Transcript psorisis power point

psoriasis



Definition: is a chronic, sometimes acute , noncontagious common condition of the skin
scaly disease of the skin , characterized by welldefined, pink or dull red
lesions covered with silvery scales. The edge of
the lesion is sharply delineated, and gentle
scraping of the lesion will produce mica- like
scales.
Etiology of the disease





There is a genetic predisposition to psoriasis in one- fourth of
psoriatic patients. type of autoimmune)
It mostly develops between 10 and50 years old.
It’s mainly located on scalp, folds of the elbows and knees, and
the genito anal region.
They mostly develop at the side of vaccination., scratch marks ,
surgical incisions, or in skin test sites, and may be precipitated by
shock and noise.
Normally, the time between manufacturing and shedding skin
cells is about28-35 days. In psoriasis, the process is
approximately7 times faster, but the rate at which old cell slough
off is unchanged. this causes cells to build up on the skins
surface, forming thick patches, or placques,of red lesion covered
with flaky, silvery scales




Continue
Normal epidermal turnover is 25 to 30 days; in
psoriasis plaque skin, it is 3 to 4 day or less.
Duration of psoriasis; is variable, lesion may last
a life time or it could disappear quickly. The
course of the disease is marketed by
spontaneous exacerbation and remission.
. It has a tendency to become chronic.
Hot weather and sunlight improve the condition
,and cold weather causes a considerable
worsening




Types :
Acute guttata psoriasis: attack for about 17% of
psoriatic patients. It is most common in children,
and is characterized by many small lesions more
or less distributed over the body( it may follow
streptococcal tonsillitis.
Pustular psoriasis: is localized in the palm and
soles. Defined as raised bumps on the skin that
are filled with pus (pustules ) ,skin under and
around these bumps is red.
Psoriasis plaque
treatment



Potent agents should not be used until they are
deemed necessary. A simple case of psoriasis may
become worse and may lead to general exfoliative
dermatitis, in which a general erythema scale,
covering the entire body develops.
Acute cases with severely erythematous, local
therapy should be soothing and non- irritating.
A blend of,non-medicated cream should be used; as
the acute process subside and the usual thick-scaled
plaques appear, then more potent medication can
be used
Plaque psoriasis
An occlusive bandage be applied prior application of
medicinal agent penetration of drug through thick
plaque is difficult unless the area is abraded or occluded
 The plaque in psoriasis should be removed prior
application of medical agents to allow penetration of
the substances
 The use of cytostatic agents are sometimes very
effective
 Topically applied corticosteroids and systematically
administered methotexateare prescription drugs
Ingredients in OTC prducts





keratolytics: salicylic acid 2 to 10 %
tar products: combination of tar and keratolytics
( tar products enhance the beneficial effect of
sunlight)
antihistaminic: to alleviate pruritus, and reduce
emotional factors.
Tretinoin
Prescription drugs : systemically administered
methotrexate


Scalp psoriasis vs. seborrheic dermatitis:
What's the difference?
Q.How does a doctor tell the difference
between scalp psoriasis and seborrheic
dermatitis of the scalp?
continue



.
Scalp psoriasis and seborrheic dermatitis of the scalp can be
difficult to differentiate.
Both are common conditions that affect the scalp.
In addition, they share similar symptoms, such as itchy, red, scaly
skin.
Fortunately, they also share some similar treatments, such as
medicated shampoos.
However, scalp psoriasis tends to be more resistant than does
seborrheic dermatitis to these treatments,

The scales of psoriasis are thicker and somewhat
drier in appearance than are the scales of
seborrheic dermatitis. In addition, psoriasis
usually affects more than one area of the body.
So if you have scalp psoriasis, you may also have
mild psoriasis on your elbows, knees, buttocks
or fingers.

There is no single test to confirm a diagnosis of
psoriasis or seborrheic dermatitis. A diagnosis is
usually made with a visual examination of the
affected skin. In rare cases, a skin biopsy may be
needed to differentiate between the two
disorders.







Scalp psoriasis Signs and symptoms
Red patches of skin covered with silvery scales
Dry, cracked skin that may bleed
Itching, burning or soreness
Treatment Over-the-counter medicated shampoos,
such as those containing ketoconazole, tar, pyrithione
zinc, selenium sulfide or salicylic acid
Topical solutions, creams or ointments, such as tar
products, corticosteroids or vitamin D analogues
Light therapy






Seborrheic dermatitis of the scalp Patchy scaling
or thick crust on the scalp
Yellow or white scales that may attach to the hair
shaft
Red, greasy skin covered with flaky white or
yellow scales
Small, reddish-brown bumps
Itching or soreness
Skin flakes o



Treatment
Over-the-counter medicated shampoos, such as
those containing ketoconazole, tar, pyrithione
zinc, selenium sulfide or salicylic acid
Topical solutions or creams such as
hydrocortisone cream




There is no single test to confirm a diagnosis of
psoriasis or seborrheic dermatitis. A diagnosis is usually
made with a visual examination of the affected skin. In
rare cases, a skin biopsy may be needed to differentiate
between the two disorders
Summary.
Treatment of psoriasis, after proper giagnosis should be
initiated in a conservative manner.
Potent agents reserved when the condition does not
respond.
Thank you for your attention