Transcript Chapter 2: The Brain and Behavior

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Chapter 2
Chapter 2
Brain and Behavior
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Neuron and Its Parts
• Neuron: Individual nerve cell
– Dendrites: Receive messages from other neurons
– Soma: Cell body; body of the neuron
– Axon: Fiber that carries information away from the cell
body
– Axon Terminals: Branches that link the dendrites and
somas of other neurons
Figure 2.1
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FIGURE 2.1 A neuron, or nerve cell. In the right foreground you can see a nerve cell fiber in cross
section. The upper left photo gives a more realistic picture of the shape of neurons. Nerve
impulses usually travel from the dendrites and soma to the branching ends of the axon. The nerve
cell shown here is a motor neuron. The axons of motor neuron stretch from the brain and spinal
cord to muscles or glands of the body.
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The Nerve Impulse
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Resting Potential: Electrical charge of an inactive neuron
Threshold: Trigger point for a neuron’s firing
Action Potential: Nerve impulse
Negative After-Potential: When a neuron is less willing to
fire
Figure 2.2
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FIGURE 2.2 Electrical probes placed inside and outside an axon measure its activity. (The
scale is exaggerated here. Such measurements require ultra-small electrodes, as described
later in this chapter.) The inside of an axon at rest is about -60 to -70 millivolts, compared
with the outside. Electrochemical changes in a neuron generate an action potential. When
positively charged sodium ions (Na+) rush into the cell, its interior briefly becomes positive.
This is the action potential. After the action potential, positive potassium ions (K+) flow out of
the axon and restore its negative charge (see Fig. 2.3 for further explanation).
Figure 2.3
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FIGURE 2.3 The electrical charge inside an axon is normally negative. The fluid surrounding an
axon is normally positive. As an action potential passes along the axon, these charges reverse so
that the interior of the axon briefly becomes positive. This process is described in more detail in
Figure 2.4.
Figure 2.4
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FIGURE 2.4 The interior of an axon. The right end of the top axon is at rest. Thus, it has a
negative charge inside. An action potential begins when ion channels open and sodium ions
(Na+) rush into the axon. In this drawing, the action potential would travel from left to right along
the axon. In the lower axon, the action potential has moved to the right. After it passes, potassium
ions (K+) flow out of the axon. This quickly renews the negative charge inside the axon, so it can
fire again. Sodium ions that enter the axon during an action potential are pumped out more slowly.
Removing them restores the original resting potential.
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Synapses
 Messages from one neuron to another pass over a
microscopic gap called a synapse
– Synapse: Microscopic gap between two neurons over
which messages pass
Figure 2.5
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FIGURE 2.5 A highly magnified view of a synapse. Neurotransmitters are stored in tiny sacs
called synaptic vesicles (VES-ihkels). When a nerve impulse reaches the end of an axon, the
vesicles move to the surface and release neurotransmitters. These molecules cross the synaptic
gap to affect the next neuron. The size of the gap is exaggerated here; it is actually only about
one millionth of an inch. Some transmitter molecules excite the next neuron, and some inhibit its
activity.
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Neurotransmitters
• Chemicals that alter activity in neurons; brain chemicals
– Acetylcholine: Activates muscles
– Dopamine: Muscle control
– Serotonin: Mood and appetite control
• Receptor Site: Areas on the surface of neurons and
other cells that are sensitive to neurotransmitters
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Neural Regulators
• Neural Peptides: Regulate activity of other neurons
– Enkephalins: Relieve pain and stress; similar to
endorphins
– Endorphins: Released by pituitary gland; also help to
relieve pain
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Nerves and Neurons
• Nerves: Large bundles of axons and dendrites
• Myelin: Fatty layer of tissue that coats axons
– Multiple Sclerosis (MS) occurs when myelin layer is
destroyed; numbness, weakness, and paralysis occur
• Neurilemma: Thin layer of cells wrapped around axons
outside brain and spinal cord; forms a tunnel where
damaged fibers go as they repair themselves
• Neurogenesis: Production of new brain cells
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Neural Networks
• Central Nervous System (CNS): Brain and spinal cord
• Peripheral Nervous System: All parts of the nervous
system outside of the brain and spinal cord
– Somatic System: Links spinal cord with body and
sense organs; controls voluntary behavior
– Autonomic System: Serves internal organs and
glands; controls automatic functions such as heart
rate and blood pressure
Figure 2.6
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FIGURE 2.6 (a) Central and peripheral nervous systems. (b) Spinal nerves, cranial nerves, and
the autonomic nervous system.
