The Nervous system
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Transcript The Nervous system
The Nervous system
The nerve cell is the basic unit of communication in the
vertebrate nervous system
Components of the Nervous
System
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Figure 11.1
Three Classes of neurons
The Neural circuit consists of
Sensory neurons
Interneuron (CNS)
receptor for stimulus
integrate signals
Motor neuron
transfer signal to effector (muscle)
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Types of Neurons in the
Nervous System
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Figure 11.2
Anatomy of a Neuron
Cell body: functional
portion
Dendrites: short
extensions that receive
signals
Axon: long extension that
transmits impulses
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How does a neuron hold and
move info?
A neuron at rest has a voltage difference
across the plasma membrane called a
resting voltage potential
An action potential (AP) is when this charge
across the membrane is briefly switched
The action potential moves down the
membrane at a rapid pace.
Ap can move faster over mylenated portions
is called saltatory conduction
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Myelinated Neuron
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Figure 11.7a
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Maintenance of the Resting
Membrane Potential
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Figure 11.3
Resting Membrane Potential,
Graded Potentials, and an
Action Potential
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Figure 11.4
The Nerve Impulse Is a
Bioelectrical Signal
The sodium-potassium pump uses ATP to transport sodium ions out
and potassium ions in
The inside of a resting neuron has a negative charge relative to the
outside
An action potential is a reversal and restoration of the charge
difference across the membrane
The sodium-potassium pump restores the original distribution of ions
Action potentials are all-or-none events
A neuron cannot fire during the refractory period
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How does a signal move
from one neuron to another?
A synaptic cleft divides 2 neurons
The AP will not move across the synaptic cleft
Neuro transmitters are released by the signal
cell to the receiver cell
Move by diffusion
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Transfer of Information from
Neuron to Target
Synaptic transmission:
Release of neurotransmitter: graded potential achieved
Effects of neurotransmitter:
Excitatory: depolarize postsynaptic cell
Inhibitory: hyperpolarize postsynaptic cell
Role of postsynaptic neuron: integrate and process
information
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Types of chemical synapse
Acetylcholine: neuromuscular junctions,
glands, brain and spinal cord
Norepinepherine: affects brain regions
concerned with emotions, dreaming
From table 11.1
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The nervous System
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Paths of information flow
Signals between the
brain and spinal cord
move to the body
regions by nerves
Sensory nerves move a
signal towards the brain
and spinal cord
Motor neurons move a
signal from the brain or
spinal cord to the body
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Divisions of the nervous
System
Central nervous system
CNS
Is the brain and spinal
cord
Peripheral nervous
system
PNS
all nerves that carry
signals to and from the
CNS
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Parts of the PNS
Sensory Division carries info to the brain
and spinal cord.
Motor Division carries info from the brain to
the bodies effectors (things that do the work)
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The Motor division of the
PNS has 2 divisions
Somatic nerves relay
commands to and from
skeletal muscle
Autonomic nerves
send signals to and
from smooth muscles
Voluntary control
Involuntary control
Sympathetic
Parasympathetic
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The autonomic divisions
Parasympathetic
Sympathetic
slow down the body
activity when the body
is not under stress
Rest and digest
increase overall body
activity during times of
stress, excitement or
danger
fight or flight
response
hormone epinephrine
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Fig 11.12
Sympathetic and
Parasympathetic
Are Antagonistic
Work towards the automatic, subconscious
maintenance of homeostasis.
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Parts of CNS
Components of the CNS
Spinal cord
31 pair of spinal nerves
Grey matter
White matter
Controls some reflex
actions like bladder
emptying
Brain parts
Hindbrain
Midbrain
Forebrain
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medulla oblongata
cerebellum
pons
cerebrum
thalamus
hypothalamus
Ventricles of the Brain and
Circulation of Cerebrospinal
Fluid
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Figure 11.13
Brain: Major Divisions
Hindbrain: coordinates basic, automatic, vital
functions
Medulla oblongata: controls automatic functions
of internal organs
Cerebellum: coordinates basic movements
Pons: aids flow of information
Midbrain: coordinates muscles related to vision
and hearing
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Brain: Processes and Acts
on Information
Forebrain: receives and integrates information concerning
emotions and conscious thought
Hypothalamus: helps regulate homeostasis
Thalamus: receiving, processing, and transfer center
Limbic system: neuronal pathways involved in emotions
and memory
Cerebrum/cerebral cortex: higher functions
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Sleep
Sleep center: reticular activating system
(RAS)
Stages: based on electroencephalograms
(EEGs):
Stage 1: transitional, random small waves on EEG
Stage 2: skeletal muscles relax, little eye or body
movement, EEG shows sleep spindles
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Sleep (cont.)
Stage 3: heart and respiration slower, EEG shows slow
wave sleep
Stage 4: difficult to awaken, heart and respiration
slowest, body temperature decreased
REM (rapid eye movement) sleep: dreaming, EEG same
as awake
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Limbic System: Emotions of
Fear, Anger, Sorrow, Love
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Figure 11.19
Memory: Storing and
Retrieving Information
Short term: working memory, information
from previous few hours
Long term: information from previous days to
years
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Other parts of the CNS
The two cerebral hemispheres communicate
through the corpus collosum
left verbal skills
right nonverbal skills such as music math, abstract
Brain cavities and Canals
cerebrospinal fluid surrounds and fills in cavities in the
brain
Blood Brain barrier- controls what moves into the brain.
Will prevent infections.
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Our state of consciousness
The CNS governs sleeping, dozing,
daydreaming and full alertness
neurons of the reticular activating system
RAS control the changing levels of
consciousness by releasing serotonin.
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Memory
Association is the
linkage of information
to structural and
chemical changes
short term- few bits
lasts a couple of hours
Long term- permanent
and limitless
The most important info
goes rapidly into long
term storage
memory is stored in a
form resistant to
degradation
Possibly caused by
changes in synapses.
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Tips on studying
Concentrate on what you study.
Minimize interference.
Study takes time.
Break material into smaller portions.
Rephrase materials in your own words.
Test yourself to see what you know.
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Primary somatosensory and
motor areas of cerebral
cortex
Disorders of the nervous
system
Trauma
Infections
Transmission and synaptic defects.
Abnormal growth
Headache
Tumors
Stroke
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Psychoactive Drugs
Action: affects higher brain functions
Psychological dependence: user craves the
feeling associated with the drug
Tolerance: takes more of the substance to
achieve the same affect
Addiction: the need to continue obtaining and
using a substance; no free choice
Withdrawal: physical symptoms that occur upon
stopping the drug
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Know what the parts of the
brain do
Brain parts
medulla oblongata
cerebellum
pons
cerebrum
thalamus
hypothalamus
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seratonin
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Just a reminder to talk
about drugs that
interact with brain.
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