Transcript Chapter 1

Chapter 1
An Introduction to the Human Body
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Anatomy
science of structure
 relationships revealed by dissection (cutting apart)
 imaging techniques
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Physiology
science of body functions
 normal adult physiology studied in this text
 some genetic variations described
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Subdivisions of A & P = Table 1.1
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Clinical Observational Techniques
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Palpation
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feel body surface with hands
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Auscultation
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listen to body sounds with stethoscope
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pulses and breathing rates
abnormal fluid in lungs
Percussion
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tap on body surface and listen to echo
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air in intestines
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Levels of Organization
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Chemical
Cellular
Tissue
Organs
System Level
Organismic Level
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Levels of Structural Organization
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Chemical Level
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Cellular level
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atomic and molecular level
smallest living unit of the body
Tissue level
group of cells and the materials surrounding them
that work together on one task
 4 basic tissue types
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epithelium, muscle, connective tissue, and nerve
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Levels of Structural Organization
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Organ level
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grouping of 2 or more tissue types into a recognizable
structure with a specific function.
Organ system
collection of related organs with a common function
 sometimes an organ is part of more than one system
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Organismic level
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one living individual.
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Interaction of Organ Systems
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All major body systems will be examined
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Interaction of different systems of the body
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skin produces vitamin D needed for calcium
absorption and bone growth
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bone marrow produces cells which help the skin resist
infection.
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Life Processes
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Metabolism = sum of all chemical processes
breakdown of large molecules into small
 building new structural components (proteins)
 providing chemical energy for cells
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Responsiveness
detect & respond to changes in internal or external
environment
 some typical responses
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muscle contraction, electrical signals, hormone or glandular
secretion
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Life Processes
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Movement at any structural level
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Growth
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the body, an organ, a cell or cell component
increase in number or size of cells or the material
found between cells
Differentiation
specialization of cells for a specific function
 stem cells give rise to cells that specialize
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Reproduction
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formation of new cells or new individuals
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Autopsy
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Postmortem examination of body by dissection
Purpose
confirm or determine cause of death
 support findings of other tests
 provide information on effects of drug usage
 educate healthcare students
 reveal congenital defects
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Homeostatis
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Maintaining the internal environment within
physiological limits
First described by French physiologist, 1813-1878
Process named by Walter Cannon, 1871-1945
Example
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blood glucose level is kept within narrow range 70110/100ml
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Homeostasis of Body Fluids
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Delineation of fluid compartments
intracellular fluid (ICF) = within cells
 extracellular fluid (ECF) = outside cells
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intercellular fluid = tissue fluid = interstitial fluid
plasma = fluid portion of blood
Composition of fluids change as substances move
between compartments
 nutrients, oxygen, ions and wastes move in both
directions across capillary walls
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Control of Homeostasis
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Homeostasis is continually being disrupted by
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external stimuli or
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intense heat, cold , and lack of oxygen
internal stimuli
psychological stresses
 exercise
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Disruptions are usually mild & temporary
If homeostasis is not maintained, death may
result
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Neural and Endocrine Controls
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Process of maintaining a controlled condition
sensory receptors detect change in a monitored variable
 nervous system and/or endocrine system responds
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Example of control of blood gas level
exercise increases blood CO2 levels
 sensory receptors detect change
 nervous system increases heart and breathing rates to
remove excess CO2
 adrenal gland releases epinephrine to increase heart and
breathing rates
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Components of Feedback Loop
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Receptor
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Control center
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monitors a controlled condition
determines next action
Effector
receives directions from the
control center
 produces a response that
changes the controlled condition
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Negative & Positive Feedback Loops
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Negative feedback loop
original stimulus reversed
 most feedback systems in the body are negative
 used for conditions that need frequent adjustment
 body temperature, blood sugar levels, blood pressure
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Positive feedback loop
original stimulus intensified
 seen during normal childbirth
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Homeostasis of Blood Pressure
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Pressure receptors in walls of
certain arteries detect an increase
in BP
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blood Pressure = force of blood
on walls of vessels
Brain receives input and signals
heart and blood vessels
Heart rate slows and arterioles
dilate (increase in diameter)
BP returns to normal
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Positive Feedback during Childbirth
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Stretch receptors in walls of
uterus send signals to the brain
Brain releases hormone
(oxytocin) into bloodstream
Uterine smooth muscle
contracts more forcefully
More stretch, more hormone,
more contraction etc.
Cycle ends with birth of the
baby & decrease in stretch
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Homeostatic Imbalances
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Disorder = abnormality of function
Disease = homeostatic imbalance with distinct
symptoms---changes in body function felt by the patient
such as nausea and
 signs----changes in body function that can be observed
by the doctor such as rash or fever
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Diagnosis---skill of distinguishing one disease from
another
Epidemiology----how disease is transmitted
Pharmacology --- how drugs used to treat disease
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Basic Anatomical Terminology
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Anatomical position
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Regions of the body
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Anatomical planes, sections and directional
terms
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Anatomical Position
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Standardized position from which to
describe directional terms
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standing upright
facing the observer, head level
eyes facing forward
feet flat on the floor
arms at the sides
palms turned forward
Prone position = lying face down
Supine position = lying face up
anatomical position?
