Transcript Chapter 13

QOD
What are the overall functions of the
cardiovascular system? What
structures comprise the system?
Chapter 13
Cardiovascular System
I. Introduction
 Structures
– Heart
– Arteries
 Arterioles
– Capillaries
– Veins
 Venules
 Circuits
– Pulmonary circuit
– Systemic Circuit
– Coronary Circuit
13.2: Structure of the Heart
 Coverings
– Visceral pericardium
– Parietal pericardium
– Pericardial cavity – serous fluid
 Wall
of the heart
– Epicardium
– Myocardium
– Endocardium
 Purkinje
fibers
QOD
How is the heart’s structure
related to it’s function?
Heart chambers and valves
 Atria
(Atrium)
 Ventricles
 Septum
 Valves
– Tricuspid
– Bicuspid (Mitral)
– Aortic
– Pulmonary
– Chordae tendinae
– Papillary muscles
Blood Vessels to and from Heart
 Superior
and Inferior Vena cavae
 Cardiac veins
– Coronary sinus
 Pulmonary
arteries
 Pulmonary veins
 Aorta
 Coronary arteries
Pathway of Blood
QOD
How does the heart make sure to
pump rhythmically and as a unit?
13.3 Heart Actions
The Cardiac Cycle
 The
Heartbeat
– Atrial systole and ventricular diastole
– Atrial diastole and ventricular systole
– A-V valves open/close
 Due
to changes in pressure
Cardiac Cycle
 Heart
sounds
– “Lubb” – ventricular contraction
– “Dupp” – ventricular relaxation
 Cardiac
Muscle Fibers
– Fibers connect in branching system
– Functional syncytium
 In
atrial walls
 In ventricular walls
Cardiac Conduction System
 S-A
node
– Located in right atrium
– Self-initiate impulses that stimulate
cardiac muscle fibers to contract
– Rhythmic - Pacemaker
 A-V
node
– Located in interatrial septum (inferior)
– Impulse is delayed
– A-V bundle  Purkinje fibers cardiac
muscle fibers
Fig. 13.11
Fig. 13.12
Electrocardiogram
 Waves
of ECG
– P wave
– QRS complex
– T wave
 Uses:
– Assessment of heart’s conduction of
impulses
– P-Q interval
Fig. 13.14a
Regulation of Cardiac Cycle
 Medulla
oblongata
 Parasympathetic nerve fibers
 Sympathetic nerve fibers
 Hypothalamus
 Temperature change
 Ions
– Potassium ions

Hyperkalemia/Hypokalemia
– Calcium ions
 Hypercalcemia/Hypocalcemia
Autonomic nerve impulses
Slide number: 1
Carotid
sinus
Cerebrum
(coronal
section)
Sensory
fibers
Carotid
baroreceptors
Common
carotid artery
Hypothalamus
Aorta
Medulla
(transverse
section)
Cardiac
center
Aortic
baroreceptors
Parasympathetic
vagus nerve
S-A node
A-V node
Spinal cord
(transverse sections)
Sympathetic
nerve
Sympathetic trunk
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
QOD
What is atherosclerosis?
Causes? Signs/symptoms?
Treatments?
13.4 Blood Vessels
 Arteries
– Strong, elastic, under high pressure
– 3 layers
 Tunica
interna
 Tunica media
 Tunica externa
 Arterioles
– Smaller
– Get thinner as they get closer to…
Capillaries
 Gas/nutrient
exhchange
– Openings
– Semi-permeable
– Concentration gradient
– Filtration and hydrostatic pressure
– Osmotic pressure
 Smooth
muscle – regulates blood
distribution
Water and other substances leave capillaries because of a net outward
filtration pressure
Slide number: 2
Tissue
cells
Blood
flow from
arteriole
Lymphatic
capillary
Capillary
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Water and other substances leave capillaries because of a net outward
filtration pressure
Slide number: 3
Inward force
of osmotic
pressure
28 mm Hg
Blood
flow from
arteriole
Tissue
cells
Lymphatic
capillary
Net outward pressure
13.3 mm Hg
Outward force,
including hydrostatic
pressure 41.3 mm Hg
Capillary
Net force at arteriolar end
Outward force, including
hydrostatic pressure
= 41.3 mm Hg
Inward force of osmotic
pressure
= 28 mm Hg
Net outward pressure
= 13.3 mm Hg
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Water and other substances leave capillaries because of a net outward
filtration pressure
Slide number: 4
Inward force
of osmotic
pressure
28 mm Hg
Blood
flow from
arteriole
Tissue
cells
Lymphatic
capillary
Inward force of
osmotic pressure
28 mm Hg
Net outward pressure
Outward force, including
13.3 mm Hg
hydrostatic pressure
Outward force,
21.3 mm Hg
including hydrostatic
Capillary
pressure 41.3 mm Hg
Net inward
pressure
6.7 mm Hg
Net force at arteriolar end
Net force at venular end
Outward force, including
hydrostatic pressure
= 41.3 mm Hg
Outward force, including
hydrostatic pressure
= 21.3 mm Hg
Inward force of osmotic
pressure
= 28 mm Hg
Inward force of osmotic
pressure
= 28 mm Hg
Net outward pressure
Net inward pressure
= 13.3 mm Hg
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
= 6.7 mm Hg
Water and other substances leave capillaries because of a net outward
filtration pressure
Slide number: 5
Inward force
of osmotic
pressure
28 mm Hg
Blood
flow from
arteriole
Tissue
cells
Lymphatic
capillary
Inward force of
osmotic pressure
28 mm Hg
Net outward pressure
Outward force, including
13.3 mm Hg
hydrostatic pressure
Outward force,
21.3 mm Hg
including hydrostatic
Capillary
pressure 41.3 mm Hg
Net inward
pressure
6.7 mm Hg
Blood
flow to
venule
Net force at arteriolar end
Net force at venular end
Outward force, including
hydrostatic pressure
= 41.3 mm Hg
Outward force, including
hydrostatic pressure
= 21.3 mm Hg
Inward force of osmotic
pressure
= 28 mm Hg
Inward force of osmotic
pressure
= 28 mm Hg
Net outward pressure
Net inward pressure
= 13.3 mm Hg
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
= 6.7 mm Hg
Veins
 Venules
 Veins
– Thinner than arteries
– Less smooth muscle
– Valves
– Act as blood reservoirs
QOD
How is blood pressure regulated?
13.5: Blood Pressure

Arterial blood
pressure:
– Systolic pressure
– Diastolic pressure
– Pulse
Factors Influencing Blood Pressure
 Heart
action
– Stroke volume
– Cardiac output = heart rate x stroke
volume
 Blood
volume
 Peripheral resistance
– Vasoconstriction/Vasidilation
 Blood
viscosity
– Resistance
Control of Blood Pressure
 Regulation
of cardiac output
– Baroreceptors
– Medulla oblongata (cardiac center)
– Kidneys
– Exercise, body temp, fear/anger
 Regulation
of peripheral resistance
– Vasomotor center
Venous Blood Flow
 Lower
blood pressure
 Skeletal muscle contractions
 Vasoconstriction