis
ATI SYSTEM DESIGN
 Two separate parts:
• Device
 Almond-sized
 2 terminals
• Remote control
 Hand-held, rechargeable
 Upon onset of headache, patient places
remote to device, sending electrical signal
to device
 Device stimulates SPG bundle in a way that
prevents the release of pain-related
neurotransmitters
IMPLANTATION PROCEDURE
 Surgery is about as extensive as removal of wisdom teeth
• ~1-3 hours in length
 Device is implanted on the side of the head patient experiences
headaches more: within gum tissue, below eye
CURRENT RESULTS
 System still in clinical trial phase
• Currently testing device on 120 patients since
• Will continue monitoring patients for one year
 Preliminary results:
• 75% patients have recorded improvement in their ability to
function normally in their daily lives
• 68% report experiencing less severe headaches
• 31% report a decrease in the amount of headaches they have
weekly
BENEFIT OF ATI SYSTEM OVER
OTHER TREATMENTS
 Less bulky/more conspicuous than an O 2 tank
 Does not risk patient having an allergic reaction or
conflicting prescriptions for other health implications
 Unlike ablation, ATI system has temporary effects
• ATI system can be removed if need be
FORESEEN DISADVANTAGES
 More difficult to stop treatment than O2 tank/oral
medications: need surgery to remove
 Can only treat one side of head
 Have to remember to charge remote control and bring
everywhere
 Electronic device: has the potential to malfunction
 Only treatment for patients of cluster headaches
FUTURE DIRECTION
 FDA approval
 Design to make available to patients suffering from
migraines, tension headaches, and other types of facial
pain due to other conditions they may have
REFERENCES
 Bahra, Anish, et al. "Cluster Headache: A Prospective Clinical Study with
Diagnostic Implications." Neurology58.3 (2012): 354 -61. Neurology. Web.
2 Nov. 2014
 Sphenopalatine Ganglion Stimulation for the Treatment of Chronic
Cluster Headache<http://clinicaltrials.gov/ct2/show/
results/NCT02168764?term=autonomic+technologies>
 Electronic Aspirin <http://www.bibalex.org/psc/en/home/
sciplanetdetails.aspx?id=104>
 Wikipedia: Cluster Headache <http://en.wikipedia.org/wiki
/Cluster_headache>
 Zapping the Sphenopalatine Ganglion
<http://www.clusterattack.com/blog/zapping -the- sphenopalatineganglion/
 "News Europe: Neurostimulation: Gingival Implant Helps Reduce Cluster
Headache." RSS. Dental Tribune International, 6 Mar. 2014. Web. 12 Nov.
2014.
 Hanna, M. "Migraine Headaches, Tension Headaches, and Cluster
Headaches." Dr. M. Hanna, n.d. Web. 10 Nov. 2014.
<http://drmhanna.com/migraine -headaches-tension-headaches-and-clusterheadaches/>.