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Common Regional Names
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Clinical terminology based on a Greek or Latin root word.
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Planes and Sections
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A plane is an imaginary
flat surface that passes
through the body.
A section is one of the 2
surfaces (pieces) that
results when the body is
cut by a plane passing
through it.
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Sagittal Plane
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Sagittal plane
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Midsagittal plane
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divides the body or an
organ into left and right
sides
produces equal halves
Parasagittal plane
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produces unequal
halves
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Other Planes and Sections
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Frontal or coronal plane
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Transverse(cross-sectional) or
horizontal plane
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divides the body or an organ into
front (anterior) and back
(posterior) portions
divides the body or an organ into
upper (superior) or lower (inferior)
portions
Oblique plane
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some combination of 2 other
planes
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Planes and Sections of the Brain
(3-D anatomical relationships revealed)
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Horizontal Plane
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Frontal Plane
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Midsagittal Plane
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Major Directional Terms
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See Definitions page 14
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Superior or Inferior
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Superior
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towards the head
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The eyes are superior
to the mouth.
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Inferior
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away from the head
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The stomach is
inferior to the heart.
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Dorsal or Ventral
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Dorsal or Posterior
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at the back of the body
The brain is posterior to
the forehead.
Ventral or Anterior
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at the front of the body
The sternum is anterior to
the heart.
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Medial or Lateral
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Medial
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nearer to the midline of
the body
The heart lies medial to
the lungs.
Lateral
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farther from the midline
of the body
The thumb is on the
lateral side of the hand.
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Proximal or Distal
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Proximal
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nearer to the attachment of the
limb to the trunk
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The knee is proximal to the
ankle.
Distal
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farther from the attachment of
the limb to the trunk
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The wrist is distal to the elbow.
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Dorsal Body Cavity
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Near dorsal surface of
body
2 subdivisions
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cranial cavity
holds the brain
 formed by skull
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vertebral or spinal canal
contains the spinal cord
 formed by vertebral
column
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Meninges line dorsal
body cavity
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Ventral Body Cavity
Near ventral surface of
body
2 subdivisions
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thoracic cavity above
diaphragm
abdominopelvic cavity
below diaphragm
Diaphragm = large,
dome-shaped muscle
Organs called viscera
Organs covered with
serous membrane
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Abdominopelvic Cavity
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Inferior portion of ventral body cavity below diaphragm
Encircled by abdominal wall, bones & muscles of pelvis
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Thoracic Cavity
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Encircled by ribs, sternum, vertebral column and muscle
Divided into 2 pleural cavities by mediastinum
Mediastinum contains all thoracic organs except lungs
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Mediastinum
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Midline wall of tissue that contains heart and great
vessels, esophagus, trachea and thymus.
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Serous Membranes
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Thin slippery membrane lines body cavities not
open to the outside
parietal layer lines walls of cavities
 visceral layer covers viscera within the cavities
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Serous fluid reduces friction
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Pleural & Pericardial Cavities
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Visceral pleura clings to surface of lungs --- Parietal pleura
lines chest wall
Visceral pericardium covers heart --- Parietal pericardium lines
pericardial sac
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Peritoneum
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Visceral peritoneum --- serous membrane that covers the
abdominal viscera
Parietal peritoneum --- serous membrane that lines the
abdominal wall
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Abdominopelvic Regions &
Quadrants
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Describe locations of organs or source of pain
Tic-tac-toe grid or intersecting lines through navel
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Medical Imaging
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Allows visualization of structures without
surgery
Useful for confirmation of diagnosis
Examples of imaging techniques
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Conventional Radiography
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A single burst of xrays
Produces 2-D image on
film
Known as radiography or
xray
Poor resolution of soft
tissues
Major use is osteology
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Computed Tomography (CT Scan)
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Moving x-ray beam
Image produced on a
video monitor of a crosssection through body
Computer generated
image reveals more soft
tissue detail
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kidney & gallstones
Multiple scans used to
build 3D views
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Digital Subtraction
Angiography(DSA)
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Radiopaque material
injected into blood vessels
Before and after images
compared with a computer
program
Image of blood vessel is
shown on a monitor
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Ultrasound (US)
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High-frequency sound waves
emitted by hand-held device
Safe, noninvasive & painless
Image or sonogram is
displayed on video monitor
Used for fetal ultrasound and
examination of pelvic &
abdominal organs, heart and
blood flow through blood
vessels
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Magnetic Resonance Imaging (MRI)
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Body exposed to highenergy magnetic field
Protons align themselves
relative to magnetic field
Pulse of radiowaves used
to generate an image on
video monitor
Can not use on patient
with metal in their body
Reveals fine detail within
soft tissues
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Positron Emission
Tomography(PET)
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Substance that emits
positively charged particles
is injected into body
Collision with negatively
charged electrons in tissues
releases gamma rays
Camera detects gamma rays
& computer generates
image displayed on monitor
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