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Two Divisions of the Autonomic System
• Sympathetic: Arouses body; emergency system
• Parasympathetic: Quiets body; most active after an
emotional event
Figure 2.8
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FIGURE 2.8 Sympathetic and parasympathetic branches of the autonomic nervous system. Both
branches control involuntary actions. The sympathetic system generally activates the body. The
parasympathetic system generally quiets it. The sympathetic branch relays its messages through
clusters of nerve cells outside the spinal cord.
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The Spinal Cord
• Spinal Nerves: 31 of them; carry sensory and motor
messages to and from the spinal cord
• Cranial Nerves: 12 pairs that leave the brain directly;
also work to communicate messages
Figure 2.7
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FIGURE 2.7 Subparts of the nervous system.
Figure 2.9
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FIGURE 2.9 A sensory-motor arc, or re- flex, is set in motion by a stimulus to the skin (or other
part of the body). The nerve impulse travels to the spinal cord and then back out to a muscle,
which contracts. Such reflexes provide an “automatic” protective device for the body.
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Researching the Brain
• Ablation: Surgical removal of parts of the brain.
• Deep Lesioning: A thin wire electrode is lowered into a
specific area inside the brain. Electrical current is then
used to destroy a small amount of brain tissue.
• Electrical Stimulation of the Brain (ESB): When an
electrode is used to activate target areas in the brain.
• Electroencephalograph (EEG): Detects, amplifies, and
records electrical activity in the brain.
Figure 2.10
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FIGURE 2.10 The functions of brain structures are explored by selectively activating or
removing them. Brain research is often based on electrical stimulation, but chemical
stimulation is also used at times.
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Researching the Brain (cont'd)
• Computed Tomographic Scanning (CT): Computerenhanced X-ray image of the brain or body
• Magnetic Resonance Imaging (MRI): Uses a strong
magnetic field, not an X-ray, to produce an image
• Functional MRI (fMRI): MRI that also records brain
activity
• Positron Emission Tomography (PET): Computergenerated color image of brain activity, based on glucose
consumption in the brain
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Cerebral Cortex
• Definition: Outer layer of the cerebrum
• Cerebrum: Two large hemispheres that cover upper part
of the brain
• Corticalization: Increase in size and wrinkling of the
cortex
• Cerebral Hemispheres: Right and left halves of the
cortex
• Corpus Callosum: Bundle of fibers connecting cerebral
hemispheres
Figure 2.21
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FIGURE 2.21 The left and right brain have different information-processing styles. The left
brain focuses on the small details; the right gets the big pattern.
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Split Brains
• Corpus Callosum is cut; done to control severe epilepsy
(seizure disorder).
• Result: The person now has two brains in one body.
• This operation is rare and is often used as a last resort.
Figure 2.19
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FIGURE 2.19 Basic nerve pathways of vision. Notice that the left portion of each eye connects
only to the left half of the brain; likewise, the right portion of each eye connects to the right brain.
When the corpus callosum is cut, a “split brain” results. Then visual information can be sent to just
one hemisphere by flashing it in the right or left visual field as the person stares straight ahead.
Figure 2.20
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FIGURE 2.20 A circle is flashed to the left brain of a split-brain patient, and he is asked what he
saw. He easily replies, “A circle.” He can also pick out the circle by merely touching shapes with
his right hand, out of sight behind a screen. However, his left hand can’t identify the circle. If a
triangle is flashed to the patient’s right brain, he can’t say what he saw (speech is controlled by
the left hemisphere). He also can’t identify the triangle by touch with the right hand. Now,
however, the left hand has no diffi- culty picking out the triangle. In other tests, the hemispheres
reveal distinct skills, as listed above the drawing.
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Central Cortex Lobes
• Occipital: Back of brain; vision center
• Parietal: Just above occipital; bodily sensations such as
touch, pain, and temperature
• Temporal: Each side of the brain; auditory and language
centers
• Frontal: Movement, sense of smell, higher mental
functions
– Contains motor cortex; controls motor movement
Figure 2.22
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Figure 2.23
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FIGURE 2.23 The lobes of the cerebral cortex and the primary sensory, motor, and association
areas on each. The top diagrams show (in cross section) the relative amounts of cortex
“assigned” to the sensory and motor control of various parts of the body. (Each cross section, or
“slice,” of the cortex has been turned 90 degrees so you see it as it would appear from the back
of the brain.)
