IV THERAPY - wbpracnsg.com
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IV THERAPY
PART I
Catherine Luksic BSN,RN
WHAT IS IV THERAPY ?
Intravenous – into the vein
Administration of substances (fluids) directly into
the vein
Parenteral route
PN SCOPE OF PRACTICE:
IV THERAPY
State of Pennsylvania – requirements
Satisfactory completion of Board approved IV therapy
course
LPN complies w/ policies/procedures of institution
Review of policies/procedures q 12 mos.
Functions of PN
Perform venipuncture
Administer IV fluids
May NOT administer:
Antineoplastic agents
Blood products
Titrated medications
IV push medications
**As of 7/2012 – LPN may
administer & maintain
TPN, lipids
PN SCOPE OF PRACTICE: RULES AND
REGULATIONS
Refer to Handout
LEGAL ISSUES
Informed Consent
Pt. has right to refuse treatment
If pt. is incompetent or unable to give consent, legally
authorized rep. may consent
Coercion of rational adult patient to place an IV
catheter constitutes assault & battery
Nurse must comply w/ acceptable nursing
standards established by facility, as well as
state/federal guidelines
Manual of IV Therapeutics, Phillips, 2010
Infusion equipment, administration of meds,
monitoring of pt., documentation, etc.
If an act of malpractice causes harm, legal action
can be initiated
INDICATIONS FOR IV THERAPY
Fluid & Electrolytes
Maintenance
Replacement – fluid or electrolyte deficit
Restoration - ongoing losses. (i.e. drains, NGT’s,
severe diarrhea, vomiting, burns)
Medications
Nutrients
antibiotics, potassium, insulin, heparin, etc.
TPN, PPN
Blood Products
PRBC’s, FFP, Platelets
ADVANTAGES OF IV THERAPY
1. Bioavailability is immediate
Drug enters circulation immediately, permits access to
site of action
2. Absorption into bloodstream is complete and
reliable
3. Large doses can be delivered at a continuous
rate
4. No “first pass” effect in the liver
DISADVANTAGES OF IV THERAPY
1. Adverse reactions may occur – can be life
threatening
If medication administered too quickly
Allergic reaction
2. Increased risk of complications
Extravasation
Vein irritation (phlebitis)
Systemic infection
Air embolism
THE HEART
BLOOD VESSELS
Arteries - carry blood away from heart. Branch
off into smaller arteries eventually into
capillaries.
OXYGENATED BLOOD
Veins - blood from capillaries flow into veins,
carry blood back to the heart
UNOXYGENATED BLOOD
BLOOD VESSEL WALLS
Tunica intima - innermost layer. Continuous with
the endocardium.
Tunica media - middle layer. Smooth muscle and
elastic tissue.
Tunica adventicia (externa) - tough outer layer.
BLOOD VESSEL WALLS
BLOOD VESSEL WALLS
ARTERIES VS. VEINS
Middle layer (tunica media) much thicker in
artery
Arteries contract & relax
Due to high pressure and thicker muscle layer
Pressure much less within veins.
Veins have one-way valves to direct blood flow
toward the heart.
Veins store blood (70% of blood volume).
ARTERIES:
Thick wall (tunica
media)
Lacks valves
Pulsates
Bright red blood
High pressure
VEINS:
Thin wall
valves present approx.
every 3 in.
No pulsation
Dark red blood
Lower pressure
*pulsation may be
seen in jugular vein
VEINS
VEINS
Used for IV therapy
Peripheral (arms/hands):
Cephalic (upper and lower)
Basilic
Median (antecubital)
Metacarpal *First choice for site selection
*allows for increased mobility
*less risk of phlebitis
(Burton textbook recommends forearm veins – to avoid
nerve/tendon damage in hands ???)
