Transcript Document
• >Medical information on the web - Questions and Answers. • >Shortcuts with Powerpoint* • >Using touchscreens to speed up dictation* Computer annoyances: Spyware, • >popups, Viruses, Worms* Managing Your Email Searching strategies • >Robotics/artificial intelligence in medicine The Internet as the • >Megamacroscope - Microscope/Web historical analogies The Tablet PC. • >Human based computing and medicine • >Wireless applications in medicine. • >Evidence based nephrology and clinical practice guidelines online. >Medical information on the web - Questions and Answers. >Shortcuts with Powerpoint* >Using touchscreens to speed up dictation* Computer annoyances: Spyware, >popups, Viruses, Worms* Managing Your Email Searching strategies Robotics/artificial intelligence in medicine The Internet as the Megamacroscope - Microscope/Web historical analogies The Tablet PC. Human based computing and medicine Wireless applications in medicine. Evidence based nephrology and clinical practice guidelines online. >Medical information on the web - Questions and Answers. >Shortcuts with Powerpoint* >Using touchscreens to speed up dictation* Computer annoyances: Spyware, >popups, Viruses, Worms* Managing Your Email Searching strategies Robotics/artificial intelligence in medicine The Internet as the Megamacroscope - Microscope/Web historical analogies The Tablet PC. Human based computing and medicine Wireless applications in medicine. Evidence based nephrology and clinical practice guidelines online. Part 1 Medical information on the web Questions and Answers. Shortcuts with Powerpoint* Using touchscreens to speed up dictation* Computer annoyances: Spyware, popups, Viruses, Worms* Managing Your Email Searching strategies Robotics/artificial intelligence in medicine The Internet as the Part 2 Megamacroscope - Microscope/Web historical analogies The Tablet PC. Human based computing and medicine Wireless applications in medicine. Evidence based nephrology and clinical practice guidelines online. Medical information on the web Questions and Answers Google – Images Newsdesk Pubmed Uptodate Full Text journals Shortcuts with Powerpoint Changing backgrounds and layouts Add a picture Get rid of the background Split the slide Print – avoid the mess F5 – look like you know what you’re doing Dual screens Issues in Nephrology Animation SHP (Scr homology EPO is a chemokine ligand GATA-1 blocks apoptosis through domain phosphatase) is a EPO that binds two receptors. EPO increased BCl-cL and to EPO Cytoplasmic enzyme FASL That dephosphorylates and turns off the EPO Janus Kinase (JAK) Receptor. A congenital FAS defect–indocking this enzyme Phosphorylates the receptor was present in sites. Eero Mäntyranta who won JAK2 JAK2 a gold medal in the 1964 JAK2 JAK2 Olympics. His hemoglobin P P SH2-STAT Picture SH2-STAT 23.1 g/dL. transducer and STAT(Signalwas P P P P Fas combines with FaDD. The DD stands for “death domain”. Recruit s proteolytic caspases The Fas ligand is upregulated by Transcription) as a modem Tumor necrosis factor PandP P P FADD interferon – hence a mechanism GATA (Guanadine-Adenine-thymidineSrc homology protein where inflammation Adenine)blunts a transcription factor that selects CASPASE erythropoiesis ACTIVATION the proper DNA sequence for transcription. EPO block erythroid apoptosis GATA-1 GATA-1 GATA-1 Hypoxi Normoxia a VHL HIF-1 Ubiquitin induced degradation EPO Erythro NUCLEUS O2 NORMOXIA PROLYL HYDROXYLASE Fe++ OH OH HIF ASPARAGINYL HYDROXYLASE P300 Coactivator Proteasome Amino Acids TRANSCRIPTION ACTIVATION NUCLEUS COBALT O2 NO Fe++ OH OH CADMIUM HIFß HNF4 P300 Iron deficiency CREB Transcription on EPO Gene P300 Coactivator Proteasome Amino Acids NITRIC OXIDE, IRON DEFCIENCY AND COBALT RESCUE HIF BUT CADMIUM BLOCKS AT THE DNA LEVEL TRANSCRIPTION ACTIVATION NUCLEUS HYPOXIA PROLYL HYDROXYLASE HIFß HNF4 P300 CREB Transcription on EPO Gene Proteasome EPO EPO popups, Viruses, Worms* Managing Your Email Searching strategies Popups Popups are obnoxious Popups – Worms – Viruses – Spyware and Spam Popups – Google Worms – Virus programs – Mcafee and Norton Spyware – Webroot and Addaware – try to prevent – check often Spam – anti spam programs – Norton and Spam Bayes. MS Outlook 2003 E-mail filtering Organize – Friends, Business, Research, Humor, Personal Setting your rules Editing rules Outlook is limited Eudora is better Invaluable Be careful sending patients e-mail Record – permanent – cannot be changed Dated – date must be recorded Must be in a central record Responsiveness – – E-mail: Doc, I am having chest pain and shortness of breath right now. What do I do? Hipaa compliant – – Encryption algorithms, Secure server The New Newsdesk Newsdesk 3.0 www.szf.com Faster Easier to execute Send e-mail Send to PDA http://www.medicalresources.net The Renalworld Family http://www.links.nephron.com http://www.ifkf.net http://www.renalworld.com http://www.szf.com http://www.medicalresources.net Advanced Powerpoint Visual Basic Tests Quizes Popups Height Weight BMI Reset Calculate Calculate your MDRD GFR Age 1.6 Creatinine MDRD 36 Reset ml/min/1.73m2 Calculate MS Powerpoint slide © 2003 Stephen Z. Fadem, M.D. and Brian Rosenthal. All rights reserved Ref: Ann Intern Med. 1999, Mar 16(6):461-70, JASN 2000, Sep (11): A0828 NKF K/DOQI Guidelines – Chronic Kidney Disease Begin Quiz Question 1 JNC VII recommends medication when Next Question 2 Check all that apply: Diltiazem is a vasodilator decreases cardiac resistance increases cardiac resistance increases heart rate Next Question 3 True or false: A systolic increase of 20 mm or a diastolic of 10 mm doubles cardiac risk when BP > 115/75 Next Question 4 The following are true 1 1. Diltiazem in the Nordil study was not designed for nightly control 2 2. Diltiazem dose in Nordil was > 360 mg 3 3. Diltiazem decreases stroke 4 4. Diltiazem did not significantly increase cardiovascular risk Next Question 5 It is normal for blood pressure to be the same in the morning and in the evening Next Question 6 Myocardial infarctions occur most often: Next Question 7 Choose the best answer Diltiazem LA Next Question 8 True or False It is recommended that we treat BP of > 130/80 with medication in diabetics and patients with kidney disease Next Your score You scored a 8 / 8 on this test. Please print out your certificate on the next slide. View Certificate Name___________________________________ passed this test. 50 million Americans are hypertensive. Today, I have learned more about one of the classes of therapeutic agents used to treat hypertension, and am now more familiar with the new Guidelines published by the Seventh Joint National Committee on Hypertension Physician Signature_________________Date___________ Printed name_________ THE END