Transcript Introduction - Farmasi Unand

Pengembangan Farmasi
Veteriner
RINI AGUSTIN , M.Si,Apt
INTRODUCTION




Animal provide us with companionship, recreation,
food and animal labor
Just like human these animal receive medicine to
keep them healthy
Drugs have been compounded for veterinary
practise for many years but regulation and
compliance policy Guidelines (CPG) should be
recognized
A CPG issued in July 2003 listed the current FDA
limitation on compounding for veterinary medicine
Introduction

Compounding can be characterized as any manipulation
to produce a dosage form other than manipulations that
is provide for in the directions for use on the labeling of
an approved drug product. This is to say that mixing a
pediatric liquid antibiotic is not compounding, but making
a sterile inject able from non-sterile materials is the most
difficult form of compounding.
Introduction

Compounding should be the ultimate expression of
Pharmaceutical Care. In order to practice good
Veterinary Pharmaceutical Care the individual will
have to broaden his/her skills beyond human
pharmacology. The diversity of issues involved
with the myriad of species requiring pharmaceutical
interventions is legend.
Introduction

Using the ADME model in human patients requires the practitioner to investigate each
step as a consequence of multiple pathologies, using the same model in the veterinary
population requires an understanding of the species-specific anatomy, physiology, biochemistry, velocity of metabolism to name just a few confounds
Introduction

The office based vet is a recent phenomenon. Historically
veterinarians necessarily dispensed medications from their own
dispensary. Classically the vet traveled from farm to farm plying
their skills which involved not only diagnostics but also creating
dosage forms out of readily available materials. To this day the
pharmaceutical industry pays vague lip-service to the veterinarian
industry.
Introduction

The research and development costs involved with
bringing a veterinary new drug to the market-place
sometimes exceed the cost of bringing the very
same drug to the human market-place. As a matter
of course, there are several exotic species with no
approved drug. This yields a very fertile field for
cultivation by an appropriately trained pharmacist.
Introduction

The fundamental relationship in veterinary compounding pharmacy is the
Patient-Physician-Pharmacist triad. The addition of the owner can complicate
the triad or it can facilitate providing good Pharmaceutical Care. We have
seen the complications that the inter-net has created in human medicine, one
can expect the same uneducated and sometimes dangerous interventions in
veterinary medicine. It is the responsibility of each of us to ensure that our
patients will receive the best that our profession provides to the human
population
Compounding can be characterized
as any manipulation to produce a
dosage form other than manipulations
that is provide for in the directions for
use on the labeling of an approved
drug product.
Regulation in Indonesia

PERATURAN PEMERINTAH REPUBLIK INDONESIA NOMOR 78
TAHUN 1992 TENTANG OBAT HEWAN

PERATURAN MENTERI PERTANIAN NOMOR
74/Permentan/OT.140/12/2007 TENTANG PENGAWASAN OBAT
HEWAN

PERATURAN MENTERI PERTANIAN NOMOR
18/Permentan/OT.140/4/2009 TENTANG SYARAT DAN TATA CARA
PEMBERIAN IZIN USAHA OBAT HEWAN

PERATURAN MENTERI KESEHATAN NOMOR 466 TAHUN 1999
TENTANG CPOBH
Organisasi Terkait di Indonesia
Affaveti (asosiasi Farmakologi dan
Farmasi Veteriner Indonesia)
 ASOHI (Asosiasi Obat Hewan Indonesia
 Bbpmsoh (balai besar pengujian mutu
dan sertifikasi obat hewan )

Interaction with Vets

You are the drug experts!
 Logic Disconnect: Who knows?

You don’t know everything, get a book

Just because you can do it, doesn’t mean
you should.

Vets are really nice people
Interaction with Vets

Vet Techs are the gate keeper.
 Vet techs can be your best friends.
 Vet techs can be your worst nightmare.
 Vet techs want to learn.
 Receptionists are not Vet Techs
 Some Vet techs are not Vet techs
 Some “nurses” are vet techs, some nurses
are nurses and some nurses aren’t .
Interaction with Vets

Clients are the owners, patients are the animals

SID means once a day, don’t argue you won’t win.

The pharmacological argument. Win, lose or draw.

Don’t mess it up for the rest of us

Just say No.
The Patients/Clients

The patient is the animal, the client is the
owner/guardian.

Large Animals /Food Animals/ Zoo animals
 Probably not the best place to start..
 Dr. Midnight Milk Cup
 The squirt gun approach
The Patients/Clients

Companion Animals
 You wouldn’t believe what some people have as pets.
Aardvarks to zebras, really.
 Gerbils, turtles, snakes, butterflies, lizards, large
predator cats, elephants, ennui’s, swans, storks,
flamingoes, fish, frogs, goats, pigs, foxes, hedgehogs,
wolves, foxes,
The Patients/Clients

Canine
 There are many breeds but they are all canines.
 There are many genetic specific predominant.
 The new pocket breeds are fraught with genetic





problems
Dogs eat rocks
Idiopathic Canine Epilepsy
Thunderstorm Phobias
Dry Eye
Ear Grunge
The Patients/Clients

Feline
 Cats are finicky, prissy, compulsive, passive






aggressive.
Pilling cats ain’t fun
You can trick them a couple of times, but plan on
them catching on.
Mega colon
Hyperthyroidism
Hypertensive
Psychotic
The Patients/Clients

Compounded Companion Animal Dosage Forms
 Tablet Triturates
 Flavored Liquids
 Treats
 Transdermals
 Flavored pastes
 Capsules
Resources and References






Veterinary Information Network
A great reference source and a place to interact with
vets. You will need to have a vet sponsor and probably
will have to advertise.
http://vin.com/
Plumb’s
This is the ubiquitous green book. (although it’s red now)
This is the definitive handbook on veterinary
pharmaceutics. It can be accessed via VIN.
Plumb's Veterinary Drug Handbook, Fifth Edition,
Donald C. Plumb
Resources and References





Mc Gavin’s
This is the Depiro of veterinary pharmacology. Great
basic book. The fourth edition is current.
Pathologic Basis of Veterinary Disease, Fourth Edition,
Mc Gavin, Donald etal. Moby.
ACVP
The pre-eminent society of Veterinary Pharmacists. The
put out a newsletter on a regular basis. They also have a
Dear Doc letter that can be used in marketing your
practice.