Transcript Document
31.2 Immune System
KEY CONCEPT
The immune system consists of organs, cells, and
molecules that fight infections.
31.2 Immune System
• The immune system is the body system that fights off
infection and pathogens.
31.2 Immune System
• Think of your body as a heavily guarded castle. When
pathogens invade they must break down the outer wall or
find a way around it. If the intruders get past the physical
barriers, they must face your body’s fighters in hand-tohand combat.
• Invaders are winning= you are sick
• Your body is winning= you are healthy
31.2 Immune System
What is our first line of defense?
• SKIN!!!!!!!
– Cuts and wounds are entry points
What are the other entry points?
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Eyes
Nose
Ears
Mouth
Excretory Organs (lungs)
31.2 Immune System
– Skin is a physical barrier to infection
- It is your first line of defense!
– Mucous membranes in these openings trap pathogens
entering the body.
– The circulatory system transports immune cells.
31.2 Immune System
SKIN
• First line of defense against pathogens
– Protection from infection
– Oil glands in skin
- Inhibit the growth of bacteria
31.2 Immune System
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Cut yourself
Bleed
Form blood clot
Blood clot dries out- Scab is formed
Skin cells divide and multiply- (mitosis)
Scab falls off
31.2 Immune System
Six main types of white blood cells
1) phagocyte- Destroys viruses, bacterium,
and fungi by engulfing them
Ex: macrophage
31.2 Immune System
2) T cells- Destroy body
cells that are infected
3) B cells- Produce proteins
that inactivate pathogens
that haven't infected body
cells yet
31.2 Immune System
4) Complement Proteins: made by white blood cells, and
weaken pathogen’s cell membrane allowing water in so it
will burst
31.2 Immune System
5) Antibodies: made by B cells
• Attack pathogens by “binding” themselves to the
pathogen to prevent them from attacking healthy cells
• Cause pathogen’s to clump, making it easier for
phagocytes to engulf and destroy
31.2 Immune System
6) Interferons: produced by body cells infected by a virus
• Stimulate uninfected body cells to produce enzymes that
will prevent viruses from entering and infecting them
• ***If a virus can’t enter it- it can’t reproduce!