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E-poster Number 197 E-Poster Number Home Parenteral Nutrition: the experience of a Tertiary Hospital in São Paulo, Brazil. Mariana Hollanda Martins da Rocha, Andre Dong Won Lee, Maria Carolina Gonçalves Dias, Dan Linetzky Waitzberg, Lidiane Aparecida Catalani, Paula Machado Guidi, Natalia Diniz Micheloni, Rafael Antonio Arruda Pecora, Igor Lepski Calil, Flavio Henrique Ferreira Galvão, Luiz Augusto Carneiro D'Albuquerque ([email protected]) Gastroenterology Department, Digestive Surgery Division, University of Sao Paulo Medical School, São Paulo, Brazil xxxxxxx INTRODUCTION Short bowel syndrome (SBS) is characterized by nutrient malabsorption and occurs following surgical resection, congenital defect, or disease of the bowel. The severity of SBS depends on the length and anatomy of the bowel resected and the health of the remaining tissue. In some cases, home parenteral nutrition (HPN) is the only method that patients have to maintain their nutritional status. OBJECTIVE Analyze the epidemiological data of patients on home parenteral nutrition of an ambulatory of short bowel syndrome of a public tertiary referral hospital in São Paulo, Brazil. METHODS This was a retrospective study that evaluated patient files from January 1990 to April 2013. Our ambulatory takes place in the Digestive Surgery Division of University of Sao Paulo medical School. We collected data from medical records of outpatients who have used or were in current use of HPN. The statistics variables analyzed are: gender, age, underlying disease, remnant small bowel length, presence of ileocecal valve, current use of parenteral nutrition, outcomes and cause of death. Descriptive analysis with mean +- standard deviation for quantitative variables and percentages for qualitative variables. The statistical package R 3.0.2 was used to obtain the results. RESULTS A total of 30 cases were recorded: 20 (66%) males and 10 (33%) females, with a mean age of 39.9 ± 16.6 years. Seven of them, had the indication to initiate HPN because of intestinal pseudo-obstruction and 23 patients suffered intestinal resection. The most common underlying disease category that led to the short bowel syndrome was acute abdominal vascular emergencies (11, 47,8%). Three patients had less then 60cm of remnant small bowel length with ileocecal valve preserved and 20 patients had xxxxxxx no ileocecal valve. From these 20 patients, 3 (15%) had <100cm of remnant small bowel length, 12 (60%) patients 99-50cm and 5(25%) patients <50cm. During the period of the study, 10(33%) patients died, and in 80% the cause of death was infections related to the catheter. In the same period, 11 (37%) patients were able to discontinue HPN. The mean length of HPN was 26 months +- 36 (range from 2 months to 118 months). Graphic 1: Percentage distribution of causes that led to intestinal resection Graphic 2: Mean of remnant smal bowel length (centimeters) Graphic 3: Mean of HPN length (months) xxxxxxx CONCLUSION This first analysis of the epidemiological data of our patients shows that the major part of the patients were male, the most common underlying disease category that led to the short bowel syndrome was acute abdominal vascular emergencies and 37% of the patients were able to discontinue the home parenteral nutrition in the period.