PERIPHERAL VEINS – UPPER EXTREMITY
FACTORS TO CONSIDER
Adipose
Edema
tissue
Color
? Adequate tissue perfusion
? Dehydration, volume overload, normovolemic
Avoid these areas
? Lack of, can pt. feel “pain”
Hydration
Tissue
elasticity
Bruising, rashes, breaks in skin
Sensation
VEINS
Refer to handout: Veins
Practice identification of peripheral veins in
classroom
Learn to properly apply tourniquet to upper
extremities
VENOSCOPE: VEIN FINDER
IV ACCESS
Peripheral - Located in peripheral veins of
upper (and sometimes lower) extremities
Can be placed by nursing (qualified LPN’s & RN’s)
Central - Located in large vessels near heart (ie,
subclavian, internal jugular, femoral)
Can only be placed by physician or specially trained
practitioners
PERIPHERAL IV
Smaller vessels
Slower blood flow
Easy access
Veins of hands, arms most commonly used
Metacarpal, cephalic, basilic, accessory cephalic,
median, upper cephalic
Needs to be changed regularly
Every 48-72 hours, according
to policy
2011 Infusion Nursing Standards of Practice –
rotate peripheral IV catheters based on clinical
condition vs. set time frame
CENTRAL IV ACCESS
Higher risk of life-threatening complications
Larger vessels
More turbulent blood flow
Care includes sterile dressing changes and
flushes
Used if peripheral access not possible, or for
long-term use.
Percutaneous, tunneled, or implanted.
Includes PICC lines (peripherally inserted
central catheter)
CENTRAL IV LINES
Usually located in subclavian vein, jugular vein
Can also have access through cephalic, basilic,
antecubital and axillary veins
PICC lines
PICC LINE
CENTRAL IV LINE
CENTRAL IV LINE
IV SOLUTIONS
Bottle vs. Bag
Types of Solutions
Tonicity
Electrolyte Solutions
SOLUTION CONTAINERS
Bottle - Not commonly used
Meds that cannot be in plastic
Advantages: Very easy to visualize solution and to
see calibrations
Disadvantages: BREAKS. Easier to contaminate.
Takes more storage space.
Examples: Nitroglycerin, Albumin, Lipids
Lipids are also stable in special plastic
Requires tubing w/ vent
IV BOTTLE
SOLUTION CONTAINERS
Plastic - Most common container
Atmospheric pressure collapses bag , forces fluid out.
Advantages: Easy to store. Not greatly affected by
temp fluctuations.
Disadvantages: Can be punctured. Some meds can
adhere to plastic.
**ALWAYS inspect bag/bottle before
use
TYPES OF SOLUTIONS
Colloids - Pulls fluid into intravascular space, volume
expanders
Albumin – treat low BP/shock, provides protein
Dextran – to prevent venous thrombosis during OR
Hespan (hetastarch)
Considered to be a blood product
Similar to albumin
Crystalloids - Used for hydration, most common **
Saline, Dextrose
TYPES OF SOLUTIONS
Blood and blood products
Restore blood volume or components
PRBC’s – acute blood loss, anemia Hg <8.0
FFP – replace coag factors, will reverse effect of
coumadin (PT/INR elevated)
Platelets – thrombocytopenia, control bleeding
Whole blood – rarely used, restores blood volume
LPN cannot admin. but can monitor pt. during
infusion
Beware of transfusion reaction
TYPES OF SOLUTIONS:
BLOOD PRODUCTS
Physician order & consent required
Type and crossmatch required (ABO type, Rh
group)
Only compatible with 0.9% NS **
Dextrose can cause hemolysis
Frequent VS, monitor pt. continuously for first
15 min.
2 RN’s must check blood product before
initiating infusion
TYPES OF SOLUTIONS
Transfusion Reactions
1. Hemolytic: DANGEROUS, RBC’s attacked by
immune system – cells burst
Bleeding (urine), chest pain, back pain, low BP, chills
May be a delayed reaction, usually immediate
2. Febrile:
3. Allergic
Itching, SOB, wheezing, possible rash
4. Anaphylaxis: DANGEROUS
N/V, fever, chills, headache, chest pain
Wheezing/stridor, SOB, low BP, cyanosis, anxiety
5. Circulatory Overload
Low SP02, tachycardia, high BP, dyspnea
ALWAYS STOP THE TRANSFUSION IMMEDIATELY
IV NUTRITIONAL SUPPORT
TPN – Total Parenteral Nutrition: IV infusion of
amino acids, vitamins, electrolytes, and minerals
Usually high dextrose concentration
Used when GI system cannot be used for feeding
LPN can administer **
High dextrose concentration (>10%) can damage veins,
usually given via central vein
Intralipids - intravenous infusion of fat (fatty
acids)
essential fatty acid is linoleic acid, needed for proper
metabolism.