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When the Brain Fails to Function Properly
• Association Cortex: Combine and process information
from the five senses
• Aphasia: Speech disturbance resulting from brain
damage
Figure 2.18
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When the Brain Fails to
Function Properly (cont'd)
• Broca’s Area: Related to language and speech
production
– If damaged, person knows what s/he wants to say but
can’t say the words
• Wernicke’s Area: Related to language comprehension
– If damaged, person has problems with meanings of
words, NOT pronunciation
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Subcortex
• Hindbrain (Brainstem)
– Medulla: Connects brain with the spinal cord and
controls vital life functions such as heart rate and
breathing
– Pons (Bridge): Acts as a bridge between medulla and
other structures
• Influences sleep and arousal
– Cerebellum: Located at base of brain
• Regulates posture, muscle tone, and muscular
coordination
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Subcortex: Reticular Formation (RF)
• Lies inside medulla and brainstem
– Associated with alertness, attention and some
reflexes (breathing, coughing, sneezing, vomiting)
• Reticular Activating System (RAS): Part of RF that keeps
the cortex active and alert
• Its alarm clock
Figure 2.25
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FIGURE 2.25 This simplified drawing shows the main structures of the human brain and describes
some of their most important features. (You can use the color code in the foreground to identify
which areas are part of the forebrain, midbrain, and hindbrain.)
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Forebrain
• Structures are part of Limbic System: System within
forebrain closely linked to emotional response
– Thalamus: Relays sensory information to the cortex;
switchboard
– Hypothalamus: Regulates emotional behaviors and
motives (e.g., sex, hunger, rage, hormone release)
– Amygdala: Associated with fear responses
– Hippocampus: Associated with storing memories;
helps us navigate through space
Figure 2.26
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FIGURE 2.26 Parts of the limbic system. Although only one side is shown here, the hippocampus
and the amygdala extend out into the temporal lobes at each side of the brain. The limbic system
is a sort of “primitive core” of the brain strongly associated with emotion.
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Endocrine System
• Glands that pour chemicals (hormones) directly into the
bloodstream or lymph system
– Pituitary Gland: Regulates growth via growth
hormone
• Too little means person will be smaller than
average
– Hypopituitary Dwarfs: As adults, perfectly
proportioned but tiny
• Too much leads to giantism
– Excessive body growth
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Endocrine System (cont'd)
• Acromegaly: Enlargement of arms, hands, feet, and
facial bones
– Too much growth hormone released late in growth
period
• Andre the Giant
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Endocrine System Concluded
• Pineal Gland: Regulates body rhythms and sleep cycles.
– Releases hormone melatonin, which responds to
daily variations in light.
• Thyroid: In neck; regulates metabolism.
– Hyperthyroidism: Overactive thyroid; person tends to
be thin, tense, excitable, nervous.
– Hypothyroidism: Underactive thyroid; person tends to
be inactive, sleepy, slow, obese.
Figure 2.27
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The Adrenal Glands
• Adrenals: Arouse body, regulate salt balance, adjust
body to stress, regulate sexual functioning; located on
top of kidneys
– Releases epinephrine and norepinephrine (also
known as adrenaline and noradrenaline)
• Epinephrine arouses body; is associated with fear
• Norepinephrine arouses body; is linked with anger
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The Adrenal Glands (cont'd)
• Adrenal Medulla: Source of epinephrine and
norepinephrine
• Adrenal Cortex: Produces hormones known as corticoids
– Regulate salt balance
– Deficiency in some types will cause powerful salt
cravings
– Oversecretion of adrenal sex hormones can cause
virilism: exaggerated male characteristics (Bearded
woman)
– May also cause premature puberty (full sexual
development in childhood) if occurs early in life
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Handedness
• Preference for right or left hand
• Dominant Hemisphere: Applies to side of person’s brain
that produces language
• Lateralization: Difference in the abilities of the brain’s
hemispheres
Figure 2.29
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FIGURE 2.29 Research suggests that the hand position used in writing may indicate which brain
hemisphere is used for language.