Transcript Слайд 1 - ЗАО ОКБ "РИТМ"

On physiological mechanism of
SCENAR-therapy
A.Yu. Molchanov,
A.Ya. Cherchago
RITM OKB ZAO, Taganrog,
Russia
Investigations of SCENAR-therapy
effectiveness
Chronic coronary heart disease
Duodenal ulcer
Acute myocardial infarction
Early post-infarction angina
Neurocirculatory asthenia
Nonorganic sleep disorders
Acute renal failure in compression injury
(renal failure that accompanies crushing, crush
syndrome)
Tubo-peritoneal infertility etc.
Proven Facts
Irrespective of disease
SCENAR-therapy normalizes
- function of the autonomic nervous system
(ANS) disturbed by the disease;
- redox balance of the body, i.e. prooxidantantioxidant ratio
Hypothesis
Methods of experimental validation of
the hypothesis
Investigation of the ANS function using the
RISTA-EPD complex
Finger photoplethysmography (PPG)
Investigating the ANS function using
the RISTA-EPD complex
Assessing the level of functional activity and
tone of the ANS, balance of the segmental
apparatus function
Localizing optimal treatment zones
Finger Photoplethysmography (PPG)
Investigation of changes of systemic and tissue
regulators of oxygen transport:
- Relative changes of stroke volume (inotropic
function of the heart) and vascular resistance
- Absolute values of the heart rate variability
indices – rhythmothropic function of the heart
RR-интервал
A1
A2
Heart rate variability indices being
investigated
HR – shows the average performance level for the circulatory system
TP – shows the cooperative effect of the autonomic regulation of the
circulation and allows to estimate the activation degree of all links
of the regulatory mechanism. Sharp decrease in TR is provided by a
significant tension of regulatory systems
HF – characterizes the activity of the ANS parasympathetic part
LF – describes mainly the status of the sympathetic center of the
vascular tone regulation
VLF - is a sensitive indicator of change in the level of brain metabolism.
Growth of the VLF-component indicates the increasing involvement
of higher autonomic centers in adaptation to the action of the
investigated factor.
LF/HF allows to estimate the degree of the tone shift.
SI - Stress Index – characterizes the degree of regulation mechanism
stress. The higher the index is, the more intensely the regulation
mechanisms are working.
VLF-component
The index shows the functional state of the brain.
An increase in the power of the VLF-component of the
spectrum in response to stress (load) indicates
hyperadaptive behaviour and increased brain metabolism,
and a decrease in it indicates the afterload deficiency of
energy supply or decreased metabolism level.
Growing VLF-component of the HRV spectrum indicates the
development of a regular stage of adaptation and the
increasing involvement of higher autonomic centers in
adaptation to the action of the investigated factor.
Investigation Design
1.Investigation of the ANS initial state with the
patient in lying position using the RISTA-EPD
system, recording the finger photoplethysmography
during 10-15 mins.
2. Continued PPG recording simultaneously with the
intervention.
3. Continued PPG recording for 10-15 mins after the
intervention is completed, investigation and
classification of the ANS initial state with the patient
in lying position using RISTA-EPD.
Factors under Investigation
1. Being at rest, i.e. no action applied.
2. Standard SCENAR electrode.
3. Electric heating pad at a comfortable temperature level.
4. Kuznetsov multipin applicator.
5. Multiple (12-segment) electrode with SCENAR- DE device.
6. Add-on ‘rotating’ zone electrode with SCENAR-DE device.
7. Add-on ophthalmologic electrode.
Research results:
first stationary interval of PPG
after SCENAR stimulation
Index
Stimulation of No action
optimal zones
Stimulation of the
lumbosacral zone
n=24
n=24
n=72
HR, min-1
-1.4  3.4*
0.4  1.9**
-2.6  2
SI
1.2  65**
-23  83*
-17  82*
VLF, ms2
536  1069*
420  677
93  658**
Research results:
second stationary interval of PPG
after SCENAR stimulation
Index
Stimulation of No action
recommende
d zones
Stimulation of
the lumbosacral
zone
Exercise
load
n=24
n=24
n=72
n=18
-1.4  3.5*
-0.3  2.4**
-1.7  3.5
HR, min-1 -2.5  3
SI
-17  33**
-52  83
-46  94*
-70  43
VLF, ms2
364  1213*
184  375**
402  537
478  530
Typical body response to the action
At rest (no action
applied):
Stimulation of
recommended
zones by the
standard device’s
electrode:
Stimulation of periorbital zones by
the ophthalmologic electrode
The response can be either neutral or
positive!
Normal response at TP=500 – 1500, SI=90 –
262, LF/HF=0.9 – 2.5.
After stimulation, FA decreases by 5-10 units, the
ANS functional activity becomes normal or
moderately decreased at eutonia or
parasympathicotonia.
At TP=200-500 the ANS functional state does
not improve. After SCENAR stimulation, FA does
not change.
Stimulating the lumbosacral area
with different types of electrodes
- Standard device’s electrode – 130 sec;
- Add-on ‘rotating’ zone electrode with the
SCENAR-DE device – 160 sec;
- Multiple (12-segment) electrode with
SCENAR-DE
device - 330 sec;
- Kuznetsov multipin applicator – no
longer than 30 sec;
- Electric heating pad – no response.
Findings
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Irrespective of treatment zone location, a single 10-15 minute
SCENAR-session extends the limits of the brain metabolism
physiological change.
Maximum extension of the limits of the brain metabolism
physiological change after a single session is achieved
provided that the zones used for treatment are those
recommended by RISTA-EPD
Using dynamic electrodes for treating the lumbosacral zone
provides a stronger effect on brain metabolism as compared
with that from treating the zone with a standard device’s
electrode by application method.
The effect of the ophthalmologic electrode on the ANS
functional state can be either neutral or positive. To provide
the effectiveness of SCENAR-stimulation, before using the
electrode, 5-10 minute treatment of the lumbosacral area with
the ‘rotating’ zone or multiple (12-segment) electrode is
recommended.
Right diagnosis implies successful
treatment