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4.2 of Photosynthesis •SetOverview up Cornell Notes on pg. 61 •Topic: 5.3 Regulation of the Cell Cycle •Essential Question: 1. How do cancer cells differ from healthy cells? 5.3 Regulation of the Cell Cycle 2.1 Atoms, Ions, and Molecules 1. How do cancer cells differ from healthy cells? Key concept: Cell Cycle regulation is necessary for healthy growth 4.2 Overview of Photosynthesis Pg. 60 Cancer Circle Map Cancer Cancer Multi-Flow Map 5.3 Regulation of the Cell Cycle KEY CONCEPT Cell cycle regulation is necessary for healthy growth. 5.3 Regulation of the Cell Cycle • Please create a circle map identifying anything you know about cancer, types of cancer, treatments, causes of cancer Cancer 5.3 Regulation of the Cell Cycle WHAT I KNOW Can be deadly Some are curable Some can be prevented CAUSES Cancer TYPES Lung cancer Breast cancer Skin cancer Liver cancer leukemia Thyroid cancer Smoking drinking Chewing tobacco Sun exposure Radiation exposure 5.3 Regulation of the Cell Cycle Discussion Question… • Have you ever watched a movie in which people play with the elements of nature? These movies are usually “scary” and involve things getting “out of control”. • List a few movies where this occurs: – Tell me the name of the movie – What happens? 5.3 Regulation of the Cell Cycle “OUT OF CONTROL” 5.3 Regulation of the Cell Cycle • Growth factors are proteins that stimulate cell division. – Most mammal cells form a single layer in a culture dish and stop dividing once they touch other cells. 5.3 Regulation of the Cell Cycle • Apoptosis is programmed cell death. – a normal feature of healthy organisms – caused by a cell’s production of self-destructive enzymes – occurs in webbed fingers development of infants 5.3 Regulation of the Cell Cycle • Cancer is the common name for a class of diseases characterized by uncontrolled cell division. – Arises when regulation of the cell cycle breaks down – Continue to divide, may lead to uncontrolled growth 5.3 Regulation of the Cell Cycle • Cancer cells do not carry out necessary functions. • Cancer cells come from normal cells with damage to genes involved in cell-cycle regulation. 5.3 Regulation of the Cell Cycle • Cancer cells form disorganized clumps called tumors. – Benign tumors remain clustered and can be removed. – Malignant tumors metastasize, or break away, and can form more tumors. normal cell cancer cell bloodstream 5.3 Regulation of the Cell Cycle • Carcinogens are substances known to promote cancer. – Ex: cigarettes, formaldehyde, pesticides, smog, etc…. 5.3 Regulation of the Cell Cycle • Standard cancer treatments typically kill both cancerous and healthy cells. 5.3 Regulation of the Cell Cycle Cancer treatments Radiation therapy chemotherapy Surgery to remove the cancer 5.3 Regulation of the Cell Cycle • Please add new information to your circle map Cancer 5.3 Regulation of the Cell Cycle Homework/Classwork: Multi-Flow Map of Cancer Cancer Causes Effects, outcome