Transcript Slide 1

Visual Outcomes After Temporary
Keratoprosthesis
Kristin C. Bains, MD
Robert Phillips, MD
The authors have no financial interest in the subject matter of this
poster
Purpose
• To evaluate visual outcomes
after combined penetrating
keratoplasty (PK) and
vitreoretinal surgery using
temporary keratoprosthesis
(TKP)
Introduction
• Utilized in patients with coexisting corneal and
vitreoretinal pathology
• Combined procedure necessary for adequate
visualization intraoperatively
• If combined only with PK, delay waiting for graft to
clear, leading to worsening retinal pathology
• Does not expose patient to risks associated with
open-sky vitrectomy
• Attempts to restore visual function by allowing
earlier surgical intervention
Methods
• IRB approval obtained
• Retrospective, observational case series
– CPT code 65770
– Date range: 2003-2010
– 55 eyes of 47 patients identified
• 1 corneal surgeon, multiple vitreoretinal surgeons
• Included: 47 eyes of 41 patients who underwent
combined TKP/PK and vitreoretinal surgery
• Excluded: 8 eyes of 6 patients lost to follow-up
• Previous surgeries common
Baseline Characteristics
Age (years)
<31
31-60
>61
N=20
N=14
N=13
Gender
Male
Female
N=31
N=16
Eye
OD
OS
N=24
N=23
Visual acuity
Ambulatory
HM
LP
NLP
N=11
N=11
N=25
N=0
Baseline Characteristics (cont.)
Cornea status
Scar
Rejected graft
BK
N=23
N=19
N=5
Retina status
RD
Attached
Macular pucker
Choroidal hemorrhage
Vitritis
Macular hole
N=29
N=12
N=3
N=1
N=1
N=1
Comorbid ocular disease
Secondary glaucoma
Amblyopia
Bells’ palsy
Traumatic optic
neuropathy
Traumatic maculopathy
N=11
N=3
N=1
N=2
N=1
Baseline Characteristics
Reasons for TKP/PK
Atraumatic
Traumatic
Traumatic
injury
Yes
No
N=37
N=10
Methods
• Wide-field Landers TKP
• Vitreoretinal procedures
– 3 port ppv
– Pars plana lensectomy if
indicated
– Retinal reattachment
• Penetrating keratoplasty
Results
• Follow-up: 1 month- 67 months
• Mean pt follow-up: 23.4 months
• Post-operative graft status at final follow-up
•
17 clear (36.9%)
•
29 rejected
•
7 repeat TKP/PK
•
5 repeat PK
Results
Pre- and Post-TKP/PK Visual Acuities
30
Number of Patients
25
20
15
10
5
0
Ambulatory
Hand Motion
Light Perception
NLP
Pre-op
11
11
25
0
Post Op
16
17
6
8
Conclusions
• Before combined surgery 21 eyes had
BCVA of ambulatory to HM.
• Post-operatively, majority of patients
(32 eyes) had BCVA of ambulatory to
HM.
• 93.6% of eyes (44 eyes) were retained
• 2.1% of eyes (1 eye) became phthisical
Conclusion
• Tool used in management of complex
disease, without which, many eyes
could not be salvaged
• Combined surgery is not without
complications
• Outcomes can be good considering
complexity of pathology