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Normal Aging, Frailty & Cognition:
Considerations for the ED
Laura J. Y. Wilding RN BScN MHS ENC(C)
Advanced Practice Nurse
Geriatric Emergency Management
The Ottawa Hospital &
The Regional Geriatric Program of Eastern Ontario
September 2013
Geriatric Emergency Management
What are we trying to accomplish?
Target high-risk seniors discharged home from the ED
Advocate for age-appropriate care
Improve the quality & sustainability of ED discharges
through early referral to specialized geriatric services &
community support services
Integration of acute care, primary care & community care
Support the capacity for older adults to remain safely in
their own home
Normal Changes of Ageing
Older adults have unique physiological,
medical and social requirements that must be
considered during their ED evaluation.
Normal Changes of Ageing
Happen to 100% of the population
Increase complexity
Increase risk of injury
Contribute to atypical presentation
Increase risk for a negative outcome
Myths & misperceptions?
Normal Changes of Ageing
Frailty
A physiologic syndrome characterized by
decreased reserve & resistance to stressors,
resulting from cumulative decline across
multiple physiologic systems, causing
increased vulnerability to adverse outcomes.
Fried et al. 2001
Model of Frailty
De Witte et al, 2013, adapted from Gobbins et al, 2010
Frailty
Multifaceted syndrome
Combination of multiple co-morbidity, decreased
physiological reserve & decreased functional
capacity
It’s the opposite of health, successful ageing
Physical, social & emotional
It’s not normal & it’s not a good thing…
Frailty
Malnutrition; Weight loss
Impaired physical function
Weariness
Low exercise tolerance
Low level of physical activity
Possible cognitive impairment &/or
depression
Geriatric Assessment for the ED
Medical Hx
Cognition
Mood
Mobility
Pain
Functional Assessment
(ADL & IADL)
Medication review
Nutrition
Continence
Social Hx
Cognitive Assessment in the ED?
Assess acute status
Medical clearance
Change to baseline
Appropriate education &
safe discharge planning
Opportunity for early
intervention & follow-up
Considerations for the ED
Goal
Medical status
Environment
Considerations for the ED
Acute Illness
Baseline
Acute change?
Risk Factors
Presenting complaint
Collateral history
Screening Tool
Pain
Anxiety
Fatigue
Inadequate or missing
sensory aids
Appropriate space, privacy,
lighting
Spectrum of Cognitive Change
Normal
Changes of
Aging
Mild
Cognitive
Impairment
Dementia
Lee, 2013
Normal Changes of Ageing: Cognition
Normal
Changes of
Aging
Mild
Cognitive
Impairment
Decreased # brain/nerve cells
Decreased neuron function
Benign forgetfulness
Memory change
Changes to sleep patterns
Dementia
Mild Cognitive Impairment
Normal
Changes of
Aging
Mild
Cognitive
Impairment
Dementia
10 - 15% of seniors
Impaired memory when compared to others of same age &
education but function well
Borderline
Many convert to dementia
Must r/o other cause such as depression, drugs, disease
Need close follow-up
Dementia
Normal
Changes of
Aging
Mild
Cognitive
Impairment
Dementia
Gradual but continuous change in cognition that
is seen over time
Accompanied by a change in function
Not due to other reversible cause
BC Guidelines:
Recommendation 1 - Recognition
1 (b) Cognitive impairment should be suspected when there
is a history that suggests a decline in occupational, social
or day-to-day functional status. This may be directly
observed or reported by the patient, concerned family
members, friends and/or caregivers.
