Transcript homeostasis

Characteristics of Life
 Organisms
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respond to their environment
Organisms respond to their EXTERNAL
environment
Organisms respond to their INTERNAL environment
The Human Body
 Human
require many systems for digestion,
respiration, reproduction, circulation,
excretion, movement, coordination, &
immunity
 The components of the human body, from
organ systems to cell organelles, interact to
maintain homeostasis.
What is Homeostasis?
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The maintenance of a constant environment in
the body… BALANCE
 Achieved by many different internal controls
mechanisms that detect deviations and make
corrective actions.
 If there is a disruption in any human body system
there may be a corresponding disruption in
homeostasis
Homeostasis
Conditions within the body must remain within a
narrow range – like your body temperature
Homeostasis involves keeping the internal
environment within set ranges
Control systems help maintain homeostasis.
1. sensors gather data
pore
sweat
glands
2. control center receives
data, sends messages
3. communication system
delivers messages to target
organs, tissues
4. targets respond to change
hair
follicle
muscle
goose
bump
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Why Homeostasis?
Body cells work best if they have the correct environmen
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Temperature
Water levels
Glucose concentration
Your body has mechanisms to keep the cells in a
constant environment OR Dynamic Equilibrium
(balanced, but fluctuates)
Homeostasis
In order to maintain homeostasis the body
uses feedback loops. There are 2 types of
feedback loops:
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Negative Feedback Loop
Positive Feedback Loop
Negative Feedback
It is a process by which a receptor, an integrator
and an effector detects processes and responds
to a change in a body constant so that a reverse
affect takes place.
Negative feedback is when the response takes
the system BACK TO “NORMAL”
This allows the body to stay constant (maintain
homeostasis)
Negative Feedback
Homeostasis Lab
Lab Group of 4
Examples of Homeostasis & Negative
Feedback Mechanisms
1.
2.
3.
4.
Temperature Regulation
Regulation of Blood Sugar
Levels
pH Balance
……and remember the stomates
and guard cells in plants
Negative Feed Back: Human Body Temperature Regulatio
Humans maintain a relatively constant body
temperature of about 37° C.
•when we "heat up" we sweat if possible
•the evaporation of this perspiration returns the
body to its original temperature
Receptor Proteins
•Receptor Proteins are the 1st part of a feedback
loop, and are found in every cell, in every organ &
tissue.
•Send nerve impulses to brain as a result of
environmental stimulants.
•For example: receptor proteins on skin cells
detect changes in temperature and send that
information to the brain.
•If nerve or hormone signal are blocked, cellular
communication is disrupted and homeostasis is
affected.
Outside Cell
Receptor
Protein
Inside Cell
Cell
Membrane
Integrator (The Brain)
•2nd part of negative
feedback loop
•Sends messages to
glands, muscles and/or
organs
•The brain receives
information from the
receptor proteins and
sends a message to
either the sweat glands
or the muscle cells.
Effector (part of the body)
•3rd part of negative
feedback loop.
•Receptor proteins
receive info from brain
causing a change in
internal conditions.
•Sweat glands enable
the body to cool off
when they produce
sweat and muscle
cells enable the body
to warm up when they
Hair follicle
1 - Sweat gland
2 - Sebaceous gland
3- Muscle
3
RECEPTOR PROTEINS
( ON CELLS)
EFFECTORS
(PARTS OF BODY)
RESPONSE=SWEAT
Heat
Gained
Heat
Lost
INTEGRATOR
(BRAIN)
EFFECTORS
(PARTS OF BODY)
RESPONSE =
SHIVERING
Negative Feedback Loop:
Home heating system

Thermostat is set at a desired temp.
 Furnace turns on and heats the house to desired
temp
 When desired temp is reached the furnace turns
off.
 The house cools & temp drops below the
desired temp. the furnace turns on & the house
warms back up to desired temp.
Negative Feedback Controlling
Glucose Levels

