Transcript Midsemester Presentation 1489 kb Friday

An MR-Compatible Device for
Imaging the Lower Extremity
During Movement and Under
Load
Team Leader: Sarajane Stevens
Communicator: Arinne Lyman
BSAC: Christopher Westphal
BWIG: Eric Bader
Client: Professor Darryl Thelen
Advisor: Professor William Murphy
Overview
• Problem Statement
• Motivation
• Background
– Muscle Anatomy/Injury
– Current Devices
• Design Constraints
• Designs
–
–
–
–
Accessories
Prone
On Side
Loading System
• Future Work
• References
Problem Statement
Most current imaging techniques used to visualize knee
kinematics are static and don’t provide direct
measurements of biomechanical function. These
applications require the use of a non-magnetic device for
loading or guiding the limb through a desired, repeatable
movement. Our initial intended application is to use
Cine-PC (Phase contrast) imaging to measure in-vivo
musculotendon motion of the hamstrings muscles during
a stretch-shortening cycle. Cine-PC requires multiple
cycles of motion, necessitating that the device guide the
limb through a repeatable motion at relatively low loads.
Muscle Anatomy/Injury
• 3 separate muscles
• Pulled hamstring
-Eccentric contraction
• Scar tissue formation
• Affects muscle
performance
Motivation
• Measure velocity of
muscle fibers around
scar tissue
• Prevent re-injury
• Tailor rehabilitation
programs
Summary of Current Devices
12 different devices in literature
•Subjects lay supine/prone in device
•Between 0-90 degrees flexion
•Weight attached to pulley
•Cons
• lateral motion not restricted
• non-physiological load
• patient fatigue
• non-periodic motion
Design Constraints
•
•
•
•
•
•
Provide repeatable, harmonic motion
Same start/end points – bore size
Generate physiological load on hamstring
Simulate swing phase of running
Support thigh – limit movement
Non-metallic, non-ferrous materials
Design Components
Designs – Thigh Restraint
• Stabilizes thigh for
maximum resolution
• Prevents unwanted
movement
• Must accommodate
RF coil
Designs - Boot
• Angled for maximum
knee extension
• Restricts movement
and supports ankle
• Provides attachment
point to system
Design - Prone
• Shank moves up and down
• Must counteract weight of shank
• Greater range of motion
Design – Lateral
• Upper leg
supported by table
• Lower shank
moves back and
forth
• No effects of
gravity
• Restricts lateral
motion
k
Loading System -Spring
Loading System - Dampener
c
I
Loading System - Inertial
Inertial Systems
Future Work
•
•
•
•
•
Determine loading system
Finalize design
Obtain materials
Build prototype
Test prototype
References
1. Asakawa DS, Nayak KS, Blemker SS, Delp SL, Pauly JM, Nishimura DG, Gold GE. Real-time imaging of skeletal muscle velocity. Journal of
Magnetic Resonance Imaging. 2003; 18:734-739.
2. Asakawa DS, Pappas GP, Blemker SS, Dracce JE, Delp SL. Cine phase-contrast magnetic resonance imaging as a tool for quantification of
skeletal muscle motion. Seminars in Musculoskeletal Radiology. 2003; 7(4):287-295.
3. Asakawa DS, Blemker SS, Gold BE, Delp SL. In vivo motion of the rectus femoris muscle after tendon transfer surery. Journal of
Biomechanics. 2002; 35(8):1029-1037.
4. Asakawa DS, Pappas GP, Blemker SS, Drace JE, Delp SL. Cine phase-contrast magnetic resonance imaging as a tool for quantification of
skeletal muscle motion. Seminars in Musculoskeletal Radiology. 2003; 7(4): 287-295.
5. Barance PJ, Williams GN, Novotny JE, Buchanan TS. A method for measurement of joint kinematics of 3-D geometric models with cine
phase contrast magnetic resonance imaging data. Journal of Biomechanical engineering. 2005; 127:829-837.
6. Barrancce P, Williams G, Sheehan FT, Buchanan TS. Measurement of tibiofemoral joint motion using CINE-Phase Contrast MRI.
7. Barrancce P, Williams G, Sheehan FT, Buchanan TS. Measurement of tibiofemoral joint motion using CINE-Phase Contrast MRI.
8. Fellows RA, Hill NA, MacIntyre NJ, Harrison MM, Ellis RE, Wilson DR. Repeatability of a novel technique for in vivo measurement of threedimensional patellar tracking using magnetic resonance imaging. Journal of Magnetic Resonance Imaging. 2005; 22: 145-153.
9. Komi PV. Stretch-shortening cycle: a powerful model to study normal and fatigued muscle. Journal of Biomechanics. 2000; 33:1197-1206.
10. Neu CP, Hull ML. Toward an MRI-based method to measure non-uniform cartilate deformation: an MRI-cyclic loading apparatus system and
steady-state cyclic displacement of articular cartilage under compressive loading. Journal of Biomechanical Engineering. 2003;
125(2):180-188.
11. Pappas GP, Asakawa DS, Delp SL, Zajac FE, Drace JE. Nonuniform shortening in the biceps brachii during elbow flexion. Journal of
Applied Physiology. 2002; 92:2381-2389.
12. Patel VV, Hall K, Ries M, Lotz J, Ozhinsky E, Lindsey C, Lu Y, Majumdar S. A three-dimensional MRI analysis of knee kinematics. Journal
of Orthopedic Research. 2004; 22:283-292.
13. Patel VV, Hall K, Ries M, Lindsey C, Ozhinsky E, Lu Y, Majumdar S. Magnetic resonance imaging of patellofemoral kinematics with weightbearing. Journal of Bone and Joint Surgery. 2003; 85:2419-2424.
14. Patel VV, Hall K, Ries M, Lindsey C, Ozhinsky E, Lu Y, Majumdar S. Magnetic resonance imaging of patellofemoral kinematics with weightbearing. Journal of Bone and Joint Surgery. 2003; 85:2419-2424.
15. Rebmann AJ, Rausch T, Shibanuma N, Sheehan FT. The precision of CINE-PC and Fast-PC sequences in measuring skeletal kinematics.
Proc. Intl. Soc. Mag. Reson. Med. 2001; 9: 83.
16. Rebmann AJ, Sheehan FT. Precise 3D skeletal kinematics using fast phase contrast magnetic resonance imaging. Journal of Magnetic
Resonance Imaging. 2003; 17: 206-213.
17. Sheehan FT, Drace JE. Quantitative MR measures if three-dimensional patellar kinematics as a research and diagnostic tool. Medicine and
Science in Sports and Exercise. 1999; 31(10): 1339-??.
18. Sheehan F, Zejac FE, Drace J. Imaging musculoskeletal function using dynamic MRI. Rehabilitation R&D Center Progress Report. 1996.
19. Thelen DG, Chumanov ES, Sherry MA, Heiderscheit BC. Neuromusculoskeletal models provice insights intot he mechanisms and
rehabilitation of hamstring strains. Exercise and Sports Science Reviews. 2006; 34(3): 135-141.
20. Vedi V, Williams A, Tennant SJ, Spouse E, Hunt DM, Gedroyc WMW. Meniscal movement: an in vivo study using dynamic MRI. British
Editorial Society of Bone and Joint Surgery. 1999; 81-B(1):37-41.
Questions?