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X-Ray Medical Imaging Physics –
IB Objectives
I.2.1
Define the terms attenuation coefficient and
half-value thickness.
I.2.2
Derive the relation between attenuation
coefficient and half-value thickness
I.2.3
Solve problems using the equation I = I0e-x
I.2.4
Describe X-ray detection, recording, and
display techniques
I.2.5
Explain standard X-ray imaging techniques
used in medicine
I.2.6
Outline the principles of computed
tomography (CT)
3/06/2009
1
IB Physics HL 2
X-Ray Production
Anode **Spinning**
(Tungsten)
(Why?)
Vacuum
chamber
...
High voltage
Hot filament
cathode
X-rays
Electrons
Filament voltage
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IB Physics HL 2
X-Ray Interaction with Matter
and Attenuation
X-rays interact with matter in four ways
Photoelectric effect (photon in – electron out)
Coherent scattering off atom as a whole (photon in
– photon out)
Compton scattering off electron (photon in –
electron + photon out)
Pair production (photon in – electron + positron
out) (E > 1 MeV)
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IB Physics HL 2
X-Ray Interaction with Matter
and Attenuation
Photoelectric effect
Orbital electron
knocked out of
atomic orbit
creating ion
Incoming photon
scatters off
orbital electron
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IB Physics HL 2
X-Ray Interaction with Matter
and Attenuation
Coherent scattering / Rayleigh scattering
Atom not ionized nor excited
Outgoing photon
scatters off
atom as a whole
Incoming photon
scatters off
atom as a whole
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IB Physics HL 2
X-Ray Interaction with Matter
and Attenuation
Incoherent scattering / Compton scattering
Electron scattered
out of atom
Incoming photon
scatters off
single electron
(as if electron were
free)
Outgoing photon
after scattering off
electron
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IB Physics HL 2
X-Ray Interaction with Matter
and Attenuation
Pair production
+ Enough energy in initial beam to create e e pair
Nucleus interacts
with incoming
photon
eElectron-positron
pair created from
incoming photon
and nuclear interaction
Incoming photon
scatters off nucleus
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e+
7
IB Physics HL 2
X-Ray Interaction with Matter
and Attenuation
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8
For carbon
(~people)
below 12 keV,
increasing
energy
decreases
interaction
Interaction
mainly from
photoelectric
effect
Bones (heavier
nuclei)
attenuate Xrays more than
soft tissue
(carbon)
IB Physics HL 2
X-Ray Attenuation Coefficient
Similar to radiation half-lives and decay coefficients
Decrease in intensity (W/m2) is proportional to initial
intensity:
dI
I
dx
With solution: I = I0e-x
is the linear attenuation coefficient (m-1)
does depend on energy
3/06/2009
This gives the intensity at depth x meters
9
IB Physics HL 2
X-Ray Half-Value Thickness
Similar to the radioactive decay half-life, we can
define a half-value thickness at which the beam
drops to one-half its initial intensity
-x1/2
I0/2 = I0e
-x1/2
or 0.5 = e
or ln(0.5) = -x1/2
or = ln(2) / x1/2 (just like radioactive decay)
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IB Physics HL 2
X-Ray Choice of Wavelength
Choice of wavelength depends on what is being
imaged
Bone
Soft tissue
Also want to minimize absorbed energy
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IB Physics HL 2
X-Ray Attenuation Sample Problem
The attenuation coefficient for an X-ray of a specific
wavelength through muscle is 0.045 cm-1
What is the half-value thickness?
The half-value thickness of bone, for the same X-ray,
is 150 times smaller
What is its attenuation coefficient?
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In which of these materials does the X-ray
intensity drop off more quickly?
12
IB Physics HL 2
X-Ray Attenuation Sample Problem
(Cont’d)
If the initial X-ray intensity is 2.00 W/m2, what is its
intensity after traveling through 13.0 cm of muscle?
How much is absorbed by the muscle?
What is the intensity of the X-ray after traveling
through 3.47 cm of bone?
