Growth hormone-releasing hormone
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Transcript Growth hormone-releasing hormone
HORMONES
It is a chemical
substance which is
produced in one part of
the body, enters the
circulation and is
carried to distant target
organs and tissues to
modify their structures
and functions.
brain
(hypothalamus)
pituitary (pituitary
level)
endocrine organs
(body-level)
tissues
brain
(hypothalamus)
Thyrotropin-releasing hormone (TRH)
Corticotropin-releasing hormone (CRH)
Gonadotropin-releasing hormone (GnRH)
Growth
hormone-releasing
hormone (GHRH)
pituitary
(pituitary
level)
endocrine organs
(body-level)
tissues
FSH – Follicle-stimulating hormone
LH – luteinizing hormone
ACTH – Adrenocorticotropic hormone
TSH – Thyroid-stimulating hormone
GH – growth hormone
PRL -- prolactin
OT -- oxytocin
ADH – antidiuretic hormone
FSH – Follicle-stimulating hormone
LH – luteinizing hormone
ACTH – Adrenocorticotropic hormone
TSH – Thyroid-stimulating hormone
GH – growth hormone
PRL – prolactin
OT -- oxytocin
ADH – antidiuretic hormone
TROPIC hormones
(they activate some
other endocrine gland)
have effect on other body
tissues (not directly on
other endocrine glands
from the posterior
pituitary
brain
(hypothalamus)
pituitary (pituitary
level)
endocrine organs
(body-level)
tissues
Thyroid Function
two very different parts of the adrenal gland
adrenal cortex (outside)
secretes cortisol, aldosterone, other hormones
adrenal medulla (inside)
connected directly to nerve fibers from the hypothalamus
secretes adrenalin and noradrenalin
exophthalmia
protruding eyes
hypersecretion of thyroxine
increased pressure on eyes
note neck scar from thyroidectomy
Hypothyroidism
•aka myxedema
•if low thyroxin in adult
•low BMR
•lethargy
•dry brittle hair
•impaired memory
•thick tongue
•slow speech
•voice deep and coarese
•diminshished perspiration
•reddened cheeks
•megaloglossia
•increased pigment elbows/knees
usually....
•thyroid makes thyroxine
•when thyroxine level too low,
body signals thyroid gland to
make more
but with goiter
•thyroid can’t make thyroxine for
some reason
•but body is still telling thyroid to
make more
•therefore thyroid enlarges
cretinism
•lack of thyroxine
from birth
•or before birth
•could be from lack
of thyroid gland
•or lack of iodine in
mother
•severe and
irreparable mental
defects
•stunted growth
•reduced growth and
function of many
organs
List of Endocrine disorders
Acromegaly
Addison's Disease
Adrenal Cancer
Adrenal Disorders
Anaplastic Thyroid Cancer
Cushing's Syndrome
De Quervain's Thyroiditis
Diabetes
Follicular Thyroid Cancer
Gestational Diabetes
Goiters
Graves' Disease
Growth Disorders
Growth Hormone Deficiency
Hashimoto's Thyroiditis
Hurthle Cell Thyroid Cancer
Hyperglycemia
Hyperparathyroidism
Hyperthyroidism
Hypoglycemia
Hypoparathyroidism
Hypothyroidism
Low Testosterone
Medullary Thyroid Cancer
MEN 1
MEN 2A
MEN 2B
Menopause
Metabolic Syndrome
Obesity
Osteoporosis
Papillary Thyroid Cancer
Parathyroid Diseases
Pheochromocytoma
Pituitary Disorders
Pituitary Tumors
Polycystic Ovary
Syndrome
Prediabetes
Reproduction
Silent Thyroiditis
Thyroid Cancer
Thyroid Diseases
Thyroid Nodules
Thyroiditis
Turner Syndrome
Type 1 Diabetes
Type 2 Diabetes
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