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Use of stem cells to treat skeletal muscle tissue injuries Index • • • • • • • • • • Skeletal muscle injuries What is musculoskeletal system Types of musculoskeletal disorders Musculoskeletal injuries Carpal tunnel syndrome Muscle/tendon strain Tension neck syndrome Tendonitis Ligament tear Cartilage tear Index • Prevalence in India • Current Treatment • Treatment using cord blood stem cells • Use of cord blood stem cells • Regenerative stem cell therapies • Cord blood stem cell therapies • preservation of stem cells Introduction: Skeletal muscle injuries are very common and account for more than 35% of total sports injuries and musculoskeletal traumas. Due to a lack of treatment options, new therapies are being explored using cord blood stem cells. Cord blood stem cells are derived from umbilical cord of a newborn baby! This article gives a brief idea about musculoskeletal system, types of injuries, role of cord blood stem cells, source of cord blood stem cells and more benefits of umbilical cord stem cell banking. What is musculoskeletal system? It is an organ system that gives humans the ability to move using their muscular and skeletal systems. It provides support, grip, stability and movement to the body. Types of musculoskeletal disorders and injuries: Musculoskeletal disorders are injuries and disorders that affect human’s movement due to damage in musculoskeletal system (muscles, tissues, ligaments, tendons, cartilage, nerves, discs and more). There are more than 150 types or disorders, to name the most common ones • Carpal tunnel syndrome • Muscle/tendon strain • Tension neck syndrome • Tendonitis • Ligament tear • Cartilage tear • Prevalence in India: The prevalence of work and injury related musculoskeletal disorders is as high as 15% of total population in India. Musculoskeletal pain is prevalent in people of all socio-economic backgrounds. (Reference: ncbi.nlm.nih.gov) • Current Treatment: There are mainly 3 generic injury and pain management options – physiotherapy, surgery with short term results and medication for pain management. Treatment using cord blood stem cells: There are a large amount of successful therapies developed using cord blood stem cells. Cord blood stem cells originate from umbilical cord. Umbilical cord is the cord that connects the mother and fetus. It is the richest source of stem cells. These stem cells can be used only if umbilical cord blood stem cell banking is done. To read more about cord blood stem cells and umbilical cord banking. Use of cord blood stem cells: Cord blood stem cells can replace diseased cells, inflamed cells, damaged tissues and also regenerate into new healthy cells. Regenerative stem cell therapies heal damaged cells and tissues naturally without scar formation. Cord blood stem cell therapies are patient specific and a permanent cure. If cord blood stem cells are injected in the injured area either through allogenic of autologous stem cell transplant they perform 5 functions to heal the damage. • • • • • Angiogenesis: formation and supply of new blood, to promote healing and cell formation supply growth factors which are nothing but protein molecules which divide and grow into particular tissue types. Contribution to generation of new tissues Stop cell death Make a matrix of healthy functional cells and pull in more stem cells in the injured area to generate and multiply healthy cells Considering the benefits of cord blood stem cells, every to-be parent must consider umbilical cord blood banking. Umbilical cord blood stem cell banking will ensure preservation of stem cells for 21 years and they would be readily available for the baby and family anytime. Thank You www.babycell.in Image Source: neurosciencenews.com, lghttp.41526.nexcesscdn.net, s-media-cache-ak0.pinimg.com,image.slidesharecdn.com, mpa.net.my, guardianlv.com, stemcells21.com