Your cells also need an exact level of glucose in
the blood.
 Excess glucose gets turned into glycogen in the
liver
 This is regulated by 2 hormones (chemicals)
from the pancreas called:
Insulin
Glucagon
Increase in Blood Glucose Level
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After eating blood glucose
level increases
Brain sends message to
pancreas to release insulin
into blood
Insulin allows body cells to
absorb glucose
Insulin also stimulates the
liver to convert some
glucose into glycogen ( a
form of stored energy)
The result…..blood glucose
level decreases &
homeostasis occurs.
Glycogen
If there is too
much glucose
in the blood,
Insulin
converts some
of it to
glycogen
Glucose in the blood
Diabetes
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Some people do not produce enough insulin.
When they eat food, the glucose levels in their
blood cannot be reduced.
This condition is known as Type 1 DIABETES.
Diabetics have to inject insulin into their blood,
continually monitor their blood glucose levels,
and be careful of their diet.
Diabetes can lead to other health conditions
including glaucoma & poor circulation.
Glucose
Concentration
Glucose levels rise
after a meal.
Insulin is produced
and glucose levels
fall to normal
again.
Normal
Meal eaten
Time
Glucose
Concentration
Glucose levels rise
after a meal.
Diabetic
Insulin is not
produced so
glucose levels stay
high
Meal eaten
Time
Negative Feedback:
Decrease in Blood Glucose Level
•After not eating for a while blood glucose
level decreases.
•Brain sends a message to the pancreas to
release glucagon ( a type of protein) into the
blood
•Glucagon stimulates the liver to convert
glycogen (stored energy) into glucose
•Glucose levels in the blood increases & the
body returns to homeostasis
Glycogen
If there is not
enough
glucose in the
blood,
Glucagon
converts some
glycogen into
glucose.
Glucose in the blood
Body Systems Involved in
Blood Glucose Regulation
• Endocrine system:
produces insulin and glucagon
(hormones/proteins)
•Circulatory System:
transports hormones (insulin &
glucagon), glucose & glycogen
to cells in the body.
•Nervous System: stimulates
a response by sending and
receiving messages to & from
cells….as a result glucose
levels increase or decrease.
Acids/
Bases/pH
Scale
pH Scale:
Indicates the
concentration
of H+ ions in
solution
pH levels
must be
maintained
Especially
for
digestion to
work
properly
Acids
 pH
of less than 7 (Example: HCl)
Bases
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pH of greater than 7 (Example: Bleach,
Ammonia
Buffers
Weak acids or bases that can react with strong acids or
bases to prevent sharp changes in pH.
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These are important for maintaining a constant internal
environment…..homeostasis (between 6.5 and 7.5 for
most cells)
Think of treatments used for stomach aches
For digestive enzymes to work properly, pH balance
must be maintained
To test for acid & bases: Litmus paper
base = blue
acid = red
Remember…Homeostasis in Plants
Negative Feedback Mechanism
Maintenance of Water
•plants need to regulate water loss and
carbon dioxide intake for
photosynthesis and other life activities
•when plants do not keep enough water
in their cells, they wilt and die
stomate: a microscopic hole in a plant leaf which allows gases
to enter and leave and water vapor to leave as well. Stomata is
the plural of stomate.
guard cells: open and close the stomate.
•the ability of the guard cell to close during periods of limited
water availability for the plant allows the plant to maintain
water homeostasis
Positive Feedback Mechanisms
Positive feedback is where the response is
the same as the stimulus.
In positive feedback the response can be
magnified.
Positive Feedback Mechanisms
A good example of positive feedback is the
feedback you hear from sound systems in
concerts.
In this example the stimulus (sound going into
microphone) is processed to produce a
magnified response (sound coming out of the
speakers).
Sometimes the microphone picks up sound from
the speakers and continues to magnify it until it is
out of control (the feedback that hurts your
ears).
Example in Humans:
Oxytocin & Child Labor
Positive Feedback in the Human Body
The release of oxytocin to intensify the
contractions that take place during childbirth
.[
In positive
feedback the
response
can be
magnified.
Name 2 systems that work
together.
Circulatory – respiratory
 Skeletal – muscular
 Digestive – circulatory
 Nervous – muscular
 Integumentary – circulatory
 Endocrine – circulatory
 Excretory - circulatory
How do they work together? ……. You will
investigate through your project & presentation!!
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