Transcript RUG - Template basic ENG

Since 1614
400 years of
Passion & Performance
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Dutch Universities: Research with Focus on Top
Sectors. Cooperation with Russia in Field of
Life-Science & Health
Sibrandes Poppema
Scientific output 2002-2012
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USA
PEOPLES REP CHINA
GERMANY
JAPAN
ENGLAND
FRANCE
CANADA
ITALY
SPAIN
AUSTRALIA
INDIA
SOUTH KOREA
NETHERLANDS
RUSSIA
3,250,380
1,022,597
845,448
803,857
747,867
603,328
493,736
470,648
382,658
338,947
334,660
325,403
276,918
275,325
51,546,027
6,653,426
11,340,845
8,390,864
11,306,492
7,556,253
6,588,762
5,689,120
4,079,695
4,098,351
2,059,832
2,385,604
4,376,263
1,371,065
15.86
6.51
13.41
10.44
15.12
12.52
13.34
12.09
10.66
12.09
6.15
7.33
15.80
4.98
University rankings
3
Nature
Publishing Index: 85
Scientist Best Places to
Work in Academia: 24
New York Times
Employability: 81
Publications In Nature or Science
University-Business cooperation
(Netherlands)
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 Public-Private Partnerships in top-institutes
(investigator driven, precompetitive with industry)
 Intermediate (industry driven, with investigators)
 New: top-sector policy
(9 areas, government policy)
.
Horticulture
Agri & Food
Water
Life sciences & Health
Chemistry
High tech
Energy
Logistics
Creative industry
Head offices
Topsector Life Sciences
Healthy
Ageing
Source: Topsectorplan Life Sciences and Health
University Medical Center
1797
1797
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Zernike Science Campus
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Relevance to Society
Multidisciplinary, University, Industry,
Governments & Public Participation
1. Healthy ageing (HANNN)
• Biobank & Cohort study Lifelines (165,000 participants)
• European Research Institute on the Biology of Ageing ERIBA
2. Energy (Energy Valley)
• Energy Academy Europe EAE
• Energy Delta Institute EDI
• Groningen Centre of Energy Law
Energy Academy Europe
3. Sustainable Society
ENTRANCE: multitesting facility
Healthy Ageing:
LifeLines
www.lifelines.nl
Relative contributions of genetics and life style
to health and disease
LifeLines is a prospective cohort study and Biobank that
will follow 165,000 participants in a 3-generation design
for at least 30 years. The focus is on multifactorial, agerelated disorders.
Funding: ~120 Million Euro
September 2012:
100.000th participant
Healthy Ageing:
LifeLines
LifeLines cohort dimensions
father
www.lifelines.nl
Aselect: 45.000
Index persons
(25-50 years)
Children: 35.000
mother
child
Parents alive:
55.000
child
child
partner’s
father
partner
partner’s
mother
Partner: 30.000
Total number of
participants:
165.000
European Research Institute
on the Biology of Ageing ERIBA
Fundamental questions on the biological causes of stem cell ageing
Healthy Ageing
European Research Institute on the Biology of Ageing
Dr. Peter Lansdorp
Scientific Director
Team Leader: Laboratory of Genetic
Instability, Ageing and Cancer
ERC advanced grant 2011
Dr. Ellen Nollen
Team Leader: Laboratory of Molecular
Neurobiology of Ageing
ERC starting grant 2011
Dr. Gerald de Haan
Dr. Victor Guryev
Scientific Co-Director
Team Leader: Laboratory of Ageing
Biology and Stem Cells
Team Leader: Laboratory of Genome
Structure and Ageing
Dr. Michael Chang
Dr. Floris Foijer
Team Leader: Laboratory of
Telomeres and Genome Integrity
Team Leader: Laboratory of Genomic
Instability in Development and Disease
Dr. Eugene Berezikov
Dr. Liesbeth Veenhoff
Team Leader: Laboratory of Stem
Cell Regulation and Mechanisms
of Regeneration
ERC starting grant 2012
Team Leader: Laboratory of Cellular
Biochemistry: Role of nuclear transport in
cellular ageing
Dr. Christian Riedel
Team Leader: Laboratory of Molecular
Mechanisms in Lifespan Regulation.
International team, prestigious European ERC grants
Alliance for Healthy Ageing
with Mayo Clinics
Clearance of p16Ink4a-positive senescent cells
delays ageing-associated disorders
Darren J. Baker, Tobias Wijshake, Tamar
Tchkonia, Nathan K. LeBrasseur, Bennett G.
Childs, Bart van de Sluis, James L.
Kirkland & Jan M. Van Deursen
Nature 479, 232–236 (10 November
2011)
Prevents ageing: kyphosis, cataract etc
According to Science
one of the top 10 scientific
discoveries of 2011
Skolkovo Tech
Research Investment Strategy
Skolkovo Institute of Science and Technology 2012
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Skolkovo Tech Strategy – BioMedicine (1)
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Computational and systems biology – profoundly different
approaches to study biological systems, including complex data, in
order to support both basic, as well as applied research involving
discovery of new drugs and drug targets [high priority]
Immunology and infectious disease - in terms of diseases caused
by multi-drug resistant bacteria and viral pandemics, the role of
microbiome in human health, and organized response to and
treatment of disease [high priority, center in negotiation]
Gene- and nano-medicine - impacting the understanding of
disease, therapeutics and drug delivery [high priority, center in
negotiation]
Regenerative medicine - stem cell research as well
as tissue and organ fabrication [high priority, center in
negotiation with ERIBA, University of Groningen]
Hey Charles,
Where are
you going?
To the University of
Groningen, always good to
get some additional schooling
THANK YOU
FOR YOUR
ATTENTION
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