Transcript Bruker Optics

Introduction to Bruker Optics,
NSC Mid Year Sales Meeting Sept 2007,
By Muhammad Saeed
Bruker Optics
• offers the complete product line
• is leading in technology and innovations
• is steadily growing
• is the only European supplier
• is world wide present
FT-IR FT-NIR Raman Terahertz TD-NMR
Our products are based on
molecular spectroscopy
Bruker Group
Founded in 1960 in Germany
Bruker world wide today :
> 3000 Employees
> 25 Locations
> 50 Sales and Service Offices
> 700 Mio. $ Revenue
Bruker Group
Company
Technology
X - Ray Fluorescence and Diffraction
Mass Spectrometry
NMR-Spectrometry
Optical Spectroscopy
Bruker Optics - we offer solutions
Process Monitoring
Laboratory Analysis
Research & Development
Life Science
Academics
Quality Control
Bruker Optics product line
Bruker is the only supplier with a complete product line
ALPHA
FT-IR
Spectrometer
TENSOR 27/37
FT-IR
Spectrometer
VERTEX 70/80
FT-IR
Spectrometer
IFS 125
FT-IR
Spectrometer
1.) Basic IR up to highest resolution spectrometer.
World record: The IFS 125 HR is the spectrometer with the highest
resolution in the market
World record: The Alpha is world’s smallest FTIR Spectrometer.
Bruker Optics product line
Bruker is the only supplier with a complete product line
HELIOS
HYPERION
Imaging
2.) Microscopy
-Sample compartment microscope
-IR imaging microscope
-IR microscope
-Raman microscope
Bruker Optics product line
Bruker is the only supplier with a complete product line
MPA
3.) Near IR spectrometer
-Lab QA/QC
-Process
MATRIX
Industry
Bruker Optics product line
Bruker is the only supplier with a complete product line
RAM II
RFS 100
4.) Complete Raman product line
FT-Raman module
FT-Raman spectrometer
Dispersive Raman process
Dispersive Raman microscope
SENTINEL
Bruker Optics product line
Bruker is the only supplier with a complete product line
minispec
5.) Plus
Minispec
TeraHertz
Spectrographs
TeraView
Spectrographs
Bruker Optics product line
Bruker is the only supplier with a complete product line
PAT
Food
6.) Solutions for dedicated markets:
- Process
Polymer
Bruker Optics product line
Bruker is the only supplier with a complete product line
Proteomics
Microbiology
6.) Solutions for dedicated markets:
- Life Science
Tissue
Introduction
Bruker Opticsto FT-IR spectroscopy
Bruker Optics
Discovery of infrared light
In the year 1800 the astronomer Friedrich Wilhelm Herschel analyzed the spectrum of sunlight. Herschel created the
spectrum by directing sunlight through a glass prism so that the light was divided into its different colors. He measured
the heating ability of each color using thermometers with blackened bulbs. When he measured the temperature just
beyond the red part of the spectrum he noticed some kind of invisible radiation. Much to his surprise he found that the
area close to the red part (i.e. an area apparently devoid of sunlight) had the highest heating ability of all. Herschel
concluded that there must be a different kind of light beyond the red portion of the spectrum, which is not visible to the
human eye. This kind of light became known as “infrared” (below red) light.
Herschel then placed a water-filled container between the prism and thermometer and observed that the temperature
measured was lower than the one measured without the water. Consequently, the water must partially absorb the
radiation. In addition, Herschel could prove that depending on how the prism was rotated (i.e. depending on the spectral
range) the difference in the temperatures measured for each color varied. This was the beginning of infrared
spectroscopy.
Infrared spectroscopy measures the infrared light that is absorbed by a substance. This absorption depends on the
wavelength of the light.
Friedrich Wilhelm Herschel
(1738 - 1822)
The electromagnetic spectrum
The electromagnetic spectrum
Visible light and infrared light are two types of
electromagnetic radiation, but with different wavelengths, or
frequencies. In general, electromagnetic radiation is defined
by the wavelength  or the linear frequency . The
wavelength is the distance between two maxima on a
sinusoidal wave.
The frequency is the number of wavelengths per unit time.
