Transcript Say No to Cancer!

SAY NO TO CANCER!
Welcome to Cancerland!!!!!!
BIGGEST MYTHS IN ORTHODOX MEDICINE
• Diet is not important – eat what you like
• Antioxidants interfere with treatment
• Vitamins and minerals can make cancer worse
• Oxygen causes cancer to spread
• Losing weight is inevitable
• If the doctor has no treatment to offer; that is it
• All complementary medicine is a waste of time, if it worked it would be mainstream
• Only a doctor can affect cancer, if they can achieve nothing you cannot influence the
situation and your body
INTEGRATIVE MEDICINE ABROAD
• Integrative Medicine Service at Memorial Sloan-Kettering Cancer Center.
• Worlds Oldest and Largest Private Cancer Centre founded in 1884
• Touch therapy, mind-body therapy, acupuncture, creative therapy, and nutrition
counselling, as well as exercise programs to improve strength and promote
relaxation.
• Their information resource provides evidence-based information about herbs,
botanicals, supplements, and more
EPIGENETICS
• Our genes are not fixed
• Different stimulus turns them on and turns them off
A gene can successfully alter its expression through a behaviour change or a
novel experience within minutes
The whole cascade of a gene becoming active or inactive starts with the signal
outside the cell not from material within it
We can modify our genetic history by turning on the genes we want and turning off the ones
we don’t want by working with the various factors in our environment
Some of those signals come from within the body such as feelings and thoughts
Others from the body's response to external environment such as pollution and sunlight
Stress is the biggest cause of epigenetic change
Epigenetics suggests that even though our DNA code never changes, thousands of
combinations, sequences and patterned variations in a single gene expression are possible.
This means that you not preprogramed biology holds the keys to your genetic destiny
So why not see your genes for what they really are –
 Providers of possibility
 Resources of unlimited potential
 A code system for personal commands
 Nothing short of transformational
DIET IS NOT IMPORTANT
Glucose fuels
cancer cells,
causes
inflammation
Cancer cells
thrive in acidic
inflammatory
environment
where normal
cells cannot
influence them
Inflammation
drives cancer
cells, interferes
with cell
communication
Inflammation - ‘I Ignite’
Increase the
risk of
cancer
Turn on
oncogenes
Bolster
resistance to
treatment
CANCER CELLS
• Glucose burning
• Glucose fermenting (require 20-30 times more glucose than glucose
burning cancer cells)
• Glucose fermenting cancer cells have lost ability to burn fats and oils
http://advancedsilversolution.files.wordpress.com/2008/05/coy-diet-patient-brochure.pdf
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What Came First?
Increased sugar uptake in cells is the result of the intense
metabolic demands of tumour cells and not a cause of
malignant transformation –or is it?
Glycosis
Mina Bissell, Berkeley Lab's Life Sciences Division
has shown that aerobic glycolysis -- glucose metabolism in the presence
of oxygen -- is not the consequence of the cancerous activity of malignant
cells but is itself a cancerous event.
A dramatic increase in sugar uptake could be a cause of oncogenesis
There are two new pathways through which increased uptake of glucose
could itself activate other oncogenic pathways.
Glucose transporter known as GLUT3, the concentrations of which
Onodera and Bissell showed are 400 times greater in malignant than in
non-malignant breast cells.
CLASSICAL KETOGENIC DIET
•
In the KD carbohydrates and, to a lesser extent, protein are restricted and replaced with fat.
•
The KD has been utilised for seizure control in children for over a century and is now being researched
for use in some cancers particularly brain cancer.
•
It is hypothesized that the diet may be beneficial for those with cancer sub-types related to obesity and
metabolic disease.
•
The classic KD implements a 4:1, 3:1 or 2:1 ratio of fats to protein and CHO, and requires strict
calculations and weighing of food with CHO in general ~20-30 g/d.
•
Side effects may be constipation, vomiting, lack of energy and hunger.
•
There are favourable changes in triglycerides and HDL cholesterol. LDL cholesterol may increase but
with increased LDL particle size.
It is estimated that malnutrition affects up to 80% of patients with
certain cancers, including cancer of the head and neck, gastrointestinal
tract cancer, and pancreatic cancer. Malnutrition is considered the cause
of 20–40% of all cancer-related deaths. All patients with cancer should
be considered at risk for inadequate calorie and nutrient intake
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GEO Prospective Cross-Sectional Multicentre Study Malnutrition
Among 313 patients enrolled in 11 centres
colorectal (58%), pancreatic (15%), gastric (11%), and hepatobiliary (10%) primary tumors
Prevalence of malnutrition was 52%. Moderate and severe malnutrition was present in 27%
and 25% of cases, respectively.
Doctors considered it in 36% and 6% of cases, respectively, thereby misclassifying 134
patients (43%). The agreement between the HAS definition and the physicians’ judgment
was very low (κ = 0.30).
Most of the patients who were identified as severely malnourished received no nutritional
support. Performance status and pancreatic and gastric cancers were independently
associated with malnutrition. Malnutrition levels are high, around 50%, unequally distributed
according to the primitive tumour. It is still underestimated by doctors.
Nutrition and Cancer
Volume 64, Issue 4, 2012
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CACHEXIA
• The causes of the increased or disproportionate energy expenditure are not
understood though several hypotheses exist for the associated hypermetabolic state
• Protein turnover might account for up to 50% of the REE with the liver
accounting for 20% to 25% of the overall oxygen consumption.
• Anabolic/catabolic balance becomes predominately catabolic
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PTS AND DEPRESSION
• 1/3 of patients suffer PTSD
• The physical and mental shock of having a life-threatening disease, of
receiving treatment for cancer, and living with repeated threats to one's body
and life are traumatic experiences for many cancer patients.
• 37 percent of the people reported that their PTSD symptoms have stayed or
even gotten worse after a 5-year period.
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© Cancer Options
SACN
FSA
Get Plenty
From Food
and the
Sun
Level
25mmols
400ius
daily
Experts Around
the World
Insufficient
From Food
6 Months None
From the Sun
Blood Level
125mmols
Min 2200ius
TWO BIGGEST CONTROVERSIES
1. Antioxidants
2.Probiotics
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EFFECTS OF CHEMOTHERAPY
Chemotherapy destroys tumour tissue as a result of
introducing powerful oxidation products, free radicals
and many orthodox oncologists are concerned that
antioxidants will reduce the efficacy of treatment.
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WHERE IT BEGAN
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Dr Keith Block and Robert Newman PhD then Professor of Cancer
Medicine at MD Anderson Medical Centre performed a systematic review
of clinical studies on the use of antioxidants during chemotherapy.
Results were published in peer reviewed journal Cancer Treatment
Reviews and the International Journal of Cancer
The findings demonstrated there is no scientific support for the blanket
ban on the use of antioxidants during chemotherapy. In fact the use of
antioxidants may confer significant benefit.
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Among The Findings
 All of the study data which included survival data showed similar
or better survival rates for the antioxidant group than for the
control group
 None of the trials supported the theory that antioxidants
diminished the effectiveness of the chemotherapy
 All but one of the studies showed better treatment response in
the antioxidant groups than in the control groups
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15 of 17 trials which assessed chemotherapy toxicities including diahorrea, weight
loss, nerve damage and low blood counts concluded that the antioxidant group
suffered similar or lower rates of these side effects than the control group.
Most importantly, when combining antioxidants with chemotherapy the existing
evidence strongly favours increased treatment tolerance with a reduction in side
effects.
It may avoid patients having to cut back on their chemotherapy dosing, interrupting
treatment schedules or abandoning treatment altogether.
A significant amount of evidence suggests the combination improves treatment
efficacy.
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CHEMOTHERAPY IMMUNE SUPPORT
Biobran
3 grams per day
Beta Glucans 2 grams
per day
Inositol
Hexaphosphate
Grapeseed Extract
800 mgs three times
per day on their own
100 mgs twice a day
Turmeric
Hair Loss
500 mgs three times
per day
Thymuskin
www.thymuskin.com
CHEMOTHERAPY DIAHORREA
Aloe Vera 50 mls
twice a day
Slippery Elm
370 mgs twice a
day
Probiotics
Lactobacillus As
detailed
Boswellia
800 mgs twice a
day
CHEMOTHERAPY DETOXIFICATION
Liver Support
Milk thistle 500 mgs day
Oxygen
Acetyl Cysteine 600 mgs
day
Infra Red Sauna
Baths bentonite clay,
Epsom salts
Breathing exercises
Fatigue
In advanced cancer patients receiving adjuvant therapies the prevalence of
cancer- associated fatigue is reported to be as high as 95%
Contributing Factors:
Anaemia
Decrease in
cellular energy
from mitochondria
Endocrine changes
Hypermetabolic
state (cells
competing for
nutrition)
Sleep Disturbances
Poor Nutrition
Low melatonin
Poor appetite
Anxiety
Release of
Inflammatory
cytokines
Insomnia
Depression
WHY TREATMENT CAUSES FATIGUE
• The free radicals ROS and RNS (Reactive nitrogen species) are naturally
occurring cellular oxidants that are usually present in low concentrations; they
are important cellular regulators and are involved in gene expression,
intracellular signalling, cell proliferation, antimicrobial defense and other
normal cellular processes
• However, when ROS/RNS are in excess over cellular antioxidants, oxidative
damage can occur to cellular structures
• Excess oxidative stress and activation of ROS/RNS pathways, which is in turn
linked to fatigue and fatiguing illnesses
Fatigue and Lipids
Cancer-associated fatigue and the chronic adverse effects of cancer therapy can be reduced
by Lipid Replacement Therapy (LRT) using membrane phospholipid mixtures given as food
supplements
: LRT significantly reduced fatigue in cancer patients as well as patients suffering from chronic
fatiguing illnesses and other medical conditions.
It also reduced the adverse effects of chemotherapy, resulting in improvements in incidence of
fatigue, nausea, diarrhoea, impaired taste, constipation, insomnia and other quality of life
indicators. In other diseases, such as chronic fatigue syndrome, fibromyalgia syndrome and
other chronic fatiguing illnesses
LRT reduced fatigue by 35.5-43.1% in different clinical trials and increased mitochondrial
function.
Functional Good in Health and Disease: 4:135-160
TREATMENT STRATEGIES
• Lipid replacement therapy reduces cellular oxidative damage
• Liver Support milk thistle 150 mgs per day
• Digestive enzymes to enhance absorption
• Check for candida in gut
• High GLA Studies have shown that gamma linolenic acid from borage oil is
helpful at preventing the weight loss, aim for 2 grams per day
• Co-enzyme Q10 to support cells ATP production
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Chemo Brain
Chemotherapy causes inflammation inflammatory cytokines cross the blood brain
barrier and affect the brain

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

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Also caused by hormone blocking drugs
Low blood counts
Infection
Anxiety
Insomnia
CHEMO BRAIN STRATEGY
LDN
5HTP
Vitamin
D3
Omega 3
Flax oil
Q10
Green tea
Ginkgo
L
carnitine
STRATEGY FOR RADIOTHERAPY
Selenium: helps limit the free radical damage from radiotherapy
following radiotherapy aids recovery. 200 aug per day.
Vitamin D3: is increasingly recommended by US and some UK improves
the success of the radiotherapy treatment programme. 5000ius per day.
Fish oils: have been shown to increase the differentiation of cancer cells
making them easier to treat with radiotherapy. Research has shown that
the intake of fish oils, linseed and hempseed rich in omega-3 fatty acids,
can increase the expression of the tumour suppressor gene, slowing
cancer growth
1000 mg twice a day.
Fatigue: Lipid Replacement Therapy, turmeric upon completion of full
effect of treatment
If to the brain Boswellia has much clinical evidence for reducing the
oedema associated with radiotherapy; 800 mgs twice a day
ANTI-INFLAMMATORY
• Boswellia 800 mgs per day
• Curcumin up to 3 grams per day
• Bromelain 400 mgs three times per day
• Short term use of steroids may be considered
• Low dose Naltrexone provides endorphin and appetite boost
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GUT
• Grape Seed Extract
• Studies show it significantly decreased intestinal damage compared to the chemotherapy
control;
• decreased chemotherapy-induced inflammation by up to 55%
• increased growth-inhibitory effects of chemotherapy on colon cancer cells in culture by 26%
• Our experimental studies have shown that grape seed extract reduced chemotherapy-induced
inflammation and damage and helped protect healthy cells in the gastrointestinal tract," says Dr
Cheah. "While this effect is very promising, we were initially concerned that grape seed could
reduce the effectiveness of the chemotherapy."
• "In contrast, we found that grape seed extract not only aided the ability of chemotherapy to kill
cancer cells, but was also more potent than the chemotherapy we tested at one concentration."
Fatigue
In advanced cancer patients receiving adjuvant therapies the prevalence of
cancer- associated fatigue is reported to be as high as 95%
Contributing Factors:
Decrease in
cellular energy
from mitochondria
Endocrine changes
Sleep Disturbances
Low melatonin
Anxiety
Insomnia
Depression
Anaemia
Hypermetabolic
state (cells
competing for
nutrition)
Poor Nutrition
Poor appetite
Release of
Inflammatory
cytokines
Oxygen
HYPERBARIC
• Hyperbaric Oxygenation causes down regulation of inflammatory cytokines
and the upregulation of Growth Factors required for stabilization and repair.
HBO suppresses stimulus-induced proinflammatory cytokine production
reducing the release of Tumour Necrosis Factor -alpha (TNF-a) and
Endothelins.
• HBO upregulates IL-10 - immune response anti-inflammatory which downregulates pro-inflammatory species IL-1β, IL-2, IL-6, tumour necrosis factor-α,
interferon-γ, matrix metalloproteinase-9, nitric oxide synthase,
myeloperoxidase, and reactive oxygen species
OXYGEN
The positive clinical effects of Hyperbaric Oxygenation in the
treatment of chronic inflammation is due to the effects on local
and systemic Inflammatory Cytokines - IL-1, IL-6, and Tumour
Necrosis Factor -alpha (TNF-alpha).
The effects of Hyperbaric Oxygenation on Prostaglandin,
Nitric Oxide, and Cytokines indicates that HBO has important
effects on the biology of cytokines and other mediators of
inflammation.
HBO improves Telomere function slowing degeneration.
CONTRIBUTORY VIRUSES
•
•
Seven types of viruses cause 10–15% of all human malignancies
•
Viral aetiology is particularly evident in cervical carcinoma (CESC), which is almost
exclusively caused by high-risk human papillomaviruses (HPV), and in hepatocellular
carcinoma (LIHC), where infection with hepatitis B virus (HBV) or hepatitis C virus
(HCV) is the predominant cause in some countries. In addition, several rare cancers
have a strong viral component, including Epstein–Barr virus (EBV)/human herpes virus
(HHV) in most Burkitt’s lymphomas.
•
They significantly effect the potential for recurrence is left untreated
Viruses can cause cellular transformation by expression of viral oncogenes, by
genomic integration to alter the activity of cellular proto-oncogenes or tumour
suppressors, and by inducing inflammation that promotes oncogenesis.
ANTI-VIRAL SUPPLEMENTS
• Goldenseal 2 grams per day
• Echinacea 250 mgs twice a day
• L-lysine 1 gram per day
• Andrographis 400 mgs twice a day
• Monolaurin 300 mgs twice a day
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VITAMIN C
• Evidence for support with chemotherapy for ovarian cancer
• As anti-inflammatory and pro-oxidant for most cancers
• Contra-indicated with ascites and pleural effusions (fluid in cavities)
• Study showed when used with chemo it:
Improves the Bcl2/Bac ratio
Lowers multi drug resistance
Shuts off the NF-kB mutation pathway
Anti-angiogenic properties
Causes differentiation of stem cells
Pro-apoptotic gene expression
• Dosage iv 75 grams 3 x week or liposomal 16 grams daily with lipoic acid
and vitamin K2
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Main Strategies to Consider
Nutrition
Exercise
Stress
Treatment
support
Detox
Love your
liver
Hormones
Reduce
inflammation
Oxygenate
WWW.CANCEROPTIONS.CO.UK
GC-MAF
• GcMAF (Gc protein macrophage activation factor) is an
immune-regulating treatment, Gc-maf activates the
scavenging cells of the immune system.
• Cancer cells produce nagalase, an enzyme that prevents
Vitamin D receptors (VDR) from being activated on the
surface of the macrophage .
• This prevents the body from making GcMAF by attacking
your GcProtein therefore macrophages are not activated.
• Using a ketogenic approach alongside it is encouraged
GcMAF (Gc protein macrophage activation
factor)
GcMaf is important part of our immune systems
Instructs macrophages to eat
cancer cells
Regulates Immunity
Cancer Destroys GC Maf by sending out protein Nalgalase
Prevents body from making GcMaf
Cancer cells go unchecked
Evidence
180 Scientists involved worldwide
80 Research papers
NALTREXONE
Binds to and inhibits
opiate receptors
Targets the opioid growth
factor (OGF)/opioid
growth factor receptor
(OGFr) pathway to inhibit
cell proliferation.
Prescribable subject to
worldwide campaign for
recognition and research
Regulates the growth of
cancer cells, and all cancer
cells use the OGF-OGFr
pathway in growth
regulation
Influences endorphins also
play a role in pain relief,
immune system regulation,
growth of cells and
angiogenesis
Low dosage safe and
enhances quality of life
Inflammation
Toxicity
Stress
Cancer
Hormones
Absorption
Immune
system
Treatment
Support
Normalise
body
systems
Repair the
immune
system
Recovery
Anti cancer
compounds
Alkalyse
Oxygen
Keep your
own
perspective
Become
an expert
on
yourself
Learn
what
heals you
“Good God!
They can’t still
be giving them
lots of that
chemotherapy”
BOLDLY GO INTO THE FUTURE
INTEGRATIVE MEDICINE