Transcript Muscular Dystrophy

Muscular Dystrophy
Evaluation of Mamsagni
Rasayana [MGR] in
55 Patients of
DMD, BMD & LGMD
Mukesh Jain, AMDS India
The Ayush Samiti Bhilai CG
Muscular Dystrophy
• Incurable Genetic disease
• The dysfunction of Vata & Dhatvagnis is the main
pathology. Muscle degeneration due to progressive
diminishing of Mamsagni along with aggravation of Vata
element.
• Symptoms & Signs: # Large calf muscles
• # Walking on the toes
• # Using the hands to rise from a sitting position, called
Gower's sign
• # Progressive muscle deterioration, starting with the
muscles nearest the hips
• # Curvature of the spine # Enlargement of the heart muscle
• # intellectual impairment # Breathing Difficulty.
Muscular Dystrophy
Mamsagat Vata Vyadhi
Treatment, Help & Monitoring
• The major goal of early treatment is to keep the
ability to walk as long as possible.
• Pawan Muktasana, Stretching exercises and using
braces at night help avoid the tightening of
tendons.
• Surgery can be used to release tight tendons.
• Mamsagni Rasayana is promising molecule. It is
an ayurvedic dietary supplement and is safe and
superior than Prednisone for long term
management of muscular dystrophies.
Ayurvedic Treatment
• Panch Karma & Rasayana treatments have
shown promising protective effects on
NMD.
• These therapies and remedies help in the
regeneration of dhatus because they are
capable to balance the Doshas and Agnis.
• TMP Swedana procedure is effective to
stabilize Vata dominant Sarcolemmal
membrane defect.
Care through Research Clinic Bhilai
• Study involving
Mamsagni
Rasayana
along with
TMP & Yogic
Support
• AMDS India
yielded mixed
results in 55 boys
of DMD, BMD &
LGMD
. Over
100 cases of Muscular dystrophies
were enrolled at Panch Karma Clinic of
Central Medical Institute, Bhilai
& treated during March 1999 & Sep 2004.
28 DMD , 19 BMD 8 LMGD boys
All the Dystrophy boys were subjected to
2 weeks Panch karma procedures
before administration of oral
Mamsagni Rasayana along with Yogic
support for 6 months.
Observation & Results:
• It was observed that degeneration of muscle
fibers were arrested after 6 weeks of
administration of Mamsagni Rasayana. This was
presumed on the basis of reduced CK level in
blood and functional improvement such as
• (i) Weight loss, (ii) Decrease in walking difficulty
and (iii) Decrease in the severity of contractures
and scoliosis. However DMD boys have shown
very slow progress.
RESULT ANALYSIS :
DMD
(BARTHEL -SANJEEVAN SCALE)
• MARKED RELIEF
42%
• MODERATE
21%
• MILD RELIEF
36.8%
RESULT ANALYSIS
60
50
40
DMD
BMD
LGMD
30
20
10
0
6 Weeks 12 Weeks 18 Weeks 24 Weeks
Average Observations
Improvement in Functional Ability
visible after 6 weeks of
Administration of MGR
Presumption : Reduced CPK level,
weight loss, Decrease in Walking
difficulty.
Decrease in the Severity of
Contractures and Scoliosis.
Average Decrement in 24 Weeks
10%
CONTRACTURE
BLOOD CK
-2.8 Kg. -2800 (IU)
WT LOSS
SEVERITY
45%
Quality of Life Improvement
60%
ENDURANCE
FUNCTIONAL
40%
SELF CONFIDENCE
90%
A Case Of DMD
PATIENT BEFORE
TREATMENT
PATIENT AFTER TREATMENT
EFFECT OF TMP IN DMD
BEFORE REATMENT
AFTER TREATMENT
Effect of Mamsagni Rasayana
BEFORE TREATMENT
AFTER TREATMENT
Functional Improvement in a DMD
BEFORE TREATMENT
AFTER 12 WEEKS
Improvement in DMD Boy
BEFORE TREATMENT
AFTER TREATMENT