Transcript Report on the 2007 Annual Survey

Report of the 2007
Annual Survey
AATB-accredited Tissue Banks in
Canada
When referencing information or data from this presentation, use the
following citation: 2007 American Association of Tissue Banks (AATB)
Annual Survey of Accredited Tissue Banks in Canada. McLean, VA:
AATB, 2010.
Managed by © In-Touch Survey Systems, Inc.
7 Survey Participants
•
All are Tissue Banks in Canada accredited by AATB
o
All of them recover, process, store and distribute tissue
o
5 Tissue Banks were inspected by agencies in 2007
 3 AATB
 4 ISO
 1 CAP
 1 Other (identity not specified)
28.6%
Inspected
Not Inspected
71.4%
Was your tissue bank inspected in 2007?
Yes = 5 (71.4%)
Inspected by Whom
AATB
ISO
CAP
5
4
3
2
1
0
# of Tissue Banks
Another Agency
Recovery
(includes referral, screening, consent, &/or recovery)
Recovery
•
How many tissue donors did your Tissue Bank recover for
transplantation? Total = 795
o
Deceased = 50.3%
 How many had an autopsy performed? 35%
o
•
•
Living = 49.7%
How many tissue donors were also organ donors? 28.8%
How many tissue donors were also ocular donors? 33.8%
Recovery - Deceased Donors
% of Tissue Banks
that Recover That
Tissue Type
Tissue Type*
# of Donors
# of Tissue
Banks
Musculoskeletal
(bone, cartilage , OA)
142
6
86
Soft Tissue
(fascia, ligaments, tendons,
pericardium, dura, nerves)
156
7
100
Skin
(thin, thick, full thickness)
160
5
71
Cardiac
(heart for valves, thoracic
aorta)
203
7
100
Vascular
(veins, arteries)
0
0
0
* These definitions are used throughout the Survey
Sites of Recovery - Deceased Donors
Site
%
Heath Care Facility Operating Room
75
Dedicated Tissue Recovery Suite
(own facility)
25
Hospital Morgue; Funeral Home; Other; or,
Medical Examiner Office (Dedicated Room, or
Open Autopsy Room)
0
“Consent” - All Donation
Associated Activity
Total
# of Tissue Banks
Responding
Approaches
1,026
3
Obtained
1,018
4
1st P/Donor Designation/Registry
243
1
NOK or Other Consenting Person
464
3
Denied
239
4
Unsuccessful - NOK Unavailable
6
3
Consent Obtained, No Recovery
291
4
Only a subset of the 7 Tissue Banks answered these questions.
“Consent” - All Donation
Successful Consents Obtained by:
%
Tissue Bank Personnel
56
Hospital Personnel
27
OPO Personnel
16
Other
1
Ineligible During Screening
(Prior to going on site for recovery)
Prevalence
Reason
%
1
Medical Hx
42.7
2
Other
(no COD, coroner refusal, consent,
pathologist refusal, no referral)
19.9
3
Time Restrictions
10.9
4
Age
8.1
5
Behavioral Risk Hx
7.3
6
Infectious Disease Testing
6.3
7
Plasma Dilution
3.4
8
Trauma
1.5
Determined Ineligible at Site of
Recovery
Prevalence
Reason
%
1
Chart findings
38
2
Physical findings
28
3
Logistics
(e.g., insufficient body cooling, time
expired, body no longer available, etc.)
25
Determined Ineligible After
Recovery
Prevalence
Reason
%
1
Medical Hx
47
2
Pre-processing cultures
21
3
Infectious disease testing
21
Processing
Processing
• # of Tissue Banks = 7
o
Process bone = 6
o
Process soft tissue = 6
o
Process skin = 4
o
Process cardiac and/or vascular = 4
o
Process tissue from Living Donors = 4 ?
• Total donors processed = 665
• Average graft yield per donor = 21
Processing
• # of Musculoskeletal Donors = 233
o
Bone = 295
o
Cartilage = 1
o
Osteoarticular (fresh) = 5
Processing
• # of Soft Tissue Donors = 174
o
Tendons = 138
o
Ligaments = 24
o
Fascia = 129
o
Pericardium = 5
Processing
•
# of Cardiac and/or Vascular Donors = 170
o
Heart Valves = 146
o
Non-valved conduits = 44
o
Artery = 1
Processing
•
# of Skin Donors = 146
o
Thin = 144
o
Thick = 2
Use of Radiation
•
•
•
No Tissue Banks treated tissues with radiation prior to
processing (non-terminal irradiation).
1 Tissue Bank treated tissues with Gamma radiation
(above 2.5 Mrads) as a final treatment.
Musculoskeletal and soft tissue grafts were primarily
treated with antibiotics during processing.
Infectious Disease Testing
Infectious Disease Testing
Test
# tested
% RR
% Confirmed
Positive*
HBsAg
846
0.83
42.86
HBcAb (total)
849
2.24
HBV NAT
72
2.78
HCV Ab
849
0.82
HCV NAT
397
0.50
HIV 1/2 Ab
849
0.24
HIV-1 NAT
404
0.74
HIV-1/HCV NAT
451
1.11
HTLV I/II Ab
845
0.24
50.00
Syphilis
845
0.59
0
WNV NAT
462
0.43
CMV Ab
29
37.93
57.14
The most frequently relied
upon test to confirm a
repeat-reactive syphilis
screening test was FTAABS, which was used by 4
Tissue Banks.
0
* Not all tissue banks
perform confirmatory
testing. Of those who
did, these %s are from
their experience.
Distribution
Distribution
• All 7 Tissue Banks distributed tissue from deceased
donors:
Soft tissue = 7
MS = 6
Cardiac = 4
Skin = 4
• 5 Tissue Banks distributed tissue from living donors.
99% of tissues were distributed directly to
Hospitals/Medical Facilities.
Distribution
(tissue from deceased donations)
Graft type
# of grafts reported
Musculoskeletal
3,051
Skin
1,141 (pkgs)
Soft Tissue
940
Cardiac
187
Vascular
0
Distribution
(tissue from living donors)
•
Total grafts distributed = 270
o
Surgical/Allogeneic Bone = 176
o
Amniotic Membrane = 58
o
Other Tissues = 28
o
Autologous bone = 8
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