IV lipids are “white”
Lipids can be “piggybacked” with TPN
IV NUTRITIONAL SUPPORT
Increased
dextrose level of TPN can lead
to increased microbial growth
TPN & LIPIDS
FLUID COMPARTMENTS IN THE BODY
Intracellular :
fluid inside cells of the body
High concentrations of potassium(K+), phosphate,
and magnesium ions
2/3 of body water
Extracellular:
fluids outside cells
Includes interstitial & intravascular compartments
Contains high concentrations of sodium, chloride, and
bicarbonate ions
1/3 of body water
ELECTROLYTES
Sodium (Na+)
Major extracellular cation
Normal 135-145 meq/L
Calcium (Ca+) – extracellular cation
Chloride (Cl-)
Major extracellular anion
Bicarbonate (HCO3) – extracellular
Magnesium (Mg+) – intracellular cation
Potassium (K+)
Major intracellular cation
Normal 3.5-5.0
Hyperkalemia = serious danger !
IV SOLUTIONS
Osmosis: regulates fluid & electrolyte balance =
movement of water through SPM from area of
lower concentration (solutes) to higher
concentration
SPM’s = tunica intima, capillary walls, and cell
membranes of RBC’s
Rate of osmosis – depends on osmotic pressure within
tissues/cells
Draws water through SPM to more concentrated area
IN or OUT of cell
IV SOLUTIONS
Tonicity = osmolarity or concentration of IV
solution
Amount of solute in a fluid (dextrose, sodium, etc.)
ISOTONIC: concentration same as blood
No osmosis
No change in solute or water in blood, no shrink or swell
Increases amount of ECF
Caution w/ fluid volume overload (CHF, renal patients)
Uses: replace fluid loss, dehydration, to administer
IVPB
0.9% NS, LR, D5%W
ISOTONIC SOLUTIONS
IV SOLUTIONS
HYPERTONIC: Higher concentration of
solutes
Osmosis pulls water out of cells
Fluid shifts from intracellular > intravascular
Increased fluid volume in vascular space
CAUTION with CHF patients
May raise BP
May irritate the vein walls
Cells shrink
Can cause “cellular dehydration”, cellular death
Uses: dehydration, electrolyte replacement
(severe), expand blood volume
D5LR, D5 0.9% NS, D5 0.45% NS, D10%, albumin,
dextran
HYPERTONIC SOLUTIONS
IV SOLUTIONS
HYPOTONIC: Lower concentration of solutes
Osmosis pushes water into cell
Fluid shifts from intravascular > interstitial >
intracellular
Cell is re-hydrated
Cells swell, can possibly “burst” – hemolysis
Uses: DKA
Can cause intravascular fluid depletion – caution !
May cause hypotension
Can increase ICP from quick fluid shift
Cerebral edema
0.45% NS, 0.3% NS, 0.25% NS
HYPOTONIC SOLUTIONS
IV SOLUTIONS
ISOTONIC
HYPERTONIC
HYPOTONIC
No osmosis; no shift
Osmosis pulls water
out of cell; “raisin”
Osmosis pushes
water into cell;
“grape”
Uses: dehydration,
fluid loss, commonly
used for IVPB
Uses: dehydration,
electrolyte
replacement (severe)
Uses: DKA, cellular
re-hydration, can
replace daily NaCl
requirement
Caution: fluid
volume overload
(cardiac, renal)
Cautions: fluid
volume overload,
hypertension, vein
irritiation
Caution: hemolysis
of cells, intravascular
volume depletion,
hypotension, cerebral
edema
0.9% NS, LR, D5%W
D5 0.9% NS,
D5 045% NS, D5 LR,
D 10%, Albumin
0.45% NS, 0.3% NS,
0.25 % NS
NORMAL SALINE
0.9% NS
Isotonic – osmo same as blood
NaCl = sodium chloride
Non-caloric
Standard “flush” solution
Standard hydrating solution
0.45% NS (1/2) is hypotonic
Lower osmo, less concentrated
SALINE
Saline
- “NS” or “NaCl”
.9% (is isotonic)
.45% is ½
(is hypotonic)
When mixed with D5 may become
hypertonic - MUST WATCH FOR
FLUID OVERLOAD
More fluid in intravascular space
DEXTROSE
Contains
dextrose and free water
Available in a variety of concentrations, 5%
most common.
