Transcript The average CFU count from any BioCote® treated product was

BioCote® Antimicrobial Silver Ion Technology
Providing proven antimicrobial protection
What is BioCote®
• BioCote® is a silver ion antimicrobial
additive, it is incorporated into
AquaVENT® tubing at the time of
manufacture
• While the term ‘antibacterial’ refers
only to bacteria, ‘antimicrobial’ refers
to a wider range of organisms
including bacteria, moulds, fungi and
others.
The Global BioCote® Partner Network
Why do these big brands work with BioCote®?
The BioCote® Brand
• Internationally Recognised
• Endorsed Technology
• Tried & Trusted
• Antimicrobial Standard.
Take Home Messages
• BioCote® only approves products that achieve a minimum of a 95%
reduction in bugs
• All BioCote® additive performance data is independently generated.
• BioCote® uses silver which is a safe & naturally occurring
• BioCote® is a long lasting antimicrobial which will not propagate
resistant micro-organisms
• By partnering with BioCote® you are associated with a branded
antimicrobial technology used around the world.
Useful Phrases
• For the lifetime of the product BioCote® will reduce the numbers of
microbes, bacteria, mould, and fungi on the product
• The addition of BioCote® does not affect the performance or appearance
of the product in any way
• BioCote® inhibits the growth of microbes that can cause unpleasant
odours or bacterial degradation of the product
•
BioCote® reduces levels of bacteria, such as, MRSA, E.coli and
Salmonella on the surface of products by up to 99.9% over a 24 hour
period.
Antimicrobial Silver
Some History
• Chinese
– Silver Chop Sticks
• Romans
– Silver utensils
• Egyptians
– Silver Water Jug
Silver – Anti Microbial Benefits
Multimodal Action
• Expected
Lifetime Efficacy
• Non Leaching
• Safe, Natural,
Non-toxic
• Broad Spectrum
Efficacy
Multi-modal Action of Silver
• Silver Ions Cause
Conformation Changes in
Microbial Proteins
• Silver Ions Interfere with
DNA Replication
• Silver Ions Promote
Formation of Reactive
Oxygen Species.
1. Silver Ions Cause Conformation
Changes in Microbial Proteins
• Silver ions combine with
microbial proteins located in
the cell wall and cytoplasm,
which interferes with their
normal functioning.
• These proteins are vital for
the healthy functioning of
the cell. This loss of function
results in an overall
inhibition of microbial
growth.
2. Silver Ions Interfere
with DNA Replication
• Silver ions are known to
interfere with the way
microbes copy their genetic
material or DNA. Microbes,
like most living cells, have
to make copies of their
DNA during reproduction.
• Silver ions stop the
microbes replicating by
blocking the copying of
their genetic material.
3. Silver Ions Promote Formation
of Reactive Oxygen Species
• Silver ions are known to promote the
formation of harmful chemicals
called reactive oxygen species (ROS)
inside microbial cells.
• ROS are harmful to living cells
because they cause significant
damage to cell structures. Damage
caused by ROS is a major contributor
to functional decline, characteristic
of aging, that results in further
inhibition of microbial growth.
Determining Efficacy of BioCote®
Treated Surfaces – Independent Study
H1N1 Study
• The World Health Organisation
estimated an H1N1 pandemic could
cost the UK economy over £70 billion.
• BioCote®- approved silver ion
technology is effective at significantly
reducing numbers of infectious
influenza A H1N1 virus.
• A measure with the potential to limit
the spread of viral infection is worthy
of including in an infection control
Strategy.
H1N1 Study
• To understand how
effective BioCote®
approved silver ion
antimicrobial technology is
against influenza A H1N1
virus when incorporated
into various manufacturing
materials.
• BioCote® approved silver
ion technology is effective
at significantly reducing
numbers of infectious
influenza A H1N1 virus.
Collaborators
Published Studies
• Reduction of bacterial contamination in a healthcare environment by
silver antimicrobial technology
– Journal of Infection Prevention, 2009, vol. 10: 1, 6-12
• Campylobacter genotypes from poultry transportation crates indicate a
source of contamination and transmission
– Journal of Applied Microbiology, 2011, vol. 110: 1, 266-276
• Silver ion antimicrobial technology: decontamination in a nursing home
– British Journal of Community Nursing, 2009, vol. 14: 6, S25-29.
Aim of Studies
• To quantify efficacy (performance) of BioCote® treated products in situ*
* i.e. in the environments they were designed to operate in
18
Reduction of Bacterial Contamination
in a healthcare environment by silver antimicrobial technology
• Refurbishment at UK acute hospital
• One ward fitted with BioCote® treated products
• Comparable ward used as control
• Normal cleaning operated
• Processed for total bacterial counts.
J. Inf. Prevent. 2009
vol. 10: 1, 6-12.
Reduction of Bacterial Contamination
in a healthcare environment by silver antimicrobial technology
•
•
•
The average CFU count from any
BioCote® treated product was
92.6% lower than that from any
untreated product in the same
environment (unit A)
The average CFU count from any
BioCote® treated product was
95.8% lower than that from any
untreated product in unit B.
The average CFU count from any
untreated product in unit A was
43.5% lower than that from any
untreated product in unit B.
Unit A – BioCote Treated
Unit A – Control Ward
Treated
Products
Mean 33
CFU / Swab
95.8%
92.6%
43.5%
Difference
Difference
Difference
Untreated
Products
Mean 447
CFU / Swab
CFU = Colony Forming Unit
Untreated
Products
Mean 791
CFU / Swab
How do you Protect your Circuits During Non-use?
Summary
• BioCote® inhibits the formation of Biofilm associated with HAI’s
• BioCote® will reduce the numbers of viruses, bacteria, mould, and fungi
on the product
• BioCote® does not affect the performance or appearance of the product
• BioCote® inhibits the growth of microbes that can cause unpleasant
odours, bacterial degradation or deterioration of the product
• BioCote® reduces levels of bacteria, such as, MRSA, E.coli and Salmonella
on the surface of products by up to 99.9% over a 24 hour period
• Collaborative studies by BioCote® and virologists have demonstrated the
anti-viral properties of BioCote® treated surfaces.
Seeing is Believing
Seeing is Believing
Contact Us
www.armstrongmedical.net
[email protected]