Transcript My Course - Biology Scholars

BIOL2450 APPLIED MICROBIOLOGY
Course Context: Allied health course for nursing students (non-traditional, diverse, low-income,
women, and EFL). Four credit course with lab.
Learning
Objective
(1) Define
terminology used
to describe
microbe-host
interactions
Taxonomy
Remember
(2) Synthesize
Understand,
major concepts to Apply,
solve case studies Analyze,
Evaluate, and
Create
Learning Activities
Formative
Assessment
Summative
Assessment
Assigned textbook
readings with list of
terms to know and
crossword activity
Online quiz.
Exam
Written assignment
that process
information gathering
and decision making to
solve case study.
Peer review classmate
case study one
Draft of case
study one.
Flow Chart.
Four case studies
Learning Activities
(1) Assigned textbook readings with list of terms to know
and worksheets/crossword activity (pre-class)
(2) Case Studies
– Part 1: Extrapolate key information from case studies
– Part 2: Conduct research and information gathering to analyze case studies
– Part 3: Assemble information in case studies and from research to determine
the etiological agent
– Part 4: Construct a paper with correct citations and defend choice of
microbe
– Part 5: Peer review case study 1 with comments using grading rubric
• Written assignment that process information gathering and decision making to
solve case study. Flow Chart. (Assigned in class with examples and students
conduct outside of class time)
• Peer review classmate case study one (Demonstrated with guidelines in class
and students are placed into groups of 4 on D2L and given 4 blinded case study
to assess as a group)
Formative Assessments
(1) Online quiz
Matching: Match the following terms to its definition.
__ pathology
a) development of disease
__ etiology
b) results in both organisms benefiting
__ pathogenesis
c) study of disease
__ parasitism
d) study of cause of disease
__ commensual
e) results in one benefiting and the other being harmed
__ mutualism
f) results in one benefiting and the other is unaffected
Multiple Choice: AIDS is one of the top three infectious
disease worldwide. What would AIDS be classified as?
a) Endemic
b) Epidemic
c) Pandemic
d) Sporadic
(2) Draft of Case Study 1
After student groups have reviewed case study one, I grade the quality of review as well as add my
own comments. Denote (+) useful comments and (-) not relevant. Students will have a chance to
correct case study one and apply those corrections to the remaining three case studies
Summative Assessments
(1)Exam
Fill-in-the-blank: The majority of normal flora in
humans are considered to be ____ (type of symbiosis).
Short Answer: A 27-year old woman was seen at the
clinic for painful urination. She was diagnosed with a
UTI caused by endogenous E. coli. Explain how and
why this may have occurred.
(2) Case Study 1, 2, 3, and 4 (Rubic)
Timeline
Unit One: Microbial structure and function,
metabolism, growth, and genetics (Fall 2012)
Unit Two: Eukaryotic Microorganisms (Fungus,
Protozoa, and Viruses) (Winter 2013)
Unit Three: Symbiosis, Principles, and
Pathogenicity (Summer 2012)
Unit Four: Immunity and Antimicrobial Agents
(Summer 2013)
Unit Five: Microbial Diseases (Fall 2013)
Case study Assignment
DUE DATE: July 27
Case Study Guidelines:
•Case studies must be typed with Times New Roman, 1” margins, and
double-spaced.
•Include a cover sheet with your name and date.
•This is a writing assignment; answers must be written using complete
sentences, correct grammar, and spelling. You will have to say clearly how
and why you came to this conclusion. If you are not sure about what the
answer should be, you should explain why you couldn’t come to a
conclusion
•Write the names of the microorganisms in correct scientific notation. The
full name of a microorganism must be used once before the abbreviated
version can be used.
•There is a min. requirement of 1 page and max. of 3 pages per case study.
•Please keep in mind that the genus name of an organism is not the same as
the full scientific name of an organism. The name of the disease/infection
is often different from the name of the microorganism.
•Each student must have distinctly separate answers (no paraphrasing!).
Students that have similar typed answers will receive no credit and will not
be able to resubmit case study.
•Use proper citation (in text and reference page) and be consistent with
your citation method
•Case studies need to be submitted in paper by July 27 at the beginning of
class (if you are late to class, your case studies will be considered late) –
Students may submit case studies in advance by email/paper.
For each case study, answer the following questions:
1. What is the etiological agent? Describe the morphology (shape,
arrangement, gram reaction) and cultural properties (O2 requirement,
biochemical requirements, motility, etc…) of this etiological agent.
2. Explain the spread of infection (reservoir & transmission) and
pathogenicity (3 virulent factors) of this agent relevant to this case study.
3. Describe the diagnoses and treatment (name of Rx, what it targets, why
does it work against this microbe) for this agent relevant to this case study.
Case #1
Description: An 18-year-old male is admitted to the
hospital with massive tissue destruction along her right
leg. The skin is a violet color and large fluid-filled
blisters are present. The patient has a fever, a rapid heart
rate, low blood pressure, and seems confused. Once the
area appeared to have become infected, the infection
spread very rapidly.
Lab diagnosis:
FLOW CHART
SICK PT.
GATHER INFORMATION
What information is CRITICAL?
•Patient History
•Signs & Symptoms
•Lab Diagnosis
•Patient History:
Location/Region, Mode of
transmission, and
Susceptibility.
•Signs & Symptoms:
Pathogenicity/Virulence factor
•Lab Diagnosis: Gram stain
(Shape, Arrangment, and Cell
wall type), Biochemical tests
(Growth requirements &
Metabolism), and so on
**Identify possible suspects **
CONDUCT RESEARCH
ASSEMBLE & CONSTRUCT