Transcript What are free radicals? Why are they damaging to the human body?

What are free radicals? Why are
they damaging to the human
body? - by Newman Doo
Our body tissues are made up of
cells.
Each cell is composed of many
different types of molecules.
• Molecules consist of
one or more atoms of
one or more elements
joined by chemical
bonds.
An atom
• The number of protons
(positively charged
particles) in the atom
nucleus determines the
number of electrons
(negatively charged
particles) surrounding
the atom.
Electrons
Electrons surround, or
"orbit" an atom in one or
more shells.
How is Free Radical Formed?
• When a electron is lost
from an atom, an
unstable free radical is
formed.
Chain reaction of radical
formation.
When the molecule loses
its electron, it becomes a
free radical, beginning a
chain reaction. Once the
process is started, it can
cascade.
How a cell is damaged.
Finally a living cell is
disrupted.
Causes of free radical formationoxidative stress
Environmental factors
such as pollution,
radiation, cigarette
smoke and herbicides
also spawn free radicals.
Many drugs cause free radicals
• Drugs
adriamycin
bleomycin
mitomycin C
nitrofurantoin
chlorpromazine
Stress
The pressures common
in industrial societies can
trigger the body's stress
response. In turn, the
stress response creates
free radicals in
abundance.
Viruses and bacteria
• Sometimes the body
immune system
cells purposefully
create free radicals to
neutralize viruses and
bacteria.
Sports
Oxygen, although
essential to life, is the
source of the potentially
damaging free radicals.
Endurance exercise can
increase oxygen
utilization from 10 to 20
times over the resting
state.
Damages of free radicals
Free radicals may lead to
health problems such as
• skin aging
• heart disease
• cataracts
• cancer
• arthritis
• diabetes
Skin aging
Free radical damage
causes wrinkles by
breaking down skin
collagen, elastin and
other proteins in the skin.
Free radicals and heart disease
• Free radicals cause
damage to individual
cells within the
arteries.
Oxidized LDL(low density
lipoprotein)
LDL itself is harmless.
Only when oxidized-that is, does LDL
cause the arterial
hardening and clogging
that lay the groundwork
for heart attack and
stroke.
Free radicals and cancer
Free radicals damage
DNA causing tumor
initiation, promotion &
conversion .
Cataract
• A cataract is a
clouding of the lens in
the eye that affects
vision.
• Free radicals is a
major cause of cataract
formation.
Arthritis
Arthritis is believed to be a disease stemming from an attack of our
own T-Cells on our joint membranes and fluids. The T-cells make
deadly free radicals to use in attacking enemies like bacteria, viruses,
and cancer cells. But when the T-cells make mistakes and attack our
own cells, they use the damaging free radicals on us. In arthritis, the
chemically reactive free radicals damage the joint membranes and
lubricants, resulting in the pain and limited mobility of arthritis.
Diabetes
Free radicals damage
insulin-producing “beta
cells” in the pancreas
causing diabetes.
How Antioxidants May Prevent
Against Free Radical Damage
An antioxidant can neutralize a free radical by
donating one of its electrons without
jeopardizing its own chemical stability.
It is a free radical scavenger and
prevents cell damage.
An electron circuit to prevent oxidation of cell membrane by
antioxidants OPC, Vitamin C & E.
Isotonix OPC-3
• Red wine extract, pine
bark, isoflavonoids,
bilberry and grape seed
extract are the strongest
known antioxidants.
• 20 – 50 times more
effective than vitamin C
and vitamin E
respectively, at
neutralizing oxygen
radicals
•Improves skin smoothness & elasticity
•Strengthens capillaries, arteries and veins
•Improves circulation and enhances cell vitality
•Reduces capillary fragility and improves resistance
to bruising and strokes
•Reduces the risks of phlebitis(a clot in the vein)
•Reduces edema and selling in the legs
•Reduces varicose veins
•Reduces restless legs syndrome
•Improves visual acuity
•Helps improve sluggish memory
•Reduces the effects of stress
•Improves joint flexibility and reduces inflammation
caused by arthritis and sports injuries
Administration of OPC-3 Dosage
• Take on an empty stomach and wait 10-15 minutes before
eating or drinking.
• Loading dose – For the 1st 7 days, take 1 white capful per
every 75 pounds of body weight. OPC-3 is non-toxic.
• Those with physical challenges, continue the loading dose
for up to 30 days before shifting to a maintenance dose.
• For preventative health measures, a maintenance dose is
considered to be 1-2 capfuls of OPC-3.
• I white capful contains 75 mg of active OPC and 50 mg of
bioflavonoids.
Isotonix OPC-3 the best
deliverable system for absorption