Clinical Features: ABC
B = Behaviour
A = ADL’s
Anger
Bathing, grooming, toileting
Irritability
Finances
Apathy
Shopping
Depression
Driving
Agitation
Cooking
Medication management
Laundry
C = Cognition
Forgetfulness
Repetitive questions/stories
Word finding problems
Planning meals/shopping
Misplacing objects/getting lost
Symptoms of Cognitive Impairment:
ADL/IADLs
Gets lost in own
neighbourhood & doesn’t
know how to get home
Dresses inappropriately
(e.g. may wear summer
clothing on a winter day)
Trouble managing
finances
Computer & telephone use
Food preparation/cooking
Ability to deal with
emergencies
Medication management
Transportation
Home maintenance
Housekeeping/laundry
Ability to carry out
hobbies
Symptoms of Cognitive Impairment:
Behaviour
Repeatedly forgets where things are left; put things in
inappropriate places
Has mood swings for no apparent reason & especially
without prior psychiatric history
Has dramatic personality changes; may become
suspicious, withdrawn, apathetic, fearful or
inappropriately intrusive, over familiar or disinhibited
Becomes very passive & requires prompting to become
involved
Symptoms of Cognitive Impairment:
Cognition
Asks the same question repeatedly
Cannot remember recent events
Cannot prepare any part of a meal or may forget that they
have eaten
Forgets simple words, or forgets what certain objects are
called
10 Behavioural Flags:
Office, ED or Hospital
1.
2.
Frequent hospitalizations or visits to emergency department
Poor historian, vague, seems “off,” repetitive questions and/or
stories
3. Poor understanding or compliance with medications and/or
instructions
4. Appearance/mood/personality/behaviour
5. Word-finding problems / decreased social interaction
6. Subacute change in function without clear explanation
7. Confusion
8. Weight loss, dwindles, “failure to thrive”
9. Driving: collision/problems/tickets/family concerns
10. + Head-turning sign
Types of Dementia
Alzheimer’s Type
Vascular
Lewy-Body
Frontal-Temporal
NPH
Alzheimer’s Type
Gradual onset
Slow progression
Dominated by problems with memory & orientation
Aphasia, apraxia, agnosia
** If your patient has an abrupt onset, rapid progression and
is not dominated by problems with memory & orientation
this is a red flag for other dementias
Vascular
Pure Vascular dementia is relatively uncommon - most are
mixed with AD
Gait disturbance
Unsteady, falls, urinary incontinence
Personality, mood & executive function change
Lewy Body
Triad of symptoms:
Fluctuation in cognition
Recurrent visual hallucinations - well formed detailed non
threatening
Motor features of parkinsonism appears at the time of
dementia
Frontotemporal
Neurodegenerative disease primarily affecting the
temporal & frontal lobes
Early decline in social interpersonal conduct
Social disinhibition, loss of insight
Impulsive
Emotional blunting: loss of warmth
Men in 50’s
Normopressure hydrocephalus
Triad of symptoms:
Gait difficulties
Urinary incontinence
Mental decline
wet, wobbly & wacky
Frequently misdiagnosed as Parkinson's disease
Stage @ Time of Diagnosis
Benefits of Early Diagnosis
Medical
Social
Social/financial planning
Early caregiver education
Safety: driving, cooking,
smoking, compliance
Advance directives planning
Right/Need to know
Reversible cause/component
Risk factor treatment
Compliance strategies
Optimization of
comorbidities
AChEI treatment
Crisis avoidance
31
Delirium
A disturbance of consciousness
with inattention that develops
over a short time & fluctuates
Delirium: Specific ED Literature
What do we know?
Common in ED patients
We’re not very good at identifying patients with
delirium (Lewis et al 1995; Eelie el al. 2000)
May not get recognized even when the patient is
admitted (Han, 2009)
When it’s missed in the ED the outcomes are poor
(Han, 2010; Kakura 2003)
Use of a validated tool improves the identification of
delirium
Delirium vs. Dementia
Delirium
Dementia
Onset
Abrupt confusional state that is
different than their baseline;
acute, potentially reversible
Gradual progressive decline
over time; chronic,
irreversible
Awareness
Reduced awareness of their
environment
Clear
Alertness
Fluctuates; can be hyper vigilant
or lethargic
Generally normal
Attention
Impaired; unfocussed
Generally normal, may
progress over time
Orientation
May fluctuate but can be
“A & O x 3”
Decreases over time
Delusions,
Hallucinations
New onset of delusions or
hallucinations common
Generally with late stage
disease
Cognitive Screening Toolbox….
