Transcript Genital Herpes

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Genital Herpes
By: Katie Redinger
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History
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Known for at least 2,000 years
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Emperor Tiberious banned kissing due to cold sores
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History
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“Vocational disease of women”
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Not found to be a virus until the 1940s
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History
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Disease became stigmatized during the 1970s
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Merely a cold sore in an odd place
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What is Genital Herpes?
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STD caused by Herpes Simplex Virus – Type 1 or 2
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Most caused by HSV-2
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What is Genital Herpes?
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Herpesviridae family
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Similar to Hand, Foot and Mouth disease
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What is Genital Herpes?
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Lays dormant in ganglion
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Never goes away
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Flare ups occur in location of exposure
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What is Genital Herpes?
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Infection at one site prevents infections starting in another
site. (Genital, Oral, Ocular, Whitlow)
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Creates antibodies
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Structure
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Double stranded DNA virus
Uses RNA polymerase II to create viral DNA
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Symptoms
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Break outs of blisters, chancres, and tender ulcers
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More serious cases affect the eye and central nervous system
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Symptoms
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First outbreak usually occurs within 2 weeks of exposure
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May also include flu-like symptoms
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Frequency decreases overtime (4-5 within a year)
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Complications
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Bell’s Palsy, facial paralysis, may be caused by HSV-1
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Proposed Alzheimer's.
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Transmission
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Contact with ruptured sores
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Skin to skin contact
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Sexual contact
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Transmission
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Can occur between outbreaks
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Skin may contain virus without sores (small rash)
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Transmission
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HSV-2 Genital to Genital
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HSV-1 Oral to Oral, Hand to Oral, Oral to Genital
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Demographics
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16.2 % (1/6) Americans ages 14-49 have HSV-2
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More common in women
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Transmission is more common Male  Female (8-10%)
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Demographics
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Worldwide rate of infection 60-90%
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Prevention
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Use of condoms
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Abstinence
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Living with Herpes
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Topical creams
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Vaccines are in clinical trial
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Antivirals
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Sources