Transcript Contrast in MRI

Contrast in MRI
PD, T1, and T2
Proton Density
T1-weighted
T2-Weighted
PD, T1, T2
http://www.med.harvard.edu/AANLIB/ (Whole Brain Atlas)
Clinical History
Chronic Subdural Hematoma / Subdural Hygroma
These images are from an 76 year old man, who suffered a
severe fall 6 months before seeking medical attention.
He complained of memory loss, and had been
depressed since the death of his wife. He had a history
of alcoholism, with several hospital admissions for
gastrointestinal bleeding. Note the large fluid collection
displacing the brain. It is white on T2-weighted images,
and, of course, non-perfused on SPECT. The lateral and
third ventricles are a bit large, partly due to the effects of
age and partly to the effects of alcohol abuse. The
mammillary bodies are small in this case compared to
the normal, a finding commonly seen in alcoholics.
Anatomical
Features
T1
T2
PD (Proton
Density)
White Matter
Bright
Dark
Bright
Grey Matter
Dark
Bright
Very Bright
CSF
Very Dark
Very Bright
Grey
T1 vs. T2
http://darkwing.uoregon.edu/~schirill/t1t2.jpg
C-Spine: T1, T2
http://www.southeastiowaopenmri.com/Clinical_Photos.htm
T1, T2, T2, T2* Gradient Echo
Image Findings
Marked decrease in signal is seen in the liver on the T2- and T2*-weighted
images, with a lesser amount of decreased signal on the T1-weighted images.
Discussion
Hemochromatosis is a disorder of iron metabolism resulting in excessive iron
deposits in the liver, pancreas and skin. It is associated with diabetes, which this
patient has recently developed.
www.mritutor.org/ mriteach/9655.JPG
PD, T1, T2
The T1-weighted image shows a large spur along the inferior edge of the acromial-clavicular joint causing
impingement of the superspinatus muscle. The proton-density and especially the T2-weighted image show
abnormal increased signal in the rotator cuff tendon. An effusion is also seen in the joint space as well as in the
subdeltoid bursae.
Discussion
Tears of the rotator cuff are frequently associated with intermediate signal on T1-weighted images and
increased signal on T2-weighted images. They may be associated with fluid in the subdeltoid-subacromion
bursae, retraction of the superspinatous tendon, and atrophy of the muscle. Magic angle artifact may appear
similar to a tear on T1-weighted and proton density images. The magic angle artifact will decrease or
disappear on T2-weighted images, unlike tears.
Reference
http://www.mritutor.org/mriteach/6729.html
Guess?!?!
Fatal Stroke
The patient was a 71 year old woman with a history of ischemic
cardiomyopathy and renal insufficiency who developed the sudden onset
of left hemiplegia, hemineglect, hemianaesthesia, mutism and bilateral
ptosis. She was treated for elevated intracranial pressure, but
deteriorated and developed an enlarged right pupil and a decreased level
of arousal. She expired 5 days after admission.
http://www.med.harvard.edu/AANLIB/cases/case37/mr3/012.html
CT, T2, PD, T1
Fatal Stroke
The patient was a 71 year old woman with a history of ischemic
cardiomyopathy and renal insufficiency who developed the sudden onset
of left hemiplegia, hemineglect, hemianaesthesia, mutism and bilateral
ptosis. She was treated for elevated intracranial pressure, but
deteriorated and developed an enlarged right pupil and a decreased level
of arousal. She expired 5 days after admission.
http://www.med.harvard.edu/AANLIB/cases/case37/mr3/012.html
PD, T1, T2, CT
Fatal Stroke
The patient was a 71 year old woman with a history of ischemic
cardiomyopathy and renal insufficiency who developed the sudden onset
of left hemiplegia, hemineglect, hemianaesthesia, mutism and bilateral
ptosis. She was treated for elevated intracranial pressure, but
deteriorated and developed an enlarged right pupil and a decreased level
of arousal. She expired 5 days after admission.
http://www.med.harvard.edu/AANLIB/cases/case37/mr3/012.html