Transcript Slide 1

Endocrine System
Figure 26.2A_s1
Water-soluble
hormone
1
Target cell
Nucleus
Interstitial fluid
Receptor
protein
Plasma
membrane
Figure 26.2A_s2
Water-soluble
hormone
1
Interstitial fluid
Receptor
protein
Plasma
membrane
Target cell
2
Signal
transduction
pathway
Relay
molecules
Nucleus
Figure 26.2A_s3
Interstitial fluid
Water-soluble
hormone
Receptor
protein
1
Plasma
membrane
Target cell
2
Signal
transduction
pathway
Relay
molecules
3
Cytoplasmic
response
Cellular responses
or
Gene regulation
Nucleus
Figure 26.2B_s1
Interstitial fluid
Steroid
hormone
1
Target cell
Nucleus
Figure 26.2B_s2
Interstitial fluid
Steroid
hormone
1
Target cell
2
Receptor
protein
Nucleus
Figure 26.2B_s3
Interstitial fluid
Steroid
hormone
1
Target cell
2
Receptor
protein
Nucleus
DNA
3
Hormonereceptor
complex
Figure 26.2B_s4
Interstitial fluid
Steroid
hormone
1
Target cell
2
Receptor
protein
Nucleus
3
Hormonereceptor
complex
DNA
4
Transcription
mRNA
New
protein
Cellular response:
activation of a gene and synthesis
of new protein
Figure 26.4A
Brain
Hypothalamus
Posterior pituitary
Anterior pituitary
Bone
Hypothalamus: the master gland
Figure 18–9 Pituitary Hormones and Their Targets.
Copyright © 2009 Pearson
Education, Inc., publishing as
Pearson Benjamin Cummings
Figure 26.4B
Hypothalamus
Neurosecretory
cell
Hormone
Posterior
pituitary
Blood
vessel
Oxytocin
Uterine muscles
Mammary glands
Anterior
pituitary
ADH
Kidney
tubules
Figure 26.4C
Neurosecretory
cell of hypothalamus
Blood
vessel
Releasing hormones
from hypothalamus
Endocrine cells of
the anterior pituitary
Pituitary hormones
TSH
ACTH
FSH
and
LH
Thyroid
Adrenal
cortex
Testes or
ovaries
Prolactin
(PRL)
Growth
hormone
(GH)
Entire
Mammary
glands
body
(in mammals)
Endorphins
Pain
receptors
in the brain
Figure 26.4E
Hypothalamus
Inhibition
TRH
Anterior
pituitary
TSH
Thyroid
Thyroxine
Inhibition
The Thyroid Gland
Figure 18–10a The Thyroid Gland.
Copyright © 2009 Pearson
Education, Inc., publishing as
Pearson Benjamin Cummings
Figure 26.9
Adrenal
gland
Kidney
Adrenal
medulla
Adrenal
cortex
Stress
Nerve
signals
1
Hypothalamus
3
Releasing hormone
Cross section of
spinal cord
Anterior pituitary
Nerve cell
4
Nerve cell
Blood vessel
ACTH
5
Adrenal medulla
ACTH
Adrenal
cortex
2
Epinephrine and
norepinephrine
Short-term stress response
1. Glycogen broken down to glucose;
increased blood glucose
2. Increased blood pressure
3. Increased breathing rate
4. Increased metabolic rate
5. Change in blood flow patterns,
leading to increased alertness and
decreased digestive and kidney activity
Mineralocorticoids
Glucocorticoids
Long-term stress response
Mineralocorticoids
Glucocorticoids
1. Retention of sodium
ions and water by
kidneys
2. Increased blood
volume and blood
pressure
1. Proteins and fats
broken down and
converted to glucose,
leading to increased
blood glucose
2. Immune system may
be suppressed