5% (D5W) is isotonic.
Usually in mixture with NS; D5W alone can
cause severe hyponatremia, hypokalemia, and
water intoxication.
Dilutes body’s normal level of electrolytes
NOT 1st choice for hydration
Cannot
be administered w/ blood
hemolysis
DEXTROSE
Dextrose
usually
- “D”
5%
Also 10%, 20% (usually TPN only –
hypertonic)
provides
calories
D5 = 170 cal/liter
cannot
D10 = 340 cal/liter
be used with blood, certain
meds
Check compatibility
can
affect blood glucose
monitor DM
ELECTROLYTE SOLUTIONS
Usually
isotonic solutions that contain
electrolytes in concentrations similar to
plasma
Lactated Ringer’s most common
contains potassium, sodium, chloride, and
calcium. Lactate added as buffer
Ringers solution = no lactate added
short-term
use (48 hours)
used for fluid loss (vomiting, diarrhea)
Electrolyte replacement
ELECTROLYTE SOLUTIONS
Electrolyte
solutions
Ringer’s or Lactated Ringer’s (LR)
provides electrolytes and hydration
short-term
monitor ELECTROLYTES
no calories
cannot use lactate if liver disease
present – cannot metabolize
ELECTROLYTE SOLUTIONS
Plasmalyte
Multiple combination
Dextrose
Sodium chloride
Sodium acetate
Sodium gluconate
Potassium chloride
Magnesium Chloride
IV THERAPY: ABBREVIATIONS
D5W
0.9% NS
NS = 0.9%
½ NS = 0.45%
(5% dextrose solution
¼ NS = 0.225%
D5
w/ 0.9% normal saline)
D5
0.45% NS
(referred to as D5 ½ NS)
D5 0.45% NS @ 50 cc/hr
D5 ½ NS @ 50 ml/hr
IV THERAPY: ABBREVIATIONS
PICC
POC
TLC
HL
SL
KCL (meq)
CaGluc
MgSO4
TYPES OF IV INFUSIONS
Continuous
rate
– not interrupted, ordered
Intermittent
- access for infusions that
are only given at specific times
IV antibiotics
IV
push - meds that are given all at
once. Not given by LPN’s
with exception of saline flush.
IV PUSH
Meds NOT administered by LPN’s
Must be given by RN
Delivery is immediate
Saline
flush (non-med) – 3-10 mL given
directly into IV to maintain patency.
CAN
IVP
be given by LPN
INTERMITTENT INFUSIONS
Not
continuous
“Piggy-back” meds (IVPB) - intermittent
infusions given through continuous
primary IV line.
ie; IV antibiotics, IV potassium
Check compatability between “piggyback”
and continuous IV solution
Call Pharmacy re: drug-drug interactions
Use on-line resources
Use IV compatibility chart
Incompatible drugs can cause a precipitate
CONTINUOUS IV INFUSION
Can be large volume (250 to 1000cc) of solution
administered continuously
correct or maintain fluid and electrolyte balance.
Can be a medication being delivered on a
continuous basis
to maintain a constant serum level – ie; heparin,
insulin
Needs to be infused with IV pump to avoid error
Continuous IV medications cannot be titrated
(regulated) by LPN’s – must be done by RN