Transcript Gene Response to Photoperiod Changes in the Atlantic salmon

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Marlene Lorgen1, Elisa Casadei1, David Hazlerigg1 and Sam Martin1
1School of Biological Sciences, University of Aberdeen
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Atlantic Salmon Life Cycle
EGG
Fresh Water
ALEVIN
Parr-Smolt Transformation (PST)
FRY
Critical transformation from freshwater juvenile
(PARR) to sea water adapted juvenile (SMOLT)
Controlled by active thyroid hormone (T3)
T3 availability determined by action of
deiodinases (Dios)
SPAWNING
Dios
regulated by photoperiod in birds and
ADULTS
mammals
Increased Dio2 causes increase in T3
RETURNING ADULT
Salt Water
PARR
SMOLT
Dio Response to External Environment
S. salar Dio GeneGill
Identification:
Fresh
Salt
Photoperiod, h
Photoperiod, h
Brain
Partial
Dio
Sequences
Cloned
TheSTAY
Next
TUNED!
Question:
Dio2a How do these 2 very
NO CHANGE
similar
Thanks
genes
forrespond
your
BLAST
S. salar
Genome
Show Response
to External
Environment
to different
Attention
signals?
Dio1
SALMONID
Ancestral
Dio2
2
Dio2a
Dio2a
Dio2b
Dio2b
Dio3a1 Salinity Responsive
Dio3a2 DIFFERENTIAL
FUNCTIONALIZATION
Dio3b Photoperiod Responsive
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