Transcript French Network for Animal Health Who?

The French Network for
Animal Health
ETPGAH Mirror Groups meeting
Tuesday 23 November 2010
Fabienne Cournarie
Director of Public Affairs, SIMV
France
French Network for Animal Health
Why?
Implementation, at the national level, of the EU guidelines and
objectives defined in the ETPGAH Action Plan = « Mirror
Groups »
How?
• Initiative of the French Ministry of Agriculture, launched in
May 2007
French Network for Animal Health
Who?
• Ministry of Agriculture (and Fisheries)
• French Agency for Sanitary Safety
(ANSES)
• Animal Health Industry, united in SIMV
• National Veterinary Schools (ENV)
• National Institute of Agronomy Research
(INRA)
• Agricultural Research Centre for
International Development (CIRAD)
• Technical Veterinarians Union (SNGTV)
• Sanitary Defence Groups (farmers)
(FNGDS)
• Public Veterinary Diagnostic Laboratories
Government
Regulatoy authorities
Industry
Vet schools
Public research
organisms
Vet organisations
Farmers
Diagnostic labs
French Network for Animal Health
Who?
New members in 2010:
• AVEF : Veterinary organization for horses welfare
• AFVAC : Veterinary organization for companion animal care
• INSERM : Public research organism
• ITAB : Technical institute of organic farming
Stakeholders covering the whole range of
animal health professionals
French Network for Animal Health
Missions
EUROPE
FP-7
French
Authorities
Public research
Private research
Users:
Veterinarian
Farmers
French Network for Animal Health
Structure
Steering
Committee
4 working groups
To provide
solutions to the
immediate
needs
Emerging
diseases
Europe
Antimicrobial
resistance
Public
Private
cooperation
French Network for Animal Health
Working group 1:
“orphan drugs” availability
1. Solved Issues
Either by maintaining enough stocks in case of TU or
by succeeding in the idea of preparing a CTD
•
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Anthrax vaccine (sporadic cases): TU
Q fever : CTD in progress
tuberculin for ID tests
Local anaesthetics for ruminants: proposal made to CVMP
Oral sedation for ruminants : CTD?
Dexamethasone ovine
Ruminant cryptosporidosis : CTD in progress
Very positive output. Having all actors (regulatory
authorities, manufacturers, veterinarians and
farmers) around the same table has definitely helped
to define rapid and pragmatic solutions.
French Network for Animal Health
Working group 1:
“orphan drugs” availability
2. Issues which require a European involvement
• Paratuberculosis vaccine: an attenuated form is required
• Histomonosis: no treatment available
• Products for bee disease treatment
To evaluated needs at the level of Europe
To federate expertise and means
French Network for Animal Health
Working group 2:
emerging disease
1.
Concerted list of immediate (“operational”)
research needs:
blue tongue is a priority
• Epidemiology, diagnostic tools, molecular typing, BTV status in
wildlife…
• Consequences on reproduction performances, on husbandry
practices
• Economical impacts (direct and indirect)
• Vector biology and control measures
• Vaccines (safety and efficacy in “minor species”)
2.
Longer-term research: pathogenesis, immunology
French Network for Animal Health
Working group 2:
emerging disease
RFSA achievements on blue tongue:
•
Government funded research programs (total of 1,5 M€ for Short
Term perspectives) : 10 projects were funded
•
Meeting on RFSA initiative for the review of the on going research
projects on BTV (March 18th 2010 ) : among them 4 priorities were
selected
Success because achieved in less
than 2 years
French Network for Animal Health
Working Group 3: Europe
1. Links with EMIDA – ERA NET, Discontools
First EMIDA common calls:

77 pre-proposals were received, 45 were shortlisted,
only 12 were identified for funding, 8 projects have
french partners

projects with french partners:
“vector borne disease” : 2
“major infectious diseases affecting production”: 5
“aquaculture”: 1
French Network for Animal Health
Working Group 3: Europe
2. FP7

Analyse the European project calls : analyse the
reflection paper of FP7 projects calls and share the
information with its partners

Propose to the European commission : based on
the FP7 projects calls and/or on RFSA coordinated topic
priorities , propose projects to the European
commission
French Network for Animal Health
Working Group 3: Europe
List of topics proposed to the FP7 theme 2 Program committee by
the french ETPGAH mirror group in January 2010
 Main line 1, Animal health and non food-borne zoonoses
Topics:
• Ruminant pathogenic mycoplasmas: from genomics to the development of
new control strategies
• The assessment of the within-herd dynamics of endemic pathogens in pigs
The priority of these topics has been confirmed in september 2010
French Network for Animal Health
Working Group 3: Europe
List of topics proposed to the FP7 theme 2 Program committee by
the french ETPGAH mirror group in January 2010 (continue)
 Main line 2, Food borne zoonoses :
Topics:
• Knowledge of Trichinella nurse cell
• Trichinella control
 Main line 3.1 Animal health and non-food borne zoonoses:
Topic:
• Alternative/complementary medication in organic/low-input livestock
systems
French Network for Animal Health
Working Group 3: Europe
New topics proposed to the FP7 theme 2 Program committee by the
french ETPGAH mirror group in September 2010
Main line: 3.1: Animal health and non food-borne zoonoses
Q Fever
• “Resistant forms of C. burnetii: characterisation, role in
maintenance and transmission of the disease, exploration of
prophylactic strategies”
• “Study of genomic plasticity and biodiversity of C. burnetii
strains populations and relationships to pathoadaptation and
epidemiological factors”
Bee diseases
• “Development and Harmonization of tests in diagnosis and bee
research (HARMONY)”
French Network for Animal Health
Working Group 3: Europe
2. FP7 (continue)
Main line 1.2: 'Omics technologies', systems biology and other basic
sciences in farm animals.
Gaps:
 Bioinformatics, systems biology, immunology
 Epigenetics
 Host-pathogen interaction, identification of protective antigens in
complex pathogens
 Cutting edge vaccinology platform
Topic: Integrating systems biology outputs to generate cutting
edge vaccines and predictive protection in farm animals
French Network for Animal Health
Working Group 3: Europe
2. FP7 (continue)
Main line 3.2: Food-borne zoonoses, antimicrobial resistance.
Gaps:
 antimicrobial resistance
Topic: Management of increased antimicrobial resistance in animal
populations
French Network for Animal Health
Group 4: Private-public
cooperation
1. Identification of subjects of interest for possible private-public
cooperation: done
• Antimicrobial resistance
2. To define the rules for a productive PPP cooperation
•
(resolution of legal aspects, technical issues…): next step
3. Links with ARIIS :
• Brings together all industries involved in health (human,animals…)
• Calls for projects from the French government to create
institute to enhance the translational research (hospital,
university, biotech/pharma companies)
• Infectious disease institute was proposed including zoonoses
French Network for Animal Health
Antimicrobial resistance: 5 priorities
 Research on epidemiology and physiopathology of bacterial
disease in animals
 Alternative to antibiotics
 How pathogenic are transmitted from animals to human? Contact,
alimentation, environment
 Economics analysis
 Which strategies for the treatment of animals with antibiotics?
A national committe for the cautious use of antibiotics will be
launched in January 2011
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