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IB Physics HL 2
X-Ray Beam Techniques
Improve penetrating quality of beam by absorbing
out low-energy X-rays
With large attenuation coefficients, X-rays get
absorbed easily by soft tissue
Use ~1 mm to 1 cm
of Al
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IB Physics HL 2
X-Ray Beam Techniques
Tube voltage
Increasing tube voltage increases penetrating
power of X-rays
Bremsstrahlung
K, L
spectra
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IB Physics HL 2
X-Ray Beam Techniques
Beam current
Increasing beam current increases intensity of Xrays
Does not change
penetrating power
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IB Physics HL 2
X-Ray Beam Techniques
Target material
Changing target material changes characteristic K,
L lines
Bremsstrahlung
spectrum stays
the same (more or
less)
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IB Physics HL 2
X-Ray Imaging Techniques
Putting a lead grid in front of imaging material will
improve the sharpness of the image
Scattered X-rays are
absorbed by grid
before getting to
film
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IB Physics HL 2
X-Ray Imaging Techniques
Direct image
Bone (white)
Higher energy X-ray
Soft tissue (gray)
Lower energy X-ray
Gaps – air (black)
Contrast medium
Opaque material outlines soft tissue
Barium, bismuth (intestines)
Iodine (blood)
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IB Physics HL 2
X-Ray – Coronary Arteries
3/06/2009
From: http://www.ajronline.org/cgi/content-nw/full/179/4/911/FIG8
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IB Physics HL 2
X-Ray Detection, Recording, and Display
Detection
Film, image-enhanced film, digital computer-read
screens and detectors
Recording
Film, digital film, computer memory
Display
Film, computer display, television (real-time)
display (~fluoroscopy)
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IB Physics HL 2
X-Ray Detection, Recording, and Display
Film
Person placed between X-ray tube and film
Film is detection, recording, and display
mechanism all in one
X-ray
tube
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X-ray
sensitive
film
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IB Physics HL 2
X-Ray Detection, Recording, and Display
Enhanced film (basically all modern X-rays)
Person placed between X-ray tube and film
Film is placed in cassette with X-ray sensitive
phosphors
Provides better image
Film as recording and display device
X-ray
tube
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X-ray
film cassette
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IB Physics HL 2
X-Ray Detection, Recording, and Display
Enhanced film cassette
Intensifying screens contain X-ray sensitive
phosphors that create light when struck with Xrays
Film displays X-rays detected by film and screen
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IB Physics HL 2
X-Ray Detection, Recording, and Display
Digital Radiology
Instead of normal film, X-rays detected by a plate
sensitive to X-rays
Plate is “read” by laser
Stored in computer memory
Computer display
X-ray
tube
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Digital
scanning
process
X-ray
sensitive plate
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IB Physics HL 2
X-Ray Detection, Recording, and Display
Computer Radiology
Instead of film, X-rays detected by a computerreadable screen
Computer reads screen, and stores image in
memory
Computer display
X-ray
tube
Computer-readable
X-ray phosphor screen
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IB Physics HL 2
X-Ray Detection, Recording, and Display
Real-Time Displays
Observe operation of heart, intestines, throat, etc.
Instead of film, X-rays detected by phosphors on
screen
Television camera observes phosphor screen
Display real-time image on television screen
X-ray
tube
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X-ray sensitive
phosphor screen
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IB Physics HL 2
X-Ray Medical Imaging –
Fundamental Ideas
What are they?
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IB Physics HL 2
Drawbacks of Normal X-Ray Scans
X-rays show only one view of body
Shadow of everything between X-ray tube and film
Difficult to interpret soft-tissue images
-> Idea: take X-ray scans in multiple directions
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IB Physics HL 2
Idea of Multiple Scan Directions
Imagine taking X-ray image of 2 x 2 square
Take image in horizontal direction
A
C
4
5
B
D
X-rays
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4
5
X-ray
intensities
10
Film
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IB Physics HL 2
Idea of Multiple Scan Directions
Imagine taking X-ray image of 2 x 2 square
Take second image in vertical direction
X-rays
A
C
Film
7
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4
5
B
D
11
31
4
5
8
10
X-ray intensities
IB Physics HL 2
Idea of Multiple Scan Directions
Imagine taking X-ray image of 2 x 2 square
Use both intensities to determine relative X-ray
absorption
Show relative absorption with different shading
A
C
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3
4
B
D
5
6
8
10
X-ray intensities
11
7
This is the principle of Computed Tomography (CT)
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IB Physics HL 2
Computed Tomography (CT) Scan
Schematic
Use more then just 2 x 2 resolution
Typical: 256 x 256
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IB Physics HL 2
Computed Tomography (CT) Scanners
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IB Physics HL 2
Computed Tomography Scanner
3/06/2009 From http://en.wikipedia.org/wiki/Computed_Axial_Tomography
35
IB Physics HL 2
Computed Tomography Scanner Internals
3/06/2009 From http://en.wikipedia.org/wiki/Computed_Axial_Tomography
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IB Physics HL 2
Computed Tomography – 2D to 3D
X-ray imaging system can move along the body
CT scans in cross-section
Can build up 3D model of body
Instead of pixels (picture elements): voxels
(volume elements)
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IB Physics HL 2
Computed Tomography – Usage
Brain scans
Bleeding
Stroke
Tumor
Other organs (soft tissue)
Heart
Kidneys
Etc
Applications
Tumors
Trauma
Structure
3/06/2009 From http://en.wikipedia.org/wiki/Computed_Axial_Tomography
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IB Physics HL 2
Computed Tomography – Risk Balancing
CAT scans and X-rays use ionizing radiation
Ionizing radiation is damaging to tissue
Normal X-rays give some multiples of background
radiation dosage
CAT scans give significantly more than normal X-rays
Balance help to patient from scan vs risk of damage
(cancer) from X-rays
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IB Physics HL 2
Computed Tomography –
Fundamental Ideas
What are they?
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IB Physics HL 2