Ottawa 3DY
CAM
MMSE
MoCA
TICs
Quick Dementia Screen
Mini-cog
Clock Drawing Test
35
Screening Confusion in the ED:
The Champlain GEM Algorithm
NO
Evidence of
acute
change
Administer
M ini Cog/Dementia
Quick Screen
NEGATIVE
END SCREEN
ABC
Concerns
ABSENT:
End Screen
Suspicion of
Confusion and/or
Cognitive
Impairment?
Obtain a history
and baseline from
the patient and
collateral source.
Is this confusion
acute, chronic or
acute on chronic?
CAM
POSITIVE
Assess for
presence of
early warning
symptoms:
ABC concerns
ABC
Concerns
PRESENT:
Further
assessment is
indicated.
NEGATIVE
Administer
CAM
CAM POSITIVE:
Delirium
Suspected
YES evidence
of acute
change from
baseline
Consult back with ED
M D and team:
- Identify potential
cause(s) of delirium
- Identify severity
- Identify level of
safe support in the
home
Suggest
admission
for workup
and
treatment
D/C to
supportive
environment
with a clear
follow-up plan
Refer to SGS
Confusion Assessment Method
Acute onset of a change in
normal mental status &
fluctuating course?
AND
Inattention?
AND EITHER
Disorganized thinking?
OR
Altered Level of Consciousness?
37
Ottawa 3DY
Question
Score
What is the date?
1
What day of the week
is it?
1
Spell the word WORLD
backwards: DLROW
1
(if all correct)
What year is it?
1
Total:
4
Molnar, F.J., Wells, G.A., McDowell, I. The derivation and validation of the Ottawa 3D
and 3DY three and four question screens for cognitive impairment. Clinical Medicine:
Geriatrics. 2008; 2: 1 -11.
Wilding, L., Stiell, I., Molnar, F., O'Brien, J., Moors, J., & Dalziel, W.B. Assessing
cognition in the emergency department: Prospective validation of the Ottawa 3DY case
finding tool with animal fluency test. CJEM. 2011;13(3): 173-226. (Abstract)
38
Medical Workup
Anyone who presents with a change from their
baseline cognition requires a full medical
evaluation:
Bloodwork
Urine R&M, C&S
ECG
CXR
CT head
Also consider:
O2 sat; ABG
Blood cultures
Drug levels
ETOH
Pre-printed
Delirium
Orders
Nursing Interventions:
Prevention & Treatment
Provide adequate fluids &
nutrition
Treat pain on a regular
schedule
Mobilize
Remove all unnecessary
tubes
Give regular medications &
adjust ED meds as
appropriate
Avoid restraints
Regular toileting
Offer eyeglasses, hearing aids
Orient the patient
Speak slowly & clearly, use
short simple instructions
Comfort & reassurance
Family presence**
Good Nursing Care is Key!
Behavioural & Psychological Symptoms of
Dementia (BPSD)
2/3 of people living with dementia will have clinically
significant behavioural issues
Addressing behaviour depends on the characteristic
(what are they doing?), context (when?), frequency,
severity & impact
Behavioural issues significantly impact caregiver
burden
Managing Behaviour
What is triggering the behaviour?
Decrease stimulii
Speak in a calm reassuring voice; speak slowly, clearly
& allow time for the person to respond
Use reassurance & distraction
Gentle physical touch
Do not reason with the person
For repetitive movements – provide something for the
patient to do
Discharge?
Assess for home safety
Driving, smoking, cooking on the stove
Managing medications
Behaviour
Adequate supervision
Extra Supports?
Consider SW, CCAC, PT, BSO
Education: patient & family
Appropriate follow-up: GP, SGS