Transcript Slide 1

Introduction to the
Neuromonics Tinnitus Treatment
For Candidates
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Neuromonics Background
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Core technology conceived in 1993
Neuromonics formed in 2001
Current locations; Bethlehem, PA & Sydney, Australia
Randomized clinical trials with >200 tinnitus patients
Thousands of patients treated worldwide
FDA clearance 2005
Regulatory approval in: United States, Australia, New
Zealand and Singapore
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Tinnitus Population
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50 Million suffer from tinnitus
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10-15 Million seek medical treatment for tinnitus
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2 Million have severe, highly disturbing tinnitus
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1 Million new cases of tinnitus are identified per year
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400,000 Veterans on tinnitus disability
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Pathogenesis of Tinnitus
Auditory
Perception
Attention and
Awareness
Emotional
Response
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Sub-Cortical Awareness Processing
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Neuromonics: Mechanism of Action
Auditory
Attentional
Emotional
1. Perception
2. Attention
3. Reaction
Stimulation
Desensitization
Relaxation & Relief
Acoustic signal
Helps retrain the
brain to be less
customized for each
patient’s hearing profile aware and bothered
by tinnitus in relaxed
(stereo)
state
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Hanley PJ, Davis PB. Treatment of tinnitus with a customized, dynamic acoustic neural
stimulus: underlying principles and clinical efficacy. Trends in Amplification. 2008;
Sep;12(3):210-22. Epub 2008 Jul 9.
Pleasant, relaxing
music.
Relief from tinnitus
perception.
What is Neuromonics Tinnitus Treatment?
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Non-invasive, FDA cleared, patented and clinically
tested
Proven long-term reduction of tinnitus disturbance
Clinically administered and monitored by a trained
clinician
Combines a novel approach to acoustic stimulation with
structured counseling and support
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Neuromonics Tinnitus Treatment
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Treatment signal and music is customized to your
hearing profile
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Decreases awareness and disturbance to the tinnitus
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Treatment duration is generally 6 - 8 months but can
vary depending on your individual case
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Treatment Usage
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Required usage is 2 - 4 hours per day when the tinnitus
is most bothersome
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Can use in small segments of time during the day
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For example: 15, 30 or 60 minute time intervals
Device tracks usage throughout the day
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Treatment Usage
Treatment cannot be used when:
 Driving
 Straining to hear
 Listening to television
 Device may get wet
 Exercising to raise your heart rate
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Appointment Schedule
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Fitting of your customized device
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Periodic follow-ups to monitor progress approximately
every 8 to 10 weeks
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Retest measurements as needed
Download logged data from device
Final appointment
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Treatment Stimulus
Treatment signal is a customized stimulus which is
embedded in music
 Music mimics the resting heart rate to help with
relaxation
 Specially chosen for its frequency response to
maximize stimulation of the auditory pathways
 Styles of music used
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Classical Baroque Style
Contemporary/Relaxation Style
Importance of Customization
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0
2
0.25
0.5
3
4
1
2
Pitch
kHz
6
7
4
6
8
8
10
9
12
Music
10
20
30
40
dB
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Maximize stimulation of
the auditory pathways
Stereo effect- balances
right and left ear
Allows for more relief
from tinnitus at a lower
listening volume
Able to use treatment for
sleep
Helps with relaxation
Loudness
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1
50
60
Thresholds
70
80
90
100
110
Spectral Composition of Music +
Hearing Thresholds of Typical
Clinic Patient Sample
Device
 Easy to use
 Volume control allows you to set at a comfortable level
 Monitors daily and cumulative usage
 Rechargeable battery
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Treatment: Stage 1
(Schematic)
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The first stage is designed to
help you get relief from the
tinnitus while using the
treatment and also to help you
relax
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High level of interaction
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Relief and reduction of tinnitus
awareness during listening
sessions
Treatment: Stage 2
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The purpose of the second stage of
treatment is to help re-train your
brain to be less aware and less
bothered by the tinnitus
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Intermittent interaction with
tinnitus
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See results even when not using
the treatment
Intensity
(Schematic)
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Clinical Outcomes (after 6 months of treatment*):
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40% + Reduction in Tinnitus Disturbance**…… 95%
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40% + Reduction in Tinnitus Awareness………… 84%
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5 dB + Reduction in MML***..……………………… 78%
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5 dB + Improvement in LDL****..………………… 69%
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Davis, P, Paki, B, Hanley, P. Neuromonics Tinnitus Treatment: Third Clinical Trial.
Ear and Hearing. 2007; Vol. 28, No. 2; 242-257.
*Clinical measures reported by participants with significant
levels of tinnitus disturbance prior to treatment.
**Measured by the Tinnitus Reaction Questionnaire
***Participants with pretreatment minimum masking level of greater than 5dB
****Participants with decreased sound tolerance
Patient Satisfaction
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Relief from tinnitus …………………………. 97%
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Improved ability to fall asleep ………… 94%
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A sense of control of tinnitus …………. 94%
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Improved ability to relax …………………. 94%
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Davis, P, Paki, B, Hanley, P. Neuromonics Tinnitus Treatment:
Third Clinical Trial. Ear and Hearing. 2007; Vol. 28, No. 2; 242-257.
www.neuromonics.com
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