Since all electromagnetic waves travel at the speed of light,
the frequency corresponding to a given wavelength can be
calculated as:
 = c/
According to the Plank’s Radiation Law, the frequency of
electromagnetic radiation is proportional to its energy.
E = h•
In infrared spectroscopy wavenumber is used to describe
the electromagnetic radiation. Wavenumber is the number
of wavelengths per unit distance. For a wavelength  in
microns, the wavenumber, ~, in cm-1, is given by
~ = 10000/
Sinusoidal wave of wavelength 
The electromagnetic spectrum
The electromagnetic spectrum
The electromagnetic spectrum
Interaction of radiation and matter
Interaction of radiation and matter
If matter is exposed to electromagnetic radiation, e.g. infrared light, the radiation can be absorbed, transmitted, reflected, scattered or undergo
photoluminescence. Photoluminescence is a term used to designate a number of effects, including fluorescence, phosphorescence, and Raman
scattering.
Matter
Photoluminescence
Incident light beam
Absorption
Transmission
Reflection
Scattering
Separation of spectral ranges
NIR
15,000 cm-1
MIR
4,000 cm-1
FIR
400 cm-1
5 cm-1
The working principle of an FT-IR spectrometer
Infrared light emitted from a source (e.g. a SiC glower) is directed into an interferometer, which modulates
the light. After the interferometer the light passes through the sample compartment (and also the sample)
and is then focused onto the detector. The signal measured by the detector is called the interferogram.
General FT-IR spectrometer layout
FT-NIR Spectrometer
MPA - Multi Purpose Analyzer
FT-NIR Spectrometer
MATRIX-I: Process Analysis in Diffuse Reflection
NIR Spectroscopy in the Food Industry
Qualification of Raw Materials
• Disinfecting Materials
• Detergents
• Aromas
• Milk Powder (liquid Milk)
• Thickening Agents
• Starches
• ....
NIR Spectroscopy in the Food Industry
Quantification of Ingredients
• Sugar Content in Water/juices
• Pure Yolk/Alcohol Content in Egg Liquor
• Moisture Content/Total Sugar in Marzipan
• Fat/Protein/Water/Mineral Salt in Sausages
• Fat/Water/Protein/sugar in Mayonnaise or in Chocolate
• Fat/Dry Matter in Ice Cream
• Caffeine in Black Tea
• Caffeine in Instant Coffee
• Bloom-Number in Gelatine
• Trans Fatty Acids in Edible Oils (MIR)
• Moisture/Protein/Starch/Ash/Raw Fiber in Cereals
• Moisture/Nicotine in Tobacco
• ....
NIR IN Polymer Chemistry
Applications
• Additives
(Antioxidants, Lubricants, Modifiers, ...)
• Filler
• physical Properties
(Density, Viscosity, ...)
• averaged Molecular Weight
• MFI (Melt Flow Index)
• Humidity
• Content of Carboxyl End Groups
• OH-Number
• Acid Number
• Monomer Content
...
NIR in Polymer Chemistry
•
•
•
•
•
•
•
•
Stabilizer Content
Content of Rest Monomer
Density
Viscosity
MIBK (Methyl-Isobutyl-Ketone)
WPE (Weight per Epoxy)
MBCI (Poly(Etherurethane)Diisocyanate)
Content of Total PE, PEP, PEEP and
Block-Co-Polymer
...
NIR Applications In Petrochemistry
• Octane Number (RON & MON)
• Flash Point
• Cloud Point
• Boiling Behavior
• Cooling Behavior
• Content of Aromates
...
NIR Applications of Pharmaceuticals
• Identification in the Receipt of Goods
• Quantification of
– active Materials
– auxiliary Materials
– Filler
in Powders, Capsules, Tablets or Phials
• Water Content in Powders
• Surveillance of Drying Processes
• Mixing
• Solvent Recovery
• Placebo/Verum Studies
• Wall Thickness of Capsules
• physical Properties (Hardness,
Brittleness, … )
NIR Application in Feed and Feed ingredients
The Feed and Feed Ingredients calibrations include feed for various animals
like ruminant, poultry, swine, horse and fish, as well as feed ingredients
like seeds, cereals, legumes, roughage and animal by-products.
Feed and
Feed Ingredients
Min %
Max %
R2
Moisture
2.1
21,6
0,952
36.000+
Oil
0.1
61.6
0.998
27.000+
Australia, SE Asia,
Protein
1.7
61.7
0.994
39.000+
Pakistan, India, China,
Fiber
0.1
36.5
0.974
15.000+
Ash
0.7
59.4
0.962
22.000+
Starch
0.1
77.5
0.988
6.000+
n
Origin
UK & Ireland, EU, USA,
Japan, Malaysia,
Peru, Argentina, Brazil
NIR (MPA) Advantages
Advantages
•
Fast (10 - 20 sec. typical)
•
No sample preparation, simple to operate
•
No waste, no pollution
•
Simultaneous determination of multiple
components per measurement
•
Highly precise and accurate
•
Measure through packaging
•
Transferable methods
•
Real time monitoring for process
Summary
• Very often the time consumption for the method
development is for HPLC and GC higher than
NIR
• The NIR analysis time is generally
much faster.
• Mostly installation and maintenance-costs for
in-line- & off-line application is much lower for
NIR.
• NIR = cost effective!
Competition
Bruker Optics
Competition
FOSS = giant
Founded in 1956, >50 years
exper.
1100 employees for Agri
applications worldwide, 300
service & appl. staff
Present in 21 countries
Perfect marketing and market
knowledge
100++ distributors
Created “agri” standards
Competition
FOSS:
6500/5000 will die in 2007
Still problems with InfraXact
Old fashioned XDS is promoted:
„XDS is the latest & outstanding
technology. In the past only the high
priced Pharma customers have had
access. Now it is available for
everybody.“
FOSS is getting more aggressive also in
pricing
FOSS is in trouble – use it now!
Bruker Optics
Competition
THERMO:
Currently very active!
Focus on Pharma/PAT
Attacks classical
BRUKER markets
(non-agri)
Still relatively weak in
NIR, but THERMO is
a “sleeping shark”
Competition
THERMO Strategy:
Offering full options at low price
Engineering is weak
Our answer:
You need to know our USPs
adapted to the customers needs
Demonstrate the value of MPA for
the dedicated customer application
NIR: Quality beats price!
Competition
BÜCHI:
Focus on Agri and Grain
Cross selling
Active in limited number of countries (now
+US)
ABB:
Focus on Process and Dairy
Strong in Petro & all kind of OEMs
Strategy for the Key Markets
Strategy for Chemistry Applications
• Endless number of
applications are possible:
OH, acid number, QA/QC, inline & off-line
• High benefits of NIR by
replacing HPLC
• MPA = blockbuster
• Our sales structure fits
perfectly to this market
(solving applications on site)
• Bio fuels are coming!
Strategy for Polymer Applications
•Most Key Accounts are still OPEN like
SABIC.
•Biggest margins could be earn by
developing applications.
Strategy for Pharma Applications
•
All world’s biggest companies
are using Bruker’s MPA.
•
Pharma could be best future
prospective.
•
Applications:
STILL: raw ID & tablet testing
(by MPA)
Strategy for PetroChemistry Applications
•Saudi ARAMCO could be big customer
and we can make good margin.
•Need to work very closly.
•NSC already involved and have done
applications.
Strategy for F & F (Food & Agri) Applications
•The market still OPEN.
•Big Companies(Provimi,
Degussa, Addiseo, Nestlé, …) now
using Bruker’s systems which
could be useful for F&F business
in KSA.
•The Dairy Companies still using
old techniques which is good
news for us.
•Markets are ready for us. We are
highly welcome!!
To Do List
Bruker = Market Leader
We create the standards
(in non-agri)
Others will copy our success:
Save your market shares
Diversify – put not all eggs in
one basket
To Do List
Put more efforts in the
chemical market
Promote INGOT
Communicate (via M.Saeed)
– Knowledge & expertise is
getting more and more
important
Do not hesitate to ask for
support
One final remark about the future SM
Thank you very much!
www.brukeroptics.com