Transcript Changes of Presenile Cataracts that had been Operated over

Changes of Presenile Cataracts
that had been Operated over 10 years
in Korea
Sung Kun Chung, M.D. ; Eun-Jung Jun, M.D.
Hyun Seung Kim.
Department of Ophthalmology and Visual Science,
The Catholic University of Korea
No author has any financial or proprietary interest in
any materials or methods mentioned
Introduction
Many studies about senile cataract
: aged more than 60 years old
: age is one of the most important risk factors of cataract


Presenile cataract patients may display different
characteristics from senile cataract patients
Purpose

To investigate the long-term characteristics and
changes of presenile cataracts that had been
operated in Korea.
Materials & Methods

①
②

①
②
Inclusion criteria
aged from 30 to 50 years
underwent cataract surgeries
at St. Mary’s hospital
from 1995 to 2004(n=976)
Exclusion criteria
patients with histories of ocular trauma
or uveitis
those received combined surgeries


①
②
③
④
Retrospective review of medical
records
Analyze
age & sex : 31-40, 41-50 group
their histories of diabetes and
hypertension
types of lens opacities
preoperative and postoperative
visual acuities
•Lens opacity grading : LOCSⅢ
(Lens Opacity Classification System III)
• Statistical analysis
: Cochran-Armitage proportion trend test
Results
30-39 years
40-49years
Total
Mean age
36.2
45.3
41.7
Male
299(38.8%)
472(61.2%)
771(79.0%)
Female
81(39.5%)
124(60.5%)
205(21.0%)
History of diabetes
20(20.0)
78(80.0)
98(10.0%)
History of hypertension
16(21.1%)
60(78.9%)
76(7.8%)
Results
Results
Lens opacities in each age group (LOCSⅢ)
Anterior
polar
Opacity
Posterior
subcapsular
opacity
(PSCO)
Anterior
polar
opacity
+PSCO
Cortical
opacity
Nuclear
opacity
30-39years
n
(%)
147
(42.2%)
104
(30.3%)
34
(50%)
12
(20.3%)
16
(30.2%)
40-49years
n
(%)
201
(57.8%)
239
(69.7%)
34
(50%)
47
(79.7%)
37
(69.8%)
Total
n
(%)
348
(35.7%)
343
(35.1%)
68
(7.0%)
59
(6.0%)
53
(5.4%)
Results
Region
of study
Sample
ze, race
Beijing,
China
Shih-Pai
,Taiwan
Singapo
re
4439,
Chinese
1361,
Chinese
1717,
Chinese
919,
Sumatra,
Indonesia
si Methods
of evaluation
Indonesian
Victoria,
Australia
4433,
Korea
976,
Korean
Australian
Age
Prevalence(%)
Group Cortical
Nuclear
(yrs)
PSC
Male
slit-lamp
c AREDS
Slit-lamp
c LOCSⅢ
Slit-lamp
c LOCSⅢ
Slit-lamp
c LOCSⅢ
≥ 40
0.3
82.2
4.3
≥ 65
21.9
38.9
9.2
40-79 23.9
22.6
7.0
≥ 21
4
5.7
No statistically significant
difference in gender
Female
predominance
No statistically significant
difference in gender
Female
predominance
except cortical cat.
Slit-lamp
c WCGS
Slit-lamp
c LOCSⅢ
≥ 40
11.3
12.6
4.08
5.4
35.1
30-49 6.0
*PSC : posterior subcapsular
*c : with
*AREDS : Age-related Eye disease Study
*LOCSⅢ : Lens Opacities Classification System Ⅲ
*cat. : cataract
*JCCESG : Japanese Cooperative Cataract Epidemiology Study Group
*WCGS : Wilmer cataract grading scheme
Prevalence(%)
Female
Female
predominance
Male
predominance
Results

Eyes that had surgeries for presenile cataracts displayed
statistically significant decrease(p = 0.0002, CI 95%)

Presenile cataracts with diabetes showed no significant trend
with the passage of time(p = 0.4767, CI 95%)

Presenile cataracts with hypertension showed statistically
significant increase (p = 0.0049, CI 95%)
Conclusion

Presenile cataract patients had different characteristics from
senile cataract patients.

Men consisted of the majority of the presenile cataract
patients.

Anterior polar opacity was the most common type of lens
opacity.

Cataracts with hypertension showed overall increase over 10
years.