Transcript Jeopardy Abbas 1-3 (double) - updated 5/21/2014

Promoting
Maturity
Dec 2
Preview
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Generally KC, Here
speaking
I Come
Traffick
Jam
This promotes a
myeloid progenitor to
become a RBC
What is erythropoietin?
This promotes a myeloid
progenitor to become a
megakaryoblast.
What is thrombopoietin?
This interleukin
promotes a myeloid
progenitor to become a
eosinophil.
What is IL5?
This cytokine is
essential for mast cell
development.
What is stem cell factor
(or c-Kit ligand)?
This TNF family
cytokine is required for
naïve B cell survival.
What is BAFF
(or B cell activating
factor)?
It is the part of the
immune system that has
no memory.
What is the innate
immune system?
They are cells of the
innate immune system
that are sometimes
called
polymorphonuclear
cells.
What are neutrophils?
These small cationic
peptides are produced by
epithelial cells and are
directly toxic to microbes.
What are defensins
(or cathelicidins)?
These two cytokines are
known to downregulate
inflammation and induce
tolerance.
What are
IL-10 and TGF-β?
They are the largest group
of NK inhibitory receptors
and bind MHC class I
molecules.
What are KIRs?
This secondary
lymphoid organ is the
primary site of immune
response to blood borne
infections.
What is the spleen?
This cell transports
macromolecules from the
intestinal lumen into the
subepithelial tissue.
What is an M cell?
Along with CD62L, this
cell marker is found on
naïve T cells and is used
to diagnose complete
DiGeorge syndrome.
What is CD45RA?
Lymphocyte egress from
lymph nodes is dependent
on this concentration
gradient.
What is S1P/S1P1R?
This interleukin recruits
neutrophils, is secreted
by macrophages in
response to TLR
signaling and is a
mediator of psoriasis.
What is IL8?
This city hosted the most
NCAA men’s basketball
division I championships
th
in the 20 century
What is Kansas City?
Kansas City has more
fountains than any
other city in the world
except this city?
What is Rome?
The shopping area in
Kansas City known as
“the plaza” was modeled
after this city in Spain.
What is Seville?
The star of “Steamboat
Willie” was first drawn by
this cartoonist while he
was in an office on
Hospital Hill.
Who is Walt Disney?
Before receiving both a
Pulitzer Prize and a Nobel
Prize in Literature, this
man wrote for the Kansas
City Star.
Who is Ernest
Hemingway?
Both of these types of
selectins are found on
the endothelium.
What are E and P
selectins?
L-selectins are highly
expressed on naïve T
cells mediating their
binding to these on
HEVs.
What is peripheral
node addressin
(PNAd)?
MadCAM-1 binds to
this integrin on
lymphocytes during gut
homing.
What is α4β7?
This chemokine receptor
is found on naïve T cells
and helps them travel to
the T cell zone of lymph
nodes.
What is CCR7?
This chemokine receptor
is found on naïve B cells
and helps them travel to
lymph node follicles